Product name: Country Life, Pycnogenol, 100 mg, 30 Veggie Caps
Quantity: 30 Count, 0.09 kg, 4.6 x 4.6 x 8.4 cm
Categories: Country Life, Supplements, Antioxidants, Pine Bark Extract, Pycnogenol, Gluten Free, Kosher Parve, Certified Vegan, Vegan, Vegetarian, Certified Gluten Free, Soy Free
Established 1971, Gluten-Free, Supports Cardiovascular Health, Includes Antioxidants OPCs, Dietary Supplement, Pycnogenol- Nature’s Super Antioxidant, Kosher Parve, Our Pledge of Integrity, Authenticity, Cleanliness, Freshness, Consistency, Accuracy, This product has been manufactured at a GMP Registered facility, Made from French Maritime Pine Bark, Country Life’s Pycnogenol includes antioxidants called oligomeric proanthocyanidins (OPCs). At 100 mg, it is shown to support cardiovascular health. Also available in 50 mg dose, YES Certified Vegan by the AVA NO Yeast, Wheat or Corn YES Certified Gluten-Free by GFCO. org NO Soy or Milk YES Recyclable Packaging NO Salt YES Manufacturing Supports Wind Power NO Preservatives YES Kosher Parve NO Artificial Color.
While tinnitus decreased in both groups, the decrease was more significant in those taking pycnogenol. It is an antioxidant, acts as an anti-inflammatory, selectively binds to collagen and elastin, and aids in the production of endothelial nitric oxide. The primary hypothesis was that pine bark extract would lower blood pressure in a population of overweight and obese participants with baseline prehypertension or hypertension. By becoming an examine plus member, you will have access to all of the latest nutrition research on over 300 supplements across over 500 different health goals, outcomes, conditions, and more. Of the flavonoids tested, good protection in the retina was found at 10(-5) M for epigallocatechin gallate (50%) And at 50 ng/ml for pycnogenol (61%) And catechin (52%). A trial of children with adhd found that pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing dna damage. The extract has been used for anemia, inflammation, and cardiovascular conditions. In rodent studies, pine bark extract showed antioxidant effects and improved insulin resistance and hyperglycemia. The results demonstrated a beneficial effect of pycnogenol on the progression of retinopathy.
Country Life, Pycnogenol, 100 mg, 30 Veggie Caps: Pycnogenol, Pine Bark Extract, Antioxidants, Supplements
For 12 weeks, participants took either the pine bark extract or a placebo. Pycnogenol, a standardized extract of french maritime pine bark, is composed of flavonoids, procyanidins, and phenolic acids. Research suggests that pycnogenol may protect cells in the body against oxidative stress. Evaluation of antioxidant activity was made using dpph and tbars test. Approximately 60% of patients treated with pycnogenol(R) experienced a complete disappearance of edema (The most rapidly disappearing symptom) and pain at the end of the treatment, while almost all the patients reported a reduction in leg heaviness which disappeared in approximately 33% of patients. Though it is possible that m1 is not the main mediator of maritime pine bark extract’s bioefficacy it is also conceivable that plasma is not the only compartment where m1 is present in vivo. The effects of pycnogenol on immune and haemopoietic dysfunction in senescence-accelerated mice (Sam), as a murine model of accelerated ageing, were determined. The participants were randomly assigned to take either a japanese-produced pine-bark extract or a placebo. Although the study design was weak, other studies demonstrating that pycnogenol has a relaxing effect on intestinal smooth muscle tissue lends some increased confidence that it may also be effective as a treatment for ibs. Comparative effects of enzogenol and vitamin c supplementation versus vitamin c alone on endothelial function and biochemical markers of oxidative stress and inflammation in chronic smokers. Pine bark has been used as a food source in emergencies.
Pycnogenol is an extract of french maritime pine bark (Pinus pinaster) that consists of a concentrate of polyphenols, mainly procyanidins. While pycnogenol is thought to be safe for children, they should only take it for a few weeks at a time. On the other hand, different pinus spp bark extracts have been tested against a wide range of disorders -cancer, diabetes mellitus, hypertension, atherosclerosis, neuroprotective effect and other oxidative stress and inflammatory-related diseases. It ranks as one of the top-selling herbal dietary supplements in the united states. Currently pycnogenol is available in a number of forms, as a dietary supplement, a powder or cream that is often used in cosmetics, a multi-vitamin, and other health products such as health drinks. Because of it’s favorable safety profile and sustained anti-inflammatory action, pycnogenol represents an option as an add-on supplement for oa patients. Pycnogenol, a pine bark extract, consists of phenolic acids such as p-hydroxybenjoic, p-cumaric, caffeic and ferulic acid, and taxifolin and catechin. Pycnogenol (Pyc), extracted from french maritime pine bark, has anti-inflammatory and antioxidant properties and can improve lipid profiles. Devaraj s, vega-lopez s, kaul n, schonlau f, rohdewald p, jialal i : Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile.
Pine bark extract is generally well tolerated, with occassional minor gastric discomfort, dizziness, nausea, and headache. In a study of 61 adhd children, pycnogenol reduced hyperactivity, improved attention, and motorics after 1 month. Pine bark extract has been clinically shown to help improve skin appearance and more. If possible, try to get pycnogenol from a local supplier, such as a health food store. In this study, we compared the response of human breast cancer cells (Mcf-7) and normal human mammary cells (Mcf-10) to apoptosis in the presence of pycnogenol. Maritime pine extract was effective at affording protection from oxidative stress postexercise. The ability of pycnogenol to inhibit nf-kappa b activation and vcam-1 and icam-1 expression suggests that this phytochemical may play an important role in halting or preventing the atherogenic process. Furthermore, past studies 8, 15 have shown decreases in cvd risk factors when pine bark extract was tested as an adjunct to conventional pharmacologic treatment. Pyc also participates in the cellular antioxidant network as indicated by it’s ability to regenerate the ascorbyl radical and to protect endogenous vitamin e and glutathione from oxidative stress. Studies have shown that taking 30 – 150 mg pycnogenol daily helps support the mobility and flexibility of joints and reduces aches and pains. Perimenopausal women who took pycnogenol for eight weeks noticed decreased cholesterol and triglyceride levels.
Induction of vcam-1 and icam-1 surface expression by tnf-alpha was dose-dependently reduced by pycnogenol. If you have trouble finding a supplier you trust, many of the active ingredients of pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. The low-dose buildup effect of pycnogenol as an antiinflammatory agent would make it useful in a multinutrient format, but it may not be the most potent antiinflammatory in isolation. Pine bark extract is rich in plant pigments called bioflavonoids. Preincubation of cells with physiological concentrations of pycnogenol significantly decreased no generation. A trial of 39 people with hay fever found that pycnogenol may reduce nose and eye symptoms. At six months, 87 percent of those who took pycnogenol were asymptomatic, compared to almost 35 percent of controls, and had significantly better blood flow in the cochlea (A part of the inner ear that plays a key role in hearing). Without any treatment (Placebo) the retinopathy progressively worsened during the trial and the visual acuity significantly decreased; on the contrary, the pycnogenol-treated patients showed no deterioration of retinal function and a significant recovery of visual acuity was also obtained.
Country Life Pycnogenol
Com and it’s editors do not advocate nutritional supplementation over proper medical advice or treatment and this sentiment will never be expressed through pages hosted under examine. The comparison of 42 two-dimensional protein patterns from megagametophytes of maritime pine from seven geographical origins enabled the analysis of the genetic variability of abundant proteins. As someone who is been working in the supplement industry for a very long time, i cannot advise enough only working with brands and ingredients that are deeply invested in science and production. To see the full set of research information and references for pycnogenol. Roy krebs is the founder and ceo of natural stacks, an open source supplement company with targeted brain health products to help improve mood, memory and focus. Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. While the percentage of opcs in the pine bark extract evaluated herein is comparable to that of other commercially available pine bark extracts, there are variations in monomer, dimer, and trimer chemical components of pine bark extracts with similar percentages of opcs. In the present study, we investigated whether pinus densiflora bark extract has potential to prevent cataract formation and elucidated the underlying mechanism.
In a nutshell, the french maritime pine bark extract comes from the bark of pinus pinaster growing on the coast of bordeaux, france. The phosphate buffered saline (Pbs, ph 7,4) consisted of 137 mm nacl, 2,7 mm kcl, 8,1 mm na 2hpo 4 and 1,5 mm kh 2po 4, in case of incubation with erythrocytes the pbs buffer was supplemented with 0,1% (M/v) glucose. Should i take pycnogenol or regular pine bark extract? Pycnogenol is a patented formulation of pine bark extract which is standardized to 65-75% procyanidin compounds by weight. Study results showed that 18 of the 24 participants who took pycnogenol had an improvement in their vision, while no such improvements were observed in those who took the placebo. These observations suggest an advantageous risk-benefit ratio for pycnogenol. Results of recent studies also suggest that pine bark extract may have additional cardiovascular benefits, including enhanced glycemic metabolism, 8, 9 reduced body weight, 12 and improved lipid profile. Sources especially rich in prodelphinidin were a number of ribes spp, salix cinerea and platanus acerifolia, from all of which the tannin was easily extracted.
Pycnogenol may increase the risk of bleeding, so it should be avoided by those with bleeding disorders, people taking blood thinning medication or supplements, or in the weeks before surgery. In southern france, the beautiful and lush forests are home to a species of french pine trees (Pinus pinaster) that contain unique health-promoting properties. Thus, topical antioxidants that replenish the antioxidant capacity of the skin have the potential to prevent oxidative damage. The effects of a bioflavonoid mixture, pycnogenol, were assessed on platelet function in humans. Quickly and easy look up evidence on over 400 supplements across over 500 different health goals, outcomes, conditions, and more. Histological sections of the intestines showed a dramatically better condition of the mucosal layers compared with the irradiated control animals administered water without pycnogenol. We determined the effects of pycnogenol on peroxide generation and on glutathione (Gsh)-dependent and gsh-independent antioxidant systems. Pine bark extract is composed of 80% to 85% proanthocyanidins, the monomers catechin and taxifolin (5%), And phenolic acids, including derivatives of benzoic and cinnamic acids (2% To 4%). Hiper is a mixture of french maritime pine bark extract (Pbe), honey, aloe vera, and papaya extract.
Hiper health supplement (Hiper) was formulated using a combination of french maritime pine bark extract (Pinus pinaster, pbe), aloe vera, honey, and papain. Is a powerful super-antioxidant shown in decades of research to boost blood circulation and act as a natural anti-inflammatory. We also know exactly what is in pycnogenol, that it is 100 percent natural and free from pesticides and herbicides. Children who took a pycnogenol supplement for one month had healthy antioxidant levels. There is absolutely no application of pesticides during the growing of the pine trees or toxic solvents during the manufacture of the french maritime pine bark extract, therefore it does not contain any pesticide or solvents. Forty patients with chronic venous insufficiency (Cvi) and varices of the legs were selected and double-blindly randomly assigned to a treatment with pycnogenol (French maritime pine bark extract), 100 mg x 3/day or a placebo for 2 months, according to a double-blind experimental design. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure.