Carlson Labs, Vitamin D3, 5,000 IU (125 mcg), 360 Soft Gels

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Product name: Carlson Labs, Vitamin D3, 5,000 IU (125 mcg), 360 Soft Gels
Quantity: 360 Count, 0.27 kg, 7.4 x 7.4 x 13.2 cm
Categories: Carlson Labs, Supplements, Vitamins, Vitamin D, D3 Cholecalciferol, Gluten Free, Casein Free, FDA Regulated Facility

Dietary Supplement, Bone Support, Immune Function, Heart Health, Providing the Highest Quality Nutritional Supplements Since 1965, Gluten-Free, Milk/Casein-Free, Preservative-Free, Potency and Quality Guaranteed, An FDA Regulated Facility, Scientific research indicates Vitamin D3 plays an important role in promoting teeth, bone, and muscle health; immune and cardiovascular system function; and calcium absorption.

In addition, seasonal variations, weather conditions, latitude, and clothing can influence plasma levels of 25(Oh)d 28, 65- 67; race, skin pigmentation, and age can also influence vitamin d levels. I was found to be severely deficient in vitamin d, to the point where it was deemed probably genetic. However, these complications have become less common over time because many foods and drinks have added vitamin d. As i explain in the article, testing vitamin d levels is generally not recommended, unless an older person has particular risk factors for deficiency. In all, 154 deaths from cancer occurred in the vitamin d group versus 187 in the placebo group. You should not take more than 4,000 iu a day of vitamin d3 unless your doctor tells you otherwise. Yet the endocrine society recommends a greater amount of supplementation for children at risk for vitamin d deficiency or low bone density mass: From 400 to 1,000 iu for children 1 year and younger, and 600-1,000 iu for all older children, adolescents, and adults. Calcitriol binds to the vitamin d receptor inside your cells, turning genes on or off.

Carlson Labs, Vitamin D3, 5,000 IU (125 mcg), 360 Soft Gels: D3 Cholecalciferol, Vitamin D, Vitamins, Supplements

Had severe vitamin d deficiency which caused my calcium levels to decline – this gave me back pain, restless legs, knee pain, weakness and depression. This topic reviews the major causes of vitamin d deficiency, including how it is diagnosed and treated, and safe ways to prevent vitamin d deficiency. In the kidneys and other organs, 25-(Oh)d changes into the active form of vitamin d, called calcitriol. Daily vitamin d supplementation is often inadequate in treating vitamin d deficiency due to poor compliance. I believe that sensible sun exposure provides many other health benefits as well as natural vitamin d3 production. Randomised controlled trials, meta-analyses and reviews of all aspects of vitamin d supplementation in humans were reviewed. Most studies have found a decrease in general symptoms when given to women with vitamin d deficiency, some finding notable reductions and some finding small reductions. Further research is, therefore, necessary to confirm the protective effect of vitamin d on the flu. Discouraging testing for vitamin d deficiency is way up in the united states, but recent studies find that supplements of the nutrient may do less than expected. I highly recommend you ask your doctor about this product if your trying to improve low vitamin d levels.

Studies show that vitamin d may ease symptoms in people with clinical depression. I do not get out much in the sun so it’s good to know i can take this supliment, then my body is not missing out on vitamin d3, and perhaps getting more of it than those that do get out in the sun without the harmful uv rays. Fortified foods – such as milk and cereal – along with egg yolks and raw shiitake mushrooms also contain vitamin d. My doc suggested that i check out the vitamin d council a few years ago, and their reccos are higher than the ones mentioned in your article. The benefits of vitamin d supplementation are restricted to a small group of patients, but the use of vitamin d is often extrapolated inappropriately to a much larger group of patients. Historically, vitamin d3 loss has been associated with rickets, a disease caused by low levels of vitamin d3 that commonly affects children. Infants suffering from such a mutation have an increased sensitivity to vitamin d and in case of additional intake a risk of hypercalcaemia. The net interactions of calcium supplementation and vdra treatments with adequate vitamin d nutrition upon cardiovascular outcomes have not been assessed. I like this tablet – it has a high dose of vitamin d – just what the doctor ordered. As far as i know, there is no high-quality research evidence indicating that supplementing an older person up to a vitamin d level of 50-60 (As compared to 20-40) is better for osteoporosis outcomes.

They suggest, for some people, reducing the risk of preventable disease requires a higher level of vitamin d than that recommended by the iom. Low vitamin d and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (Sarcopenia): The longitudinal aging study amsterdam. Vitamin a, vitamin d, cartilage, bones, and teeth. Started taking vitamin d3 and the difference was night and day. Foodpharmacy Blog does not assume liability for any actions undertaken after visiting these pages, and does not assume liability if one misuses supplements. Dose response for vitamin d3 supplementation varies widely among individuals. But for people with darker skin, (Meaning trying to get vitamin d from the sun during a lunch break is all but impossible). Low blood calcifediol (25-Hydroxy-vitamin d) can result from avoiding the sun.

For 25-hydroxyvitamin d assessment, most trials had archived blood samples of subjects and performed measurement of 25-hydroxyvitamin d levels at baseline and during the trial on random samples of the control and intervention groups. We first performed graphical exploration of data and then an investigation of variability of changes in 25-hydroxyvitamin d levels due to doses, type of vitamin d, calcium supplementation, 25-hydroxyvitamin d baseline values, gender, mean age, type of population, length of follow-up, country, and publication year through meta-analytic methods. This is mostly due to vigilant sun protection, since sunscreen with spf 30 reduces vitamin d production by 95%. This level is often considered as reflecting long-term individual vitamin d status. Because the vitamin d content in human breast milk is low, breastfed infants typically develop low vitamin d levels unless they receive supplementation or plenty of exposure to sunlight. Mushrooms exposed to ultraviolet light contribute useful amounts of vitamin d. Vitamin d is fat-soluble and dietary sources from food or supplements are absorbed via the lymphatic system in the proximal small bowel. Paralympic athletes and athletes with illness that could influence serum 25(Oh)d concentrations or alter their responses to vitamin d3 supplementation were excluded.

Carlson Labs D3 Cholecalciferol

Our systematic review shows that changes in serum 25-hydroxyvitamin d level obtained with vitamin d supplementation in caucasian subjects age 50 and older depend on the dose taken and on the type of vitamin (D2 or d3). Blood tests taken before i started using it showed my vitamin d level was 8, it should be 80 or over. Inverse associations were found between increases in 25-hydroxyvitamin d levels and the baseline serum 25-hydroxyvitamin d levels or the concomitant intake of calcium supplements, but these associations were not statistically significant. Your body produces vitamin d when the skin is exposed to sun, and it is estimated that most people need 1,000 to 1,500 hours of sun exposure throughout the spring, summer, and fall to obtain the necessary amount of vitamin d. The active vitamin d metabolite calcitriol mediates it’s biological effects by binding to the vitamin d receptor (Vdr), which is principally located in the nuclei of target cells. Because of digestive tolerance problems, concomitant calcium supplementation may affect compliance to vitamin d supplementation and thus needs to be accounted for in statistical models. Vitamin d supplements were sometimes administered as weekly or monthly doses, principally in trials that used vitamin d2 in subjects over 79 yr old. I take vitamin d3, vitamin k2, vitamin b12, coq10, turmeric cucumin with black pepper, biotin, multivitamin, ashwagandha, glucosamine sulphate, maca root. Some rare mushrooms also harbor vitamin d, and egg yolks contain small amounts.

A number of trials also had oral calcium supplements as part of the intervention, and we abstracted this information. The top of the vitamin d treatment algorithm is to decide whether administration is for the treatment of vitamin d deficiency or insufficiency, or simply to maintain adequate vitamin d levels. Please note that cholecalciferol is available in 50,000 iu as well and is stocked in most pharmacies. Disorders that interfere with the above processes or that disrupt the small bowel mucosa can cause malabsorption syndrome and interfere with vitamin d absorption. I liked the look of the bottle and the idea of vitamin k being combined with vitamin d3, my usual vitamin d3 was always an oil-based substance contained in gelatin sometimes veggie form so i must admit i was surprised by this powder substitute. Trials that used similar supplement doses could obtain substantially different changes in 25-hydroxyvitamin d concentrations. Vitamin d supplements designed to help build bones typically contain 600 to 800 iu of vitamin d. Although, serum 25(Oh)d concentrations after supplementation reached sufficiency was observed, muscle strength did not significantly improve at this point of current meta-analysis.

Before launching into a description of the medical research, it is important to get a handle on vitamin d terminology. Everyone knows that calcium and vitamin d are important for maintaining bone health, but people often ask: How much of each do i need to take? Vitamin d can also be obtained through other sources, including fatty fish (Such as tuna, mackerel, and salmon), foods fortified with vitamin d (Such as dairy products, soy milk, and cereals), beef liver, cheese, and egg yolks. Bethesda, md: Office of dietary supplements, us national institutes of health. From vitamin d to hormone d: Fundamentals of the vitamin d endocrine system essential for good health. Thus, vitamin d 3 should be the formulation of choice for high doses of vitamin d. Human beings require and source vitamin d from diet, dietary supplements and exposure to sunlight. Older people who are confined indoors may have vitamin d deficiency even at this intake level. These two vitamin d metabolites (Called 25-hydroxyvitamin d or 25(Oh)d) are measured in serum to determine a person’s vitamin d status. To some degree, organizations like usp (Have tried to provide a non-government verification/certification in lieu of the fda providing approval for these types of supplements. Instead, the d vitamin is actually obtained by sunlight on the skin.

The biology and pathology of vitamin d control in bone. In a clinical setting, vitamin d (In combination with calcium) is most often used to treat and reverse conditions resulting in thin, brittle, and fragile bones: Rickets in children, ostemalacia in adults, and osteoporosis in older adults. Low serum vitamin d levels and tuberculosis: A systematic review and meta-analysis. Then scientists began to discover that a broad array of tissues contain proteins that serve as welcome mats for the vitamin. Much debate and uncertainty surround how much (If at all) healthy infants, children, and adolescents should be supplemented with vitamin d. 1 For example, 50,000 iu vitamin d2 every 2-4 weeks, or 800-1,000 iu d3 daily (Except if pregnant or lactating, then use 1,000-2,000 iu d3 daily) are adequate maintenance doses, whereas 50,000 iu vitamin d2 every week for 8 weeks, then every 2-4 weeks, is one approach that can be used to correct deficiency. Essential nutrient interactions: Does low or suboptimal magnesium status interact with vitamin d and/or calcium status? The effects of season-long vitamin d supplementation on collegiate swimmers and divers.