Product name: Carlson Labs, Vitamin K2, MK-4 (Menatetrenone), 5 mg, 180 Capsules
Quantity: 180 Count, 0.07 kg, 5.8 x 5.8 x 10.9 cm
Categories: Carlson Labs, Supplements, Vitamins, Vitamin K, Gluten Free, No Artificial Preservatives, FDA Regulated Facility
Dietary Supplement, Bone Support, Cardiovascular Function, Optimal Wellness, Gluten Free, No Artificial Preservatives, Potency and Quality Guaranteed, An FDA Regulated Facility, Research suggests that vitamin K2 as MK-4 (menatetrenone) promotes healthy bones and cardiovascular system function. A single capsule provides 5 mg of MK-4.
The discovery of vitamin k, it’s biological functions and therapeutical application (Pdf). When it comes to supplemental research, most studies use daily doses in the vicinity of 100 to 200 mcg per day. The importance of menaquinones in human nutrition. D, director of the vitamin k laboratory at the jean mayer usda human nutrition research center on aging at tufts university in boston. 11, 12 Low vitamin k consumption or impaired vitamin k status is associated with a higher risk of hip fracture among older women 13, 14 and men, 14 lower bone mass in older women 15, 16 and men, 16 and increased bone turnover in girls. Genetic, molecular, cellular, and human evidence support that optimal concentrations of both vitamin d and vitamin k are beneficial for bone and cardiovascular health. The rate of bmd loss at the femoral neck, but not at the lumbar spine, was significantly lower in subjects with supplemental phylloquinone compared to the other two groups. Although most of the attention in this area focuses on food sources of vitamin k1, it may also be important to monitor vitamin k2 intake.
Carlson Labs, Vitamin K2, MK-4 (Menatetrenone), 5 mg, 180 Capsules: Vitamin K, Vitamins, Supplements
Further, excessive intake of calcium supplements might also result in milk-alkali syndrome and hypercalcemia. However, taking any type of supplement can lead to toxicity. However, because green leafy vegetables are the primary dietary source of phylloquinone and because they are usually part of a balanced diet, high phylloquinone consumption may be just an indicator of healthy eating habits which may, rather than phylloquinone itself, account for all or part of the association reported in observational studies. Could any of these supplements be causing my insomnia? Studies on the absorption and metabolism of phylloquinone (Vitamin k1) in man. In one study, healthy individuals over the age of 70 years with the highest blood levels of vitamin k1 had the highest verbal episodic memory performance. He does not eat a well rounded diet to get theses vitamins through food as would be the first choice.
Menaquinone-4 in breast milk is derived from dietary phylloquinone. Gla-containing proteins (Mgp and osteocalcin) regulate many anticalcification and bone-forming processes in the body, which are dependent on vitamin k in order to be produced. A large group of people uses both vitamin d and calcium for the prevention of falls and fractures. However, higher vitamin k intakes were not associated with lower cvd mortality in a prospective study that followed 7,216 older adults at risk for developing cvd. In addition to maintaining bone health, vitamin k promotes blood vessel health by keeping arteries clear of calcification. Consuming vegetables at the same time as some fat improves phylloquinone absorption from the vegetables, but the amount absorbed is still lower than that from oils. Q: What is the difference between vitamin k and vitamin k2? The purpose of this narrative review is to summarize available evidence in the field of the synergistic interplay between vitamins d and k on bone and cardiovascular health. Unfortunately, for vegans and vegetarians, most vitamin d3 supplements do contain some type of ingredient derived from an animal product (Usually fish oil). This supplement is gluten free, vegetarian, and kosher. Most people are not deficient in vitamin k and symptomatic deficiency is rare, so unless you have a malabsorption condition or are severely malnourished, you likely get sufficient vitamin k from your diet (E. They work by decreasing or delaying vitamin k’s clotting ability.
The linus pauling institute micronutrient information center provides scientific information on the health aspects of dietary factors and supplements, food, and beverages for the general public. We also made sure to include at least one product that combined vitamin d3 with k2, as this combination has been very successful at increasing bone density in older women. To see the full set of research information and references for vitamin k. Plasma lipoproteins as carriers of phylloquinone (Vitamin k1) in humans. Many experts believe vitamin k activates proteins required for bone growth and development. Q: Who is at risk for vitamin k2 deficiency? Prolonged use of broad spectrum antibiotics, such as cephalosporins and salicylates, can interfere with vitamin k synthesis by intestinal bacteria and lower vitamin k absorption. Of note, this mk-4 dose used in most of the cited studies is about 500 times higher than the ai for vitamin k. After evaluating the dose and the quality of the solvent used to deliver it, we also considered the purity of the overall supplement design.
I keep calcium supplements to 100mg or less a day. Commercially available calcium is often marketed in combination with vitamin d3 to increase intestinal absorption of calcium (Table 1). In one trial (14 Children aged 8 to 18 years old) for one month half of the participants were given oral vitamin k supplements at a dose of 1 mg/day and the other half were given 5 mg/day. E, intake of dairy products and thus vitamin k2). Unlike many common vitamins, such as vitamin c, vitamin k2 is fat soluble, not water soluble. One 10-year population study, the rotterdam study, did show a clear and significant inverse relationship between the highest intake levels of menaquinone (Mainly mk-4 from eggs and meat, and mk-8 and mk-9 from cheese) and cardiovascular disease and all-cause mortality in older men and women. A salad dressed with olive oil, for example, will help the supplement to assimilate more readily. Although vitamin k is a fat-soluble vitamin, the body stores very small amounts that are rapidly depleted without regular dietary intake. Dietary induced subclinical vitamin k deficiency in normal human subjects. As a vitamin k inhibitor, warfarin may potentially negate these effects. At the same time, vitamin k2 ensures that calcium is deposited in your bones and teeth, where it is needed most.
Carlson Labs Vitamin K
It provides 500 micrograms of vitamin k2 in the mk-4 form as well as an additional 100 micrograms in the mk-7 form, so it might be more biologically active than single-form vitamin k supplements. (See overview of vitamin a and overview of vitamin d and overview of vitamin e and overview of dietary trace elements and overview of water-soluble vitamins and vitamin supplementation in disease prevention ). Although vitamin k is involved in the carboxylation of osteocalcin, it is unclear whether supplementation with any form of vitamin k reduces the risk of osteoporosis. Seven of these trials, which took fractures into consideration, found that vitamin k2 reduced spinal fractures by 60%, hip fractures by 77% and all non-spinal fractures by 81%. Unfortunately, we could not analyse the data from this second trial because the investigators did not report data just from the first part of the trial (Only from the end of the trial when all volunteers had been in both groups), so we could not tell if the effects were due to supplements or no supplements. Vitamin a has the scary cancer/birth defect warning because it is vitamin a! K complete provides vitamin k1, k2 as mk-4, and k2 as mk-7 in a single soft gel. There are different types of vitamin k2, and the differences are reflected in the number next to the k. As both vitamin d3 and vitamin k2 are liposoluble molecules, they will be absorbed more efficiently if they are taken with food, especially when accompanied by fatty or oily foods.
Animals that eat this feed, like chickens and cows, end up with mk-4 form of vitamin k2 in the food they produce, like eggs, butter, or meat. Phylloquinone in plasma from elderly and young adults: Factors influencing it’s concentration. Fclo was also tested for coq 10, the label claimed it contained this in the past but the covance testing showed none. Anyone who is taking any of these medications should speak to their doctor about their vitamin k intake. At this moment, we should be careful about supplementing high-dose vitamin d, unless indicated differently. 34 Thus, if further trials are performed, vitamin k 1 and k 2 should be tested. Another risk for vitamin k deficiency is the use of phosphate binders as outlined above. The key difference between vitamin d2 and d3 is their origin.
I regularly take a multivitamin, fish oil, magnesium, calcium, vitamins d and k, and a protein supplement. Vitamin d (In inactive form) is often prescribed in combination with calcium supplements. Because a synthetic form of vitamin k, vitamin k 3 (Menadione), may be toxic by interfering with the function of glutathione, it is no longer used to treat vitamin k deficiency. Talk to your doctor about your d3 levels before you start supplementing with it. However, more studies on the roles of vitamin k subtypes are needed. Both vitamins share a common 2-methyl-1,4-naphthoquinone ring, also known as menadione. Supplementation of vitamin k in pregnant women receiving anticonvulsant therapy prevents neonatal vitamin k deficiency.
But all this is somewhat irrelevant because this form of caramel color is not used by the supplement industry for making capsule shells. Adequate intake of vitamin k has also been shown to lower the risk of stroke. Without vitamin k, the body cannot produce prothrombin, a clotting factor that is necessary for blood clotting and bone metabolism. Solgar vitamin k2 is a straightforward, simple vitamin k2 supplement with 100 micrograms of vitamin k2 per capsule. Primary structure of the vitamin k-dependent part of prothrombin. You should always buy a large quantity of supplements at once, which will save you money in the long term. Vitamin k is an essential vitamin that supports blood clotting and healthy bones. The extent to which blood coagulation was restored by the diet was taken as a measure for it’s vitamin k content.
This review describes the current knowledge on menaquinones, based on the nutrient amount required to prevent deficiency and maintain optimal body stores and/or prevent chronic disease.