LifeTime Vitamins, Milk Thistle Extract, 250 mg, 60 Capsules

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Product name: LifeTime Vitamins, Milk Thistle Extract, 250 mg, 60 Capsules
Quantity: 60 Count, 0.16 kg, 5.6 x 9.9 x 5.6 cm
Categories: LifeTime Vitamins, Herbs, Homeopathy, Milk Thistle Silymarin

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Researchers have found that milk thistle can actually prevent or reduce medication induced liver damage. In different countries and areas of the world, traditional medicine has been and is still used for the treatment of various disorders, including chest pain or liver complaints, of which we now know that they can be linked with altered lipid and cholesterol homeostasis. Further research on humans is needed to identify what benefits a person can expect from applying milk thistle to their skin. Of the 170 patients, 87 received 420 mg of silymarin daily, compared with 83 placebo patients. Complementary and alternative medicine in hepatology: Review of the evidence of efficacy. Chinese medicinal herbs for asymptomatic carriers of hepatitis b. In follow-up, silymarin use was associated with reduced progression of fibrosis to cirrhosis but without an impact on clinical outcome. During radiation therapy, scores significantly increased in both the silymarin and placebo groups, but the silymarin group experienced a delay in the development and progression of oral mucositis. This information relates to an herbal, vitamin, mineral or other dietary supplement.

LifeTime Vitamins, Milk Thistle Extract, 250 mg, 60 Capsules: Milk Thistle Silymarin, Homeopathy, Herbs

The use of herbs is a time-honored approach to strengthening the body and treating disease. Oral consumption of milk thistle (Standardized to 70% to 80% silymarin) at 420 mg/day is considered safe for up to 41 months based on clinical trial data. Curcumin is a major constituent of the rhizomatous powder of turmeric (Curcuma longa) and is commonly used as food and medicine in southern asia. One study in breast cancer patients, looked at applying silymarin gel to the skin on the chest wall following a mastectomy and during radiotherapy treatment. In fact, a survey funded by the national institutes of health reported that 23 percent of 1,145 people with hepatitis c used herbal supplements, with milk thistle being by far the most common. Pets suffering from diabetes that are given milk thistle at least once per week have been shown to not have to have nearly the amount of insulin that they would have had to take otherwise. Fewer chemotherapy dose reductions were observed in the silymarin group compared with the placebo group; however, the difference was not significant. However, when silymarin was combined with these agents, serum indices and hepatic markers were reduced. Pilosa is used as an herbal medicine for a variety of diseases. Women who have hormone-sensitive conditions (Such as fibroids, endometriosis, and cancer of the breast, uterus, or ovaries) should avoid silymarin extracts from milk thistle, however, if the extract is made using the seeds then it is considered to be safe for these conditions.

Most studies have investigated the isolated compound silymarin or it’s most active isomer silybin, rather than the herbal plant in it’s whole form. After three months of treatment (525 Mg/day of silymarin), chronic hepatitis was found to be significantly improved bioptically. The active ingredient in milk thistle, silymarin, acts as an antioxidant by reducing free radical production. The data is very limited, but one randomized controlled study found that mothers taking 420 mg of silymarin for 63 days produced 64% more milk than those taking a placebo. Pregnant and breastfeeding women should never take herbs or supplements unless expressly approved by their physicians. In the eclectic medicine movement (19Th to 20th century), milk thistle was used to treat varicose veins, menstrual difficulty, and congestion in the liver, spleen, and kidneys. Adding the silymarin supplement livergol to standard rheumatoid arthritis drug therapy was reported to significantly improve various disease severity parameters. A dose of 140 mg of silymarin 3 times daily has been suggested for hepatic cirrhosis.

Some animal studies have shown that milk thistle could be useful for reducing the side effects of cancer treatments (26, 27, 28). Do not harvest milk thistle plants that have been exposed to pesticides or found along roadways or industrial sites. More research is needed to determine how milk thistle may be used to help fight cancer. Once the diagnosis is established, the practitioner is likely to use acupuncture, moxibustion (A burning of an herb called mugwort over acupuncture sites), and herbal remedies to address the imbalances of hepatic qi (Energy) and yin yang (Balance). More research on humans is needed to confirm the effects of milk thistle on cognition. The hepatoprotectant effect of milk thistle fractions (Silymarin) is documented in other studies: These compounds can produce both a protective and curative effect on liver damage resulting from the highly toxic compounds phalloidin and alpha-amanitin (From the deathcap mushroom, a. Clearly, milk thistle has an array of positive effects throughout the body. The silymarin extracted from milk thistle is known to have antioxidant, antiviral and anti-inflammatory properties (2, 3, 4).

By monitoring enzymes indicative of liver function, the researchers found that the herbal extract did not create any improvement compared with the placebo. Raloxifene: Coadministration of milk thistle and raloxifene may lead to 4- to 5-fold increases in raloxifene systemic exposure due to inhibition of intestinal glucuronidation by silybin a and silybin b. In an investigation of the effect of a variety of flavonoids on the formation of dna damage, silymarin did not induce dna damage in colon (Caco-2) cells, hepatoma (Hepg2) cells, and human lymphocytes. Although taking milk thistle is generally considered safe, we would recommend anyone thinking of taking it to talk to their doctor first. Until more research is carried out, however, milk thistle is not recommended as the primary treatment option for liver problems. They suggest that a substance in milk thistle (Silymarin) can protect the liver from damage caused by viruses, toxins, alcohol, and certain drugs such as acetaminophen (Tylenol). This review provides a source of up-to-date information for further basic and clinical research into herbal therapy for type 2 diabetes. Given these contradictions, many scientists believe that milk thistle delivers something of a placebo effect in which a person feels an improvement in symptoms despite having no change in their clinical condition. Placebo or silymarin 420 mg/day (Given in 3 divided doses) was administered orally as adjunctive therapy to a relatively stable iron chelation regimen for 12 weeks, with a 2-week washout between treatments.

LifeTime Vitamins Milk Thistle Silymarin

The effects of silymarin in some early studies suggest that it might be helpful in preventing liver inflammation or liver cancer. More research is needed to confirm these results and the safety of milk thistle for breastfeeding mothers (38, 39, 40). Salmi ha, sarna s: Effect of silymarin on chemical, functional, and morphological alterations of the liver. Given this phytomedicine’s well established safety and it’s reasonable documentation of efficacy, future clinical use of milk thistle extract should be explored as an adjunct therapy in chemotherapy to help offset the effects of powerful and potentially hepatotoxic conventional drugs. The more commonly used milk thistle seed extracts are not known to have estrogenic effects. In a study of rats receiving ethanol during specific weeks of the gestational period, coadministration of silymarin with ethanol resulted in no deficits in spatial working memory in rats on postnatal day 60, suggesting silymarin provided a protective effect against alcohol-induced learning issues. The aim was to see if the silymarin gel could help prevent radiodermatitis (Sore, inflammed skin caused by radiotherapy). Caution should be used when coadministering iron/copper-containing supplements with milk thistle. Iron/copper-containing supplements: Data are mixed regarding milk thistle’s ability to chelate iron and copper. You will see very noticeable differences in your health when you pay attention to the foods and herbs that benefit your liver.

The usual recommended extract of milk thistle contains 70 to 80 percent silymarin. A level of evidence score cannot be assigned to milk thistle because there has been insufficient clinical research done. Clinical trials and combination therapies related to silymarin application in cancer prevention and treatment are presented as well. Although there are many reports on the use of herbals for the treatment of chronic liver diseases, most treatment trials have suffered from poor scientific design, uncertainty about the required dosage of herbals, and an insufficient number of study participants. A dose of 420 mg a day of silymarin produced a statistically significant greater decrease of gpt and got liver enzymes in the treated group than in the control. Medicinal herbs contain diverse bioactive compounds and can have multiple actions on insulin action, insulin production, or both. Other studies have investigated the use of milk thistle in patients with hyperlipidemia, diabetes, and amanita phalloides (Fr). Interestingly, one study found that people with acne who took 210 milligrams of silymarin per day for 8 weeks experienced a 53% decrease in acne lesions. While it is not without benefit, milk thistle does not appear to exert a significant effect on either liver tissues or liver function. Laboratory data suggest that silymarin and silybin protect the liver from damage induced by toxic chemicals.

However, studies are mixed as to whether milk thistle improves liver function tests or quality of life for people with chronic active hepatitis b or c. No evidence of effect on reproduction in rats has been found, and silymarin was not mutagenic in several tests. Talk to your doctor before taking any herb or supplement if you have liver disease. Women who are pregnant or breast feeding should not take this herb. A drop of mary’s milk fell, causing the distinctive white veins on the leaves of milk thistle. Sixty women in the psychiatric ward of an italian hospital were selected for the trial, all having been treated with either phenothiazines and/or butyrophenones for at least five years. This pdq cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of milk thistle in the treatment of people with cancer. A number of meta-analyses evaluating the efficacy of milk thistle in alcohol-induced and viral hepatitis have been conducted. Fortunately, research suggests that milk thistle extract not only prevents damage to the liver, but also helps repair it.

However, guinea pigs receiving ethanol plus ascorbic acid had a greater reduction in alt and ggt compared with those receiving silymarin. Some forms of hepatitis have responded to silymarin treatment. Nonsteroidal anti-inflammatory drugs (Nsaids), such as naproxen or aleve, and ibuprofen, motrin, or advil, can also damage the liver, as can some herbs and supplements. Active compounds and biological actions of antidiabetic herbs. The published data on silymarin use in children focuses on intravenous doses of 20 to 50 mg/kg of body weight for mushroom poisoning. They suggest that a substance in milk thistle (Silymarin) can protect the liver from damage caused by viruses, toxins, alcohol, and certain drugs, such as acetaminophen. Chili peppers, the fruits of the capsicum plants, are commonly used as food and medicine.