Product name: Country Life, Vitamin D3, High Potency, 10,000 I.U, 200 Softgels
Quantity: 200 Count, 0.2 kg, 11.4 x 6.4 x 6.4 cm
Categories: Country Life, Supplements, Vitamins, Vitamin D, D3 Cholecalciferol, Certified Gluten Free, Gluten Free, Halal
Established-1971-, 10,000 I. U. (250 mcg), Non-Fish Liver Source, Certified Gluten-Free, Promotes Bone, Dental and Immune Health, Supports Colon Health, From Sustainable Source, Dietary Supplement, IFANCA Certified Halal, Our Pledge of Integrity, Authenticity, Cleanliness, Freshness, Consistency, Accuracy, Vitamin D aids in the absorption of calcium, helping to form and maintain healthy bones and teeth. It also supports colon and immune health. Country Life high potency Vitamin D? 10,000 I. U. comes from lanolin, a sustainable and safe source in a base of medium chain triglycerides (MCT). Also available in 1000, 2500 and 5000 I. U. strengths.
Vitamin d with or without calcium supplementation for prevention of cancer and fractures: An updated meta-analysis for the u. Patient level pooled analysis of 68 500 patients from seven major vitamin d fracture trials in us and europe. Furthermore, vitamin d intoxication has been reported after misunderstanding of physician instructions, emphasizing the need for improved communication regarding dosing. Some correlational and intervention studies note that higher serum vitamin d is associated with mildly lower blood pressure, although the evidence is somewhat conflicted and effects that have been found are rather small. For these reasons, we chose vitamin d3 for our health and wellness products. The body kinetics of vitamin d 2 and d 3 and 25ohd have significant implications on symptomatology and management during intoxication. Very high-dose ergocalciferol is effective for correcting vitamin d deficiency in children and young adults with cystic fibrosis. The drugs and therapeutics committee of the pediatric endocrine society suggests obtaining serum 25-hydroxyvitamin d levels in infants and children who receive long-term vitamin d supplementation at or above the upper level intake that is currently recommended. The best multivariate model, displayed in table 3, includes the baseline serum 25-hydroxyvitamin d level (Mean between trial arms) and the type of vitamin d supplementation. Vitamin d3 may be more than three times as effective in raising concentrations of vitamin d in the bloodstream and maintaining those levels for a longer time.
Country Life, Vitamin D3, High Potency, 10,000 I.U, 200 Softgels: D3 Cholecalciferol, Vitamin D, Vitamins, Supplements
Genetic contribution to bone metabolism, calcium excretion, and vitamin d and parathyroid hormone regulation. Vitamin d is a lipid-soluble vitamin with a steroidal structure that exerts numerous essential cellular and molecular functions. In jama cardiology, the researchers reported that supplementation made no difference. Fish oil supplements offered some benefits, preventing heart attacks, but not stroke. Fortified foods – such as milk and cereal – along with egg yolks and raw shiitake mushrooms also contain vitamin d. There are also many other benefits to vitamin d3 such as preventing colon and bladder cancer aswell as reducing your blood pressure. I know that some health providers recommend substantially higher vitamin d levels, but as best i can tell, there is no high-quality research evidence to support this. Association between inflammatory bowel disease and vitamin d deficiency: A systematic review and meta-analysis. As a vegetarian person who looks deeply cares about my health, animals and environment, it was very important to find as pure and clean vitamin d as possible. Because the body produces it, vitamin d3 is not a true vitamin, but it is usually considered a vitamin due to it’s importance in the human body. For 25-hydroxyvitamin d assessment, most trials had archived blood samples of subjects and performed measurement of 25-hydroxyvitamin d levels at baseline and during the trial on random samples of the control and intervention groups. In general, i recommend people take a daily vitamin d supplement no matter how much time they spend outside.
33, 34 The purpose of this review article is to present the biological significance of magnesium in vitamin d metabolism and it’s therapeutic importance to minimize complications related to vitamin d deficiency. In the kidneys and other organs, 25-(Oh)d changes into the active form of vitamin d, called calcitriol. An ideal way to obtain vitamin d, as few foods contain vitamin d in sufficient quantity to meet daily value levels. Frequently asked questions about vitamin d which type of vitamin d should i take? In these studies, daily intake of 50 000 iu vitamin d 2 for 28 days was required to raise 25ohd concentrations above 30 ng/ml. Vitamin d belongs to the super family of nuclear steroid transcription regulators that include thyroid hormones, vitamin a, androgens, and the glucocorticoids. The d vitamin is the only vitamin that is not obtained from foods that are consumed. Adequate intake of vitamin d has shown to diminish the risk of some of the skeletal as well as nonskeletal disorders. This brief shopping guide gives you all the info you need on selecting a safe and effective supplement and includes our top pick from nature made.
Thus, vitamin d 3 should be the formulation of choice for high doses of vitamin d. Yet, only a handful of foods contain significant amounts of this crucial vitamin, and deficiency is very common (1, 2, 3). A study in the journal of pediatrics this year found that adult-sized teens need at least 5,000 iu of vitamin d3 a day for 8 weeks to correct deficiency. Apart from the flesh of fatty fish (Such as salmon, tuna and mackerel) and fish liver oils, very little foods contain vitamin d. Foodpharmacy Blog does not assume liability for any actions undertaken after visiting these pages, and does not assume liability if one misuses supplements. The main symptoms of vitamin d overdose which are those of hypercalcemia including anorexia, nausea, and vomiting. As such, over-the-counter and prescribed vitamin d intake has followed suit. This inconsistency was likely due primarily to the dose of vitamin d administered. A fourth source of variability was probably the different laboratory tests used for measuring serum 25-hydroxyvitamin d concentrations. Empirical therapy of vitamin d deficiency with high vitamin d doses, such as stoss therapy, is discouraged without previous documentation of 25ohd concentrations and monitoring of 25ohd and serum calcium levels.
This article explains everything you need to know about vitamin d. Additionally, every supplement utilized vitamin d3 (Cholecalciferol) instead of vitamin d2 (Ergocalciferol). Although both vitamin d 2 and d 3 undergo the same hydroxylation steps and are equipotent in treating rickets, vitamin d 2 has been found less toxic in animal studies and less efficacious in raising serum 25ohd concentration than vitamin d 3, when administered in the form of boluses. In the eye, initial studies in mouse, rabbit, and human corneal epithelial cells showed expression of vdr and cyp27b1 by rt-pcr, and vitamin d metabolites were detected in the aqueous and vitreous humors by mass spectroscopy. I believe that sensible sun exposure provides many other health benefits as well as natural vitamin d3 production. This essential vitamin is responsible for building strong bones and teeth, keeping our immune system strong, and may even help stave off depression. The best marker of vitamin d status is 25-(Oh)d, she says. Unlike with the other essential vitamins, vitamin d is not found in many foods. 1,24,25-Trihydroxyvitamin d3, a metabolite of vitamin d3 effective on intestine. One study showed that 96% of people who had experienced heart attacks were low in vitamin d. Various institutions have proposed different recommendations for the amount of daily intake of vitamin d. Randomised controlled trials, meta-analyses and reviews of all aspects of vitamin d supplementation in humans were reviewed.
Country Life D3 Cholecalciferol
Chemically, the various forms of vitamin d are secosteroids, i. For more than a century, scientists have recognized that vitamin d3 is involved in bone health. There are suggestions that it also plays an important role in other aspects of human health, especially immunity and infection control; recent research on tuberculosis bacteria has she’d light on the critical role vitamin d plays in the function of t-cells, which are white blood cells that fight infection in the body. 1 For example, 50,000 iu vitamin d2 every 2-4 weeks, or 800-1,000 iu d3 daily (Except if pregnant or lactating, then use 1,000-2,000 iu d3 daily) are adequate maintenance doses, whereas 50,000 iu vitamin d2 every week for 8 weeks, then every 2-4 weeks, is one approach that can be used to correct deficiency. Yet the precise definition of vitamin d deficiency and the healthy threshold for vitamin d levels lack universally agreed-upon standards. A review of vitamin d supplementation as disease-modifying therapy. Summary estimates from this model confirmed a significant association between the supplement dose and the change in 25-hydroxyvitamin d level. 14 The effects of vitamin d supplementation on circulating levels of magnesium were investigated in patients with type 2 diabetes mellitus. Stability of vitamin d in foodstuffs during cooking. A vitamin d deficiency can also present as osteoporosis, for which over 53 million people in the united states either seek treatment or face an increased risk.
Review: The impacts of circulating 25-hydroxyvitamin d levels on cancer patient outcomes: A systematic review and meta-analysis. The two commonly available forms of vitamin d supplements are ergocalciferol (Vitamin d2) and cholecalciferol (Vitamin d3). (Meaning, the group receiving vitamin d supplementation did not appear to do better). That means vitamin d is best absorbed by the body when taken with fatty foods and is the reason many vitamin d supplements also contain an oil. The cure came not from sunshine itself, but from vitamin d, an essential chemical that the body makes in the presence of uv light. A collaborative analysis of individual participant data from 19 prospective studies assesses circulating vitamin d and prostate cancer risk. Inexpensive vitamin d could potentially slash 30 percent of the income from the billion dollar cancer and cardiac industries alone. A 100,000 iu dose of vitamin d 2 was found to decrease in vitro bacterial growth in a population with active tb and potentially prevent reactivation of latent tb infection. Idiopathic infantile hypercalcemia is caused by a mutation of the cyp24a1 gene, leading to a reduction in the degradation of vitamin d. Summary research suggests that vitamin d may have numerous benefits related to cancer, bone health, mental health, and autoimmune diseases. When the active form of vitamin d binds to this receptor, it turns genes on or off, leading to changes in your cells. Getting enough vitamin d can go a long way to boosting your health.
Some trials did not report baseline 25-hydroxyvitamin d levels (25, 30), And we took the in-trial level in the control group as surrogate for baseline levels in both control and intervention groups. In addition, giving vitamin d supplements to people at risk of deficiency has been found to reduce the risk of multiple sclerosis and certain cancers, and prevent falls in the elderly. Optimal serum 25-hydroxyvitamin d levels for multiple health outcomes. If you are active and healthy, you are unlikely to benefit from testing, you can just take a supplement as recommended. This results in inadequate amounts of active vitamin d.