Doctor’s Best, Vitamin D3, 125 mcg (5000 IU), 360 Softgels

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Product name: Doctor’s Best, Vitamin D3, 125 mcg (5000 IU), 360 Softgels
Quantity: 360 Count, 0.14 kg, 11.2 x 6.1 x 6.1 cm
Categories: Doctor’s Best, Supplements, Vitamins, Vitamin D, D3 Cholecalciferol, Non Gmo, Gluten Free, Soy Free

Science-Based Nutrition, Helps Support Immune, Heart and Bone Health, Dietary Supplement, Non-GMO / Gluten Free / Soy Free, Doctor’s Best Vitamin D3 provides D3 (as cholecalciferol) needed for the body to regulate phosphorus and calcium levels for healthy bones, teeth and heart. Vitamin D3 is produced in the skin by absorbing the sun’s UV rays and is obtained from food in limited amounts. Sun protection and climate factors may influence low Vitamin D3 levels. Vitamin D3 is beneficial for immune, cardiovascular, bone density and structure, and cellular function. It palys a role in most organs and systems of the body and influences the chemical messengers of the immune system, Helps regulate calcium and phosphorus levels needed for healthy bones and teeth, Helps support immune and heart health.

The concentrations of vitamin d precursors produced in the skin reach an equilibrium, and any further vitamin d produced is degraded. Under physiological conditions, 1,25(Oh) 2d has high affinity for the vitamin d receptor (Vdr), making it the active vitamin d metabolite. In the united states, vitamin d supplementation is primarily available as vitamin d2 (Ergocalciferol) and vitamin d3 (Cholecalciferol). 35- 39 Optimal health benefits of exogenous and endogenous vitamin d might not be achieved without the adequate presence of magnesium, as the bioactivity of vitamin d is a magnesium-dependent process. There have been recent concerns about the propensity of calcium and vitamin d supplementation to cause cancer. Furthermore, vitamin d intoxication also exerts significant undesirable actions on the cardiovascular system via elevations in serum phosphate and serum calcium/calciproteins, impairment of vsmc elastin biology, and inhibition of protective vascular pth/pthrp receptor signaling. Institute of medicine ; 4) A meta-analysis on vitamin d supplementation for fall prevention ; And 5) a review of vitamin d and calcium supplements on health outcomes commissioned by the u. Another study of people living in hawaii found that many had lower vitamin d levels than one might expect.

Doctor’s Best, Vitamin D3, 125 mcg (5000 IU), 360 Softgels: D3 Cholecalciferol, Vitamin D, Vitamins, Supplements

Very high-dose ergocalciferol is effective for correcting vitamin d deficiency in children and young adults with cystic fibrosis. Severe vitamin d deficiency can lead to rickets, when bones have insufficient calcium and phosphorus levels, resulting in bone softening and weakening before growth plates close. Because the vitamin d content in human breast milk is low, breastfed infants typically develop low vitamin d levels unless they receive supplementation or plenty of exposure to sunlight. The drug information above is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. Vitamin d deficiency remains the main cause of rickets among young infants in most countries, because breast milk is low in vitamin d and social customs and climatic conditions can prevent adequate sun exposure. Been taking these because of a vitamin d deficiency my latest blood test however shows my levels are even lower after taking for 2 months! Comparison of oral alendronate versus prednisolone in treatment of infants with vitamin d intoxication. Seasonal changes in human plasma levels of 25-hydroxyvitamin d. Nutrition advice: The vitamin d-lemma. Today, enthusiasm for the vitamin, at least in scientific circles, is fading, says clifford rosen, an osteoporosis researcher at the maine medical center research institute in scarborough.

Nutritional rickets: Deficiency of vitamin d, calcium, or both? Older adults often do not consume enough vitamin d-rich foods, and even when they do, absorption may be limited. Photosynthesis of vitamin d in the skin: Effect of environmental and life-style variables. It is therefore essential to ensure that the recommended amount of magnesium is consumed to obtain the optimal benefits of vitamin d. Although people can take vitamin d supplements, it is best to obtain any vitamins or minerals through natural sources wherever possible. You need to take magnesium in order for vitamin d to work well. Congenital rickets due to vitamin d deficiency in the mothers. There is a lot of debate about what the ideal vitamin d level should be, and how high is too high. Metabolic and immunological consequences of vitamin d deficiency in obese children. This inconsistency was likely due primarily to the dose of vitamin d administered. The many faces of vitamin d deficiency rickets. Vitamin d agonists (Vdras) are vasculotropic hormones, and vitamin d insufficiency is associated with significant, undesirable changes in cardiovascular physiology and structure. Research on vitamin d supplements, including large-scale clinical trials, is continuing.

Effects of vitamin d supplementation on 25-hydroxyvitamin d, high-density lipoprotein cholesterol, and other cardiovascular disease risk markers in subjects with elevated waist circumference. Future considerations not addressed specifically by studies in this review include: Vitamin d doses to prevent the winter decline of serum 25(Oh)d; Vitamin d supplementation in healthy, nonelderly adult populations; and The duration of the serum 25(Oh)d increase following supplementation. 14, 70, 71 Magnesium is the second most abundant intracellular cation and plays a key role in bone mineralization by influencing the synthesis of the active vitamin d metabolites. The vitamin d 2 content in mushrooms and cladina arbuscula, a lichen, increase with exposure to ultraviolet light. Cholecalciferol supplementation alters gut function and improves digestibility in an underground inhabitant, the naked mole rat (Heterocephalus glaber), when fed on a carrot diet. Previously i had been alternating the vitamin d pill with the gingko i. You should avoid or limit alcohol consumption while taking vitamin d3 because alcohol can decrease it’s absorption. There have been dozens of clinical trials testing the effects of supplementation of vitamin d, often with calcium, on various medical conditions. In addition, seasonal variations, weather conditions, latitude, and clothing can influence plasma levels of 25(Oh)d 28, 65- 67; race, skin pigmentation, and age can also influence vitamin d levels.

Much less data supports a cause-and-effect relationship between vitamin d supplementation and prevention of specific diseases. Vitamin d3 (Cholecalciferol) is the same form of vitamin d that the body manufactures when skin is exposed to ultraviolet (Uv) radiation from the sun. British doctor edward mellanby noticed dogs that were fed cod liver oil did not develop rickets and concluded vitamin a, or a closely associated factor, could prevent the disease. 33, 34 The purpose of this review article is to present the biological significance of magnesium in vitamin d metabolism and it’s therapeutic importance to minimize complications related to vitamin d deficiency. Click here for a chart that shows average lead levels in supplements we tested. The specific vitamin d intake that results in excess or intoxication and the severity of corresponding hypercalcemia have not been clearly established in pediatrics. Our take: A high-potency d3 supplement in softgel form. The biology and pathology of vitamin d control in bone. Numerous studies have hypothesized an interaction between vitamin d and the gh/igf-1 axis not just for patients affected by rickets. Too much vitamin d can be harmful, including (Ironically) increasing fractures, falls, and kidney stones, and can be toxic by causing excessive levels of calcium.

Doctor’s Best D3 Cholecalciferol

If not treated with vitamin d and calcium supplementation, rickets becomes osteomalacia after the growth plates close. The uncertain significance of low vitamin d levels in african descent populations: A review of the bone and cardiometabolic literature. In head-to-head studies, vitamin d 3 was almost twice as potent as equimolar vitamin d 2 And elicited a greater, more sustained, and more rapid serum 25(Oh)d response than vitamin d 2 (31, 41, 52). Manufactured foods fortified with vitamin d include some fruit juices and fruit juice drinks, meal replacement energy bars, soy protein-based beverages, certain cheese and cheese products, flour products, infant formulas, many breakfast cereals, and milk. With regard to the musculoskeletal system, future study may explore the synergistic effect of vitamin d and magnesium levels along with osteopathic manipulative treatment on performance. That said, i agree with those who say that vitamin d testing is often overused. The effects of vitamin d deficiency in athletes. Some researchers argue that the much-mentioned safety level of 2,000 iu daily does not apply to vitamin d2, due to it’s decreased potency. – Vitamin d3 is more potent than vitamin d2 in it’s ability to raise serum 25(Oh)d. A metabolite of vitamin d active in intestine. Is the preferred form of vitamin d, identical to the type manufactured by the body when skin is exposed to uv sunlight.

Yet the endocrine society recommends a greater amount of supplementation for children at risk for vitamin d deficiency or low bone density mass: From 400 to 1,000 iu for children 1 year and younger, and 600-1,000 iu for all older children, adolescents, and adults. In general, vitamin d 2 is found in fungi and vitamin d 3 is found in animals. The best way to tell if you need to supplement with vitamin d is to get a blood test from your doctor. Now enter vitamin k2, research shows that supplementing with k2 helps determine where calcium goes in your body, sending it to your bones and teeth where you need it most. Quickly and easy look up evidence on over 400 supplements across over 500 different health goals, outcomes, conditions, and more. But too much sun poses it’s own risks, and taking vitamin d supplements other than to avoid deficiency is not going to make you healthier. Assessment of vitamin d nutritional and hormonal status: What to measure and how to do it. Additionally, vitamin d has been the subject of numerous studies for it’s effect on the immune system by promoting phagocytosis and immunomodulatory functions. Should you take vitamin d during the summer months?

However, it is important to follow dosing instructions closely and to avoid taking multiple products that contain vitamin d (Eg, multivitamin and vitamin d). Lowered pth concentrations in response to vitamin d supplementation have been associated with lower fracture risk (54, 55). However, the discussion has generated confusion among treating physicians and the public about appropriate vitamin d levels and supplementation. Effect of monthly high-dose vitamin d supplementation on cardiovascular disease in the vitamin d assessment study. Inexpensive vitamin d3 supplement capsules are full of lanolin which has been subjected to intense uv-b irradiation. A united states institute of medicine (Iom) report states: Outcomes related to cancer, cardiovascular disease and hypertension, and diabetes and metabolic syndrome, falls and physical performance, immune functioning and autoimmune disorders, infections, neuropsychological functioning, and preeclampsia could not be linked reliably with calcium or vitamin d intake and were often conflicting. Given that both ergocalciferol and cholecalciferol undergo metabolic changes in the human body, which differ from other animals, it should make sense that a binding study in rats may not be sufficient to show equivalence.

We suggest vitamin d3 when possible, rather than vitamin d2, because vitamin d3 is the naturally occurring form of the vitamin and it may raise vitamin d levels more effectively. Foodpharmacy Blog cites a slew of studies supporting the notion of risk from high doses (And the consequent high blood levels) of vitamin d. Photobiology of vitamin d in mushrooms and it’s bioavailability in humans.

Doctor’s Best, Vitamin D3, 125 mcg (5000 IU), 360 Softgels Product Review

Great vitamin about a nice price.3 naive questions about vitamin D. D 10. 000. Worker D3. Not for permanent admission.5000 IU drink with a deficiency of vitamin D, established by blood tests, short courses, on the recommendation of a doctor. High dosage. I recommend. Good vitamin. recommend. Drinking The Whole Family All Year

I am an office worker, I live in the middle lane. An analysis conducted in the summer revealed an acute shortage of vitamin D. The endocrinologist prescribed a daily dose of Vit D at a dose of 5000 IU. Seeing on a jar that this dose is 625% of the daily norm, I was finally amazed. But I really trust my endocrinologist, so I began to take it calmly. Daily, simultaneously with omega (750 mg) in the morning after eating. Improved mood and sleep. Repeated analysis showed replenishment to the lower limit of the norm, I continue to take further. A very important vitamin for our body! It is great that now it can be taken in a convenient form once a day, without suffering from drops. Good quality and nice price!

1. WHOM DO I ACCEPT THIS PREPARATION? This drug, like any synthetic vitamin, is better not to take at all. Vitamin D is better to get out of food / to regularly visit the sun. But D3 is perhaps one of the few synthetic vitamins that official medicine did not say categorically “no” as a means of preventing a number of serious diseases (primarily prostate and breast cancer). In particular, the Canadian Cancer Research Association recommends that all residents of Canada take 1000 IU of Vitamin D3 every day during the winter months, since there are few sunny days in winter. And people over 65 years old and those who do not get much exposure to the sun should take vitamin D3 all year round. In the latter case, it is desirable to monitor the vitamin D content by quarterly blood tests.2. IS THERE A DIFFERENCE WHICH VITAMIN D RECEIVE? Yes, it is better to drink D3 (Cholecalciferol) – as in this drug. Vitamin D2 (Ergocalciferol), according to several studies, can be toxic.3. DOES THERE HAVE SUCH A HIGH DOSAGE OF 5000 IU? Because vitamin D3 is fat-soluble – the body can create its depot. Therefore, vitamin is not necessary to take daily. In particular, if you want to follow the preventive dosage recommended by the Canadian Cancer Research Association (see above), you can take 1 capsule from Doctor’s Best 1 every 5 days. For comparison: stay in the midday sun for 20 minutes provides a synthesis of 8,000 to 10,000 IU of vitamin D. If you want to take 1 capsule from Doctor’s Best daily, you should consult a doctor. More reviews – on my page The-best. I hope it helps you to choose the best on Ayherbe. I will be grateful if you press YES!

Since I lead a completely dissolute life with daily intake of alcohol and other temptations of this world, I do not have the opportunity to fully appreciate the properties of the drug. I really believe that it is thanks to him that I can still consciously write reviews.

I take vitamin D3 continuously for 4 years, 5 thousand units. since the beginning of this summer, I accept 10 thousand units, i. e.2 capsules, despite the fact that I travel to the sea. By the way, if you have a normal level of vitamin D3 in the body, your skin does not burn on the skin, and quickly recovers, even if you forgot to update the cream. Do not believe who writes here that you can get it by walking along the streets for 20 minutes. This is complete nonsense. As well as getting an overdose, our standards are outdated a long time ago at 400 IU daily dose will not work. The lack of this hormone, and this hormone is very important for the work of our entire body, almost the entire population of Russia lives with a lack of this vitamin, a large number of people get sick and die from cancer every year. From the lack of this vitamin (hormone) there are 18 types of cancer, it has already been proven. It can be obtained only when the sun is at its zenith and you stand 30 minutes as naked as possible WITHOUT SPF PROTECTION, in this case you will receive 2000ME. Vitamin D3 plays a large role for the immune system, without it, aging comes faster, for women in this regard it is important, with its lack of menopause comes sooner. My family constantly takes 5 thousand units. For 4 years of admission, all have increased immunity. During this time, they ceased to hurt. Even what snot is, no one remembers. Tissue regeneration and healing is mega fast. And he needs to be constantly supported, he quickly leaves, if suddenly stress, if suddenly there was an operation, if they suddenly took antibiotics. I recently passed his level after constant admission and he was 89, I want to raise to 100 and maintain the level constantly. So everyone’s health, and don’t listen to the ravings about the overdose that you can get if you take 50,000 IU. up to 10,000 are normal doses, especially in winter.

I wrote articles on vitamin D and calcium in my blog. These two elements depend on each other – vitamin D contributes to the absorption and regulation of calcium in our body. Articles will be useful to those who are just thinking about taking vitamin D and calcium, and those who already drink them. The latter will be able to compare the adequacy of their dosages with the norms proposed by the Russian Association of Endocrinologists (RAE)? It is known that vitamin D must be taken additionally as supplements, because it is low in foods, and the synthesis of vitamin D in the body under the action of UV is hampered by many factors? THIS VITAMIN D-3 from Doctor’s Best contains a dosage of 5000 IU in a single capsule. Vitamin D3 here from lanolin – wool sheep fat. This is the most common method of obtaining natural – natural vitamin D3. For better absorption of vitamin D3, extra virgin olive oil was added to the gelatin capsule? However, this dosage is above the safe upper limit and is not suitable for permanent prophylactic administration. This dosage is corrective, drink it with a deficiency of vitamin D, established by blood analysis 25 (OH) D, in short courses, as recommended by the doctor. An overdose of fat-soluble vitamins, which include vitamin D, is more difficult than a deficiency? The Russian Association of Endocrinologists recommends daily prophylactic intake of vitamin D in dosages: children up to a year – 400 IU, from 1 year to 50 years – 600 IU, 50 years and older – about 800-1000 IU, pregnant and nursing – 800 -1000. Preventive dosages do not require correction even during active sun exposure.1000 IU can be attributed to the optimal prophylactic dosage of an adult. Now Foods, for example, has vitamin D in the 1000th dosage, I like it very much, I added it to my list of favorite foods on my reviews page.

The famous vitamin D3 – tens of thousands of articles have already been written about it, how it is useful and how much it is needed. The main factors you need to know about it: we cannot get vitamin D3 from food, the only way to saturate our body with this vitamin is to be in the sun. Unfortunately, today, due to our meager lifestyle in nature, and living in the northern latitudes of our planet, people do not physically receive the right amount of vitamin D3. Not only do we have half a year, it is gloomy and not sunny in the cold season, but in the summer of good weather, too, has become scarce lately. And in addition, people simply have no time to be in the sun, even in the summer, because of today’s high pace of life. Personally, I think that vitamin D3 should be taken from around the beginning of November to the end of February. Many will say “what are you, we don’t have enough of it in the summer and we need to drink it in the summer”, you can’t take one vitamin all year round so that different paid scientists do not say there in order to increase sales of supplements. The body itself must also produce this vitamin; the body, after all, produces vitamin D3 in any case in the summer, but its greatest need is in the period that I wrote about above. What is most important to know about the benefits of vitamin D3 – regulating the balance of calcium, phosphorus and magnesium; regulates hormones; spreads elements throughout the body; promotes cells to divide properly; promotes the correct exchange of processes; supports vision. This is only an insignificant part of everything that this vitamin is needed for, the spectrum of benefits of vitamin D3 is huge. As for the dosage, the dosage should be adequate. I myself have witnessed how a person, due to a high dosage of vitamin D3, developed sand in his urine, the so-called oxalates, that is, organic salts. This is serious. A person may not know for weeks about his metabolic disorder until his urine turns red. I will share with you only my personal opinion on the correct dosage of vitamin D3, based on adequate statistics from scientists from different countries. Children under 12 years of age cannot even come close to this. For children from 12 to 18 years, the dosage should not exceed 400 IU / day. For adults, for prevention, the dosage should not exceed 1000 IU / day. For therapeutic purposes, everything is individual and everything is strictly according to the doctor’s recommendations.

Very good vitamin D3. Wellness has improved. Small capsule, comfortable to receive. The whole family accepts with pleasure!

A good budget option, in that dosage, which is recommended for filling the deficiency of vitamin D3. In the cold season, she drank two capsules. The skin first felt the use of this drug. became less dry.

good dose for prevention

I drink even in the summer, the beautician said to drink all year round, the tan is even less on the skin if he is in sufficient quantities.

Questions and Answers

Where is the D3 sourced from? After feeling like a complete idiot (from taking a D3 supplement that was made with Soybean Oil), I want to make sure this is a truly Non-GMO D3, and something that is truly GMP safe. Please do not tell me to go to the manufacture for the info, (I would appreciate an independent, honest response).
what is the price in US dollars?
Do you have D3 in veggie/fish softgel?I dont like bovine gelatin
Is it possible to use this pills in case you are pregnant or nursing?
Is the gelatin of the pig or not? please answer
i am 30 years old man should i take this?
Hello,
Is the softgel animal based or plant based?
Hi, I would like to purchase Vitamins D3 5000 iu. All the time out of stock. When it will be available? Thanks
Hi Seller, This product is halal? This subtible for Muslim? plz reply. Thanks

I have been taking this for quite a while and I rate it very highly. I too will not put anything in my body if it contains soy and this company states the product does not contain any soy.
When I bought this last 11/9/18, each bottle of Vitamin D3 2000 IU, 180 softgetls, cost US$6.20. Hope this helps.
Foodpharmacy Blog’s house brand contains the same potency in a fish softgel (/pr/California-Gold-Nutrition-Vitamin-D-3-5-000-IU-90-Fish-Gelatin-Softgels/70316). I have used the California Gold product with great success and recommend it highly. I recently had my vitamin D levels tested for the first time and it was an excellent 60! Not bad for someone who works overnights and lives in a northern climate.
It is always best to check with your doctor or equivalent during pregnancy and when breastfeeding as to what supplements to take. It doesn’t hurt to do some research first and if you are taking prenatal vitamins, check concentration of D3. Here is a link to Medscape article about this question: https://www.medscape.com/viewarticle/852915 This article supports additional D3 especially during winter months of reduced daylight hours.
Really I don’t know. l hope someone can help you.
It depends upon how much sun exposure you receive on a daily basis as well as your geographical location. A good many health practitioners are now finding signs of Vitamin D deficiency in clients who have shunned the sun out of fear of skin cancers. I have read that unless you’re exposed to sunshine in regular daily quantities, then most people are likely to be deficient in Vitamin D3, and more so for those in colder climates, or those who, for religious reasons, wear more clothing. Discussion with a health care practitioner would be advisable. I also recommend taking Lycopene if out in the sun on a regular basis.
What’s your question?
Plant
I am a Christian and don’t care about my food being Halal. That is something you would have to ask the company. I’m sorry.