Product name: Eclectic Institute, Organic Milk Thistle, 2 fl oz (60 ml)
Quantity: 2 fl oz, 0.11 kg, 3.8 x 3.8 x 11.4 cm
Categories: Eclectic Institute, Herbs, Homeopathy, Milk Thistle Silymarin, USDA Organic, Certified Organic, Non Gmo, Dairy Free, Casein Free, Vegan, Certified Organic By Oregon Tilth
Grain-Free Alcohol, Since 1982, Herbal Extract, Dietary Supplement, Silybum Marianum Seed, 1,000 mg/ml Herb Equivalency, USDA Organic, Non-GMO, Gluten/Soy/Dairy-Free, Full Strength, Made in USA, Vegan, Organic Alcohol, Certified Organic by Oregon Tilth.
Pilosa is used as an herbal medicine for a variety of diseases. Silymarin gel (1%) Containing 80% active ingredient based on silymarin flavonolignans was applied twice daily to the soles and palms for the 9-week chemotherapy cycle. Given this phytomedicine’s well established safety and it’s reasonable documentation of efficacy, future clinical use of milk thistle extract should be explored as an adjunct therapy in chemotherapy to help offset the effects of powerful and potentially hepatotoxic conventional drugs. Upon further questioning and cessation, it was determined that milk thistle was related to her symptoms. The researchers found that the silymarin gel reduced the severity of the radiodermatitis and delayed it’s occurence after 5 weeks of application. Rats and dogs have received silymarin at doses of 50 to 2,500 mg/kg of body weight for a 12-month period. A well known hepatic antioxidant, silymarin, from the milk thistle (Silybum marianum), inhibits liver damage by scavenging free radicals among other mechanisms. We feature natural care, diet and training advice, information about complementary therapies like chiropractic, massage, acupuncture, and homeopathy, and advice from experts in the field.
Eclectic Institute, Organic Milk Thistle, 2 fl oz (60 ml): Milk Thistle Silymarin, Homeopathy, Herbs
Most studies have investigated the isolated compound silymarin or it’s most active isomer silybin, rather than the herbal plant in it’s whole form. Evidences for antiosteoporotic and selective estrogen receptor modulator activity of silymarin compared with ethinylestradiol in ovariectomized rats. This indicates that silymarin has anti-inflammatory and antiviral effects in patients with chronic hepatitis c. Mature seeds, which have the highest level of silymarin, are found in seed heads showing abundant silvery white fluff (Pappus). Do not use ultimate herbal health products if you are allergic to any of the ingredients. Sixty women in the psychiatric ward of an italian hospital were selected for the trial, all having been treated with either phenothiazines and/or butyrophenones for at least five years. Although milk thistle has not significantly altered the course of chronic liver disease, it has reduced liver enzyme levels and demonstrated anti-inflammatory and t cell-modulating effects. The oldest reported use of milk thistle was by dioscorides (A.
Laboratory data suggest that silymarin and silybin protect the liver from damage induced by toxic chemicals. A few trials have looked at milk thistle for people with cancer. Breeding programs are working to standardize the ripening time of milk thistle while increasing the natural levels of silymarin. The aim was to see if the silymarin gel could help prevent radiodermatitis (Sore, inflammed skin caused by radiotherapy). The hepatoprotective activity of s5 was similar to the standard hepatoprotective drug silymarin and livome effects are more significant than the standard hepatoprotective drug silymarin. Neopterin, a marker of cellular immune system activation, and tnf-alpha were decreased in both groups after silymarin therapy, whereas production of interferon-gamma and il-4 were increased. Glucose (Re)absorption is viewed as an alternative way to lower blood glucose level. Zi x, mukhtar h, agarwal r: Novel cancer chemopreventive effects of a flavonoid antioxidant silymarin: Inhibition of mrna expression of an endogenous tumor promoter tnf alpha. No significant adverse effects were associated with silymarin. The difference between these potencies is in their action rather than the notion of being a stronger or weaker medicine.
Several studies have suggested that milk thistle may be beneficial for people with diabetes, most notably in those with type 2 diabetes. Agency for healthcare research and quality (Ahrq), milk thistle improved liver function in people with mild liver disease, but was less effective for those with severe liver disease, such as cirrhosis. Clinical studies suggest or confirm the efficacy of milk thistle extract for various hepatic disorders, including hepatitis a, alcoholic cirrhosis, and exposure to hazardous chemicals. Patients were randomly assigned to also receive silymarin 140 mg 3 times daily or placebo. Rare cases of milk thistle producing a laxative effect have been reported. Salmi ha, sarna s: Effect of silymarin on chemical, functional, and morphological alterations of the liver. Different parts of the milk thistle plant may be used to treat various health conditions. Some evidence exists about the positive impact of these milk thistle compounds on bone density in rats and mice that have undergone ovariectomy. Its herbal remedy is known as milk thistle extract. The most common use of milk thistle is for liver problems. However, there are currently no human studies examining the effects of milk thistle in people with alzheimer’s or other neurological conditions like dementia and parkinson’s.
70% Of the extract weight such that a 200 mg tablet contains 140 mg of silymarin, or 200 – 400 mg per daily dose. These findings suggest that silymarin plays a prominent role in the reduction of cancer cells and in preventing the formation of cancer cells. El-shitany na, hegazy s, el-desoky k: Evidences for antiosteoporotic and selective estrogen receptor modulator activity of silymarin compared with ethinylestradiol in ovariectomized rats. According to the survey, people with hepatitis c reported fewer symptoms and a somewhat better quality of life when taking milk thistle despite having no measurable change in viral activity or liver inflammation. One source suggests daily doses of 12 to 15 g of dry fruits for dyspepsia and disorders of the biliary system, while an extract containing 200 to 400 mg/day of silymarin is considered effective in various liver disorders. An additional useful source for information on some otc supplements and herbs is the national library of medicine. In patients with hepatitis c, beneficial effects have not been noted with use of silymarin. Mechanisms underlying herbal therapies using antidiabetic plants and phytocompounds. The use of silymarin in the treatment of liver diseases. Caution and close monitoring is warranted if using these agents concomitantly with milk thistle. In this review, the antidiabetic potential of the selected glucose-lowering herbs and their different mechanisms of action were summarized and discussed.
Eclectic Institute Milk Thistle Silymarin
Specifically, silymarin has been shown to stimulate the glutathione s-transferase pathway and alter the intracellular concentration of glutathione (A potent antioxidant). Most clinical trials of milk thistle have been conducted in patients with either hepatitis or cirrhosis. It also looks at how to use milk thistle and whether there are any risks to consider. One of milk thistle’s other names, marian thistle, as well as the species name, mariannum, are derived from the name mary. There is evidence of genetic differences between populations of milk thistle with regard to the content of silymarin. The active ingredients in milk thistle seeds (Actually the achenes) are a group of related flavonolignan compounds collectively referred to as silymarin. The commission e approved uses and the subsequent use of milk thistle standardized extracts in the united states are based on a significant amount of chemical, pharmacological, and clinical research. Treatment of chronic liver diseases with traditional chinese medicine. Given these contradictions, many scientists believe that milk thistle delivers something of a placebo effect in which a person feels an improvement in symptoms despite having no change in their clinical condition.
If drinking milk thistle tea, it is best to limit intake to 6 cups a day. Conditions such as rainfall and average temperature also affect silymarin production, with higher temperatures and drier conditions apparently increasing production. In laboratory studies, silymarin has been found to stabilize cell membranes, thus preventing toxic chemicals from entering the cell. Summary the active ingredients in milk thistle have been shown in animals to improve the effects of some cancer treatments. If you have liver disease, do not take any over-the-counter medication, herbs, or supplements without checking with your doctor first. The summary includes a brief history of milk thistle, a review of the laboratory studies and clinical trials, and a description of adverse effects associated with milk thistle use. In the eclectic medicine movement (19Th to 20th century), milk thistle was used to treat varicose veins, menstrual difficulty, and congestion in the liver, spleen, and kidneys. Researchers have found that milk thistle can actually prevent or reduce medication induced liver damage.
An early study from finland found that a four-week course of silymarin supplements lowered key liver enzymes in people with subacute disease, suggesting the liver was functioning more normally. A case report from australia described a reaction to a milk thistle extract that included intermittent episodes of sweating, abdominal cramping, nausea, vomiting, diarrhea, and weakness. Based on safety and their multiple targeting actions, herbal therapies are potent therapeutic means in t2d. A level of evidence score cannot be assigned to milk thistle because there has been insufficient clinical research to date. In ovariectomized rats, treatment for 12 weeks with silymarin prevented bone loss, either through increasing formation via an effect on calcium, phosphorus, osteocalcin, and parathyroid hormone, or through direct action with estrogen receptor-beta. Collectively, these findings suggest that mate and probably it’s active compounds act as an antidiabetic medicine through augmentation of glp-1 production. Women who have hormone-sensitive conditions (Such as fibroids, endometriosis, and cancer of the breast, uterus, or ovaries) should avoid silymarin extracts from milk thistle, however, if the extract is made using the seeds then it is considered to be safe for these conditions. Zi x, feyes dk, agarwal r: Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells mda-mb 468: Induction of g1 arrest through an increase in cip1/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins.
In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. Iron/copper-containing supplements: Data are mixed regarding milk thistle’s ability to chelate iron and copper. This pdq cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of milk thistle in the treatment of people with cancer. Results: In traditional medicine, silybum marianum has been introduced as harshfe barry and uses for the treatment of liver, gallbladder, and skin diseases, swelling, and strengthening digestion; today, in many studies, the effects of this plant have been studied, and properties, such as treatment of liver, kidney, and skin diseases, blood glucose control and lipid metabolism, strengthening the immune system and it’s anticancer effects have been proven. Share on pinterest milk thistle is available in a range of forms, and is most popular as a supplement or in tea. Talk to your doctor before taking any herb or supplement if you have liver disease. The milk thistle of commerce is a standardized preparation extracted from the fruits (Seeds) of silybum marianum (L).