Product name: Doctor’s Best, Sustained-Release Niacin with niaXtend, 500 mg, 120 Tablets
Quantity: 120 Count, 0.09 kg, 5.3 x 5.3 x 9.4 cm
Categories: Doctor’s Best, Supplements, Vitamins, Vitamin B, B3 Niacin, Vegan, Non Gmo, Gluten Free
Science-Based Nutrition, Dietary Supplement, Vegan, Non-GMO, Gluten Free, Helps Support Cardiovascular Health Low Flush, Doctor’s Best Sustained-Release Niacin with niaXtend provides niacin in a form that helps minimize the incidence of uncomfortable skin flushing that is commonly associated with niacin. Approximately 200 coenzymes are comprised of niacin that play pivotal roles in metabolism and energy production within the body. niaXtend has been tested to encourage a favorable blood lipid profile. Research suggests that niacin, in combination with a well-balanced diet, may help maintain healthy cholesterol levels that are already within the normal range, Helps support cardiovascular health, Helps encourage a favorable balance of blood lipids, Sustained-release formula decreases incidence of “skin flushing”.
Although pellagra can occur in patients with tuberculosis treated with isoniazid, it can be prevented with increased intakes of niacin. The use of vitamin therapy for joint mobility. It is important to talk with your physician regarding taking niacin. Present-day uses of niacin: Effects on lipid and non-lipid parameters. If you are pregnant, do not take prescription niacin for high cholesterol. Many doctors advise against self-medicating with niacin and suggest that in many cases supplementation is not needed. Previous research has not identified any stroke risk related to taking niacin. Generally, high doses of niacin are used to control specific diseases.
Doctor’s Best, Sustained-Release Niacin with niaXtend, 500 mg, 120 Tablets: B3 Niacin, Vitamin B, Vitamins, Supplements
The appropriate dosage and titration of extended-release niacin should only be done under the supervision of a health care provider. The authors of the article state that more research is needed before niacin ends it’s term as a cholesterol therapy mainstay. Taking large amounts of niacin (A form of vitamin b3), such as 2 to 3 grams per day, may impair glucose tolerance and should be used by people with diabetes only with medical supervision. Those taking medications or those that have medical conditions should contact a medical professional before taking niacin due to drug interactions and side effects. It is also known as niacin (Nicotinic acid) and has 2 other forms, niacinamide (Nicotinamide) and inositol hexanicotinate, which have different effects from niacin. Al, as long as the dosage is 500 mg a day which i think this niacin supplement contains you should be below the toxic limit. However, the alleged safety advantage of inositol hexaniacinate needs to be confirmed by additional clinical trials. In a recent randomized, placebo-controlled trial in 120 healthy adults (Ages, 60-80 years), daily supplementation with nicotinamide riboside (250 Mg or 500 mg) and pterostilbene (A sirt activator; 50 mg or 100 mg) for eight weeks showed a favorable side effect profile, with no evidence of higher incidence of adverse effects compared to placebo. According to the national institutes of health, the following are the most common side effects of niacin: Headache, nausea/vomiting, diarrhea, stomach upset, and bloating.
Some people use niacin or niacinamide for acne, leprosy, attention deficit-hyperactivity disorder (Adhd), memory loss, arthritis, preventing premenstrual headache, improving digestion, protecting against toxins and pollutants, reducing the effects of aging, lowering blood pressure, improving circulation, promoting relaxation, improving orgasm, and preventing cataracts. One of the side effects of niacin is that it can increase blood sugar in people with diabetes. Niacin, also called nicotinic acid or vitamin b3, is a water-soluble member of the complex of b vitamins. Some of these disorders might respond to niacin supplementation. Liver disease: Niacin or niacinamide might increase liver damage. For children and adolescents, niacin rdas are extrapolated from adult values on the basis of body weight. An increase in daily niacin intake of 6,2 mg was associated with about a 40% decrease in cases of cancers of the mouth and throat, while a 5,2 mg increase in daily niacin intake was associated with a similar decrease in cases of esophageal cancer (58, 59). Medications used for lowering cholesterol (Statins) niacin can adversely affect the muscles.
The most common side effect is called niacin flush, which is a burning, tingling sensation in the face and chest, and red or flushed skin. I would definitely recommend taking niacin. The recommended amount of niacin for pregnant or breast-feeding women is 30 mg per day for women under 18 years of age, and 35 mg for women over 18, allergies: Niacin might worsen allergies by causing histamine, the chemical responsible for allergic symptoms, to be released. When rats with ischemic stroke were given niacin, their brains grew new blood vessels, according to researchers at henry ford hospital in detroit, michigan. Long-term administration of chemotherapy agents has been reported to cause symptoms of pellagra; therefore, niacin supplementation may be needed (See pellagra causes). 5 Function of niacin what does niacin do in the body? High doses of niacinamide may damage the liver or kidneys and make liver disease or kidney disease worse. People taking rosuvastatin might benefit from taking niacin, though they should consult with their healthcare provider before starting the supplement. Low-dose aspirin and ibuprofen reduce the cutaneous reactions following niacin administration.
When taken with niacin, some statin drugs may become more toxic so there is a possibility of an adverse interaction. Allergies: Niacin and niacinamide can make allergies more severe because they cause histamine, the chemical responsible for allergic symptoms, to be released. And you get niacin from eating certain foods including beef, chicken, tuna, sunflower seeds, salmon, green peas, turkey, and mushrooms. Your body also naturally synthesizes niacin from the amino acid tryptophan you get from food. A: Niacin is a b vitamin that has been shown to reduce cholesterol and triglyceride levels. High doses of niacinamide can increase the risk of irregular heartbeat, which is especially concerning for people with heart disease. After taking this once a day for a month, paired with a niacinamide serum, it has done wonders for my skin. To receive a copy of these test results or any other purebulk supplement please fill out the coa request form found here.
Doctor’s Best B3 Niacin
The societies also recommend that patients not use nicotinic acid supplements or stop using them if their hepatic transaminase levels are more than two or three times the upper limits of normal; if they develop persistent hyperglycemia, acute gout, unexplained abdominal pain, gastrointestinal symptoms, new-onset atrial fibrillation, or weight loss; or if they have persistent and severe skin reactions, such as flushing or rashes. However, they can have negative side effects, so you should always discuss with your healthcare provider before taking niacin. Although the results of this review do not support taking supplements to reduce the risk of cardiovascular disease, some supplements have other benefits and are recommended if people have deficiencies. However, there is not much expert consensus on whether taking supplements of vitamins and minerals is beneficial for the prevention and treatment of cardiovascular disease. Clofibrate and niacin in coronary heart disease. More severe niacin deficiency can cause a condition called pellagra. Stop taking niacin at least 2 weeks before a scheduled surgery. This enables us to offer a supplement that does not require any unnecessary chemicals, excipients, binders or unnatural fillers. There appears to be an increase in fasting glucose concentrations among users of pharmacological doses of niacin when compared to controls, thought to be related to insulin resistance. The amounts of niacinamide and vitamin b6 used in this research may cause significant side effects and may require monitoring by a doctor.
People with a history of liver disease, kidney disease, or stomach ulcers should not take niacin supplements. Supplementation with large amounts of niacin (Also called nicotinic acid) can increase blood glucose levels in diabetics, which might interfere with the blood-sugar-lowering effects of repaglinide. However, large amounts of niacin taken with pravastatin might cause serious muscle disorders (Myopathy or rhabdomyolysis). These large amounts of niacin have the potential to cause side effects, including liver damage, and should be taken only with the supervision of a doctor. Taking niacin and tryptophan together might increase levels and side effects of niacin. Taking niacin seems to improve levels of cholesterol and blood fats called triglycerides in hiv/aids patients with abnormal blood fat levels due to antiretroviral treatment. Severe reversible hyperglycemia as a consequence of niacin therapy. In some cases, fortified foods and dietary supplements may be useful in providing one or more nutrients that otherwise may be consumed in less-than-recommended amounts. Diabetes: Niacin and niacinamide might increase blood sugar. One effective way to reduce flushing with instant-release niacin and extended-release niacin is to take a 325 mg aspirin tablet 30 minutes prior to taking your niacin. A positive side effect of niacin therapy is reduction of cholesterol levels.
I read you can take too much niacin and experience serious side effects, so i picked the lowest dose i could find, 250mg. Liver function testing is recommended when niacin is taken in excess of 500 mg daily. A systematic review on evidence of the effectiveness and safety of a wax-matrix niacin formulation. The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol rationale and study design. High amounts (Several grams per day) of niacin, a form of vitamin b3, lower cholesterol, an effect recognized in the approval of niacin as a prescription medication for high cholesterol. A number of studies have found that certain b vitamins may benefit people with osteoarthritis. Niacin comes in many different forms, including immediate-release, slow-release, controlled-release, and extended-release, and is available both by prescription (Niacor, niaspan) or over the counter (Slo-niacin and many others). Most b vitamin supplements come in capsule or tablet form. This form of vitamin b3 does not typically cause a skin flush and is said to be safer for the liver than niacin.
Niacin is also taken by mouth for preventing vitamin b3 deficiency and related conditions such as pellagra. Quickly and easy look up evidence on over 400 supplements across over 500 different health goals, outcomes, conditions, and more. Taking niacin by mouth along with medicines called bile acid sequestrants might reduce hardening of the arteries in men with this condition. First time ever w/a supplement i could feel a difference in memory within a short period of time! Studies show that the benefits to lowering bad cholesterol with the ih form of niacin are not nearly as effective as free-from niacin. Those with gout or liver diseases should avoid taking high doses of niacin. It is due to a deficit in the intestines and kidneys, making it difficult for the body to break down and absorb dietary tryptophan (An essential amino acid that is utilized to synthesize niacin).
This version of niacin is less effective at increasing hdl and lowering triglycerides than the prescription niaspan.