Natural Factors, Lycopene, 10 mg, 60 Softgels

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Product name: Natural Factors, Lycopene, 10 mg, 60 Softgels
Quantity: 60 Count, 0.05 kg, 5.6 x 5.6 x 9.9 cm
Categories: Natural Factors, Supplements, Antioxidants, Lycopene, Non Gmo

Dietary Supplement, Natural Tomato Lycopene, Plus Pumpkin Seed Oil, Isura – Non-GMO – Mass Spec – Documentation – Lab Tested, Purity and Potency Guaranteed, Easy-to-Swallow lycopone softgels contain 10 mg of the important carotenoid, lycopene. Derived from tomato, lycopene is responsible for the healthy red color and is more powerful free radical quencher than beta-carotene. As a potent antioxidant, lycopene helps prevent damage to cellular structures throughout the human body. Recent scientific research suggests that lycopene may be an important tool for men who want to support prostate health and for those who wish to guard against UV.

Therefore, women who might be or are pregnant should not take high doses of vitamin a supplements. Although this was a small study without a control group, the results suggest that lycopene may not be beneficial for patients with advanced prostate cancer. While the selenium supplementation did not have an effect on skin cancer, at the end of the trial, an analysis of the 457 men receiving supplementation showed a significantly lower incidence of prostate cancer than those 470 men receiving a placebo (With a mean follow-up of more than 7 years). Overall, there was more support for consuming tomato products versus taking a lycopene supplement daily for improvements in lipoproteins (E. Of the 3 trials testing lycopene supplements (74, 84, 107), Only kim et al. An association between lycopene serum concentration and risk of cancer was also examined in men participating in the kuopio ischaemic heart disease risk factor study in finland. The most well known function of vitamin e is as an antioxidant, detoxifying oxidizing radicals that arise as unwanted by-products during normal metabolism. Carotenoids in human buccal mucosa cells after 4 wk of supplementation with tomato juice or lycopene supplements. 33 Lycopene concentrations changed rapidly in men with prostate cancer given lycopene supplements for several weeks prior to radical prostatectomy.

Natural Factors, Lycopene, 10 mg, 60 Softgels: Lycopene, Antioxidants, Supplements

49 Plasma ldl cholesterol concentrations were reduced by 14% in 6 men consuming dietary supplements of lycopene 60 mg/day for a 3-month period. Excessive lycopene intake has been linked to temporary orange-hued skin discoloration called lycopenodermia, but it is not dangerous and skin color returns to normal after reduction of intake. Adding lycopene to medium containing the lncap human prostate adenocarcinoma cell line resulted in decreased dna synthesis and inhibition of androgen-receptor gene-element activity and expression. G, beta-carotene) was found, the results of this study suggested a protective role for lycopene. 25 A pooled analysis of 8 prospective studies on carotenoids and breast cancer demonstrated a statistically significant inverse association between carotenoid levels, including lycopene concentrations, and the risk of breast cancer. Vitamin e (Actually a group of 4 tocopherols and 4 tocotrienols) is the most popular supplement used by men. High-quality research on lycopene alone is needed. In an investigation by chen and coworkers, 44 32 men with prostate cancer were given dishes with tomato sauce containing 30 mg of lycopene every day for the 3 weeks leading up to prostatectomy.

The mean difference between groups who received the lycopene supplementation demonstrated a lower percentage of cells expressing ki-67, compared with the control group. 40, Giovannucci e: Tomato products, lycopene, and prostate cancer: A review of the epidemiological literature. Factors including meal composition and genetics deserve further evaluation to determine their impacts on lycopene absorption, isomerization, and biodistribution. Two other studies reported no differences in bp after lycopene supplementation at similar doses and duration (74, 130). However, when taken as a supplement, lycopene may interact with certain medications, including blood thinners and blood-pressure lowering medications. Intestinal absorption of lycopene from different matrices and interactions to other carotenoids, the lipid status, and the antioxidant capacity of human plasma. Limited research suggests that higher lycopene levels may decrease the risk of plaque build-up in the arteries. Serum and hdl fractions were enriched with lycopene compared with control after the food-based and supplement intervention. It is also a powerful biological antioxidant. Lycopene and lycopene-rich foods have been studied as a potential therapy for breast cancer. Diet and dietary supplement intervention trials for the prevention of prostate cancer recurrence: A review of the randomized controlled trial evidence.

However, it was unclear from that particular study which of the antioxidants exerted the effects seen due to the mixed nature of the active intervention. In animal studies, lycopene has been found to have antioxidant effects and may also block cancer cell growth. Over a 10-year period, researchers noted that individuals with metabolic disease who had the highest blood lycopene levels had up to a 39% lower risk of dying prematurely. 36, 37 None of the studies reported severe toxicity or intolerance related to lycopene supplementation according to national cancer institute common toxicity criteria. But randomized controlled trials of patients with advanced cancer did not find significant benefit of supplementation over placebo. 48 The austrian stroke prevention study found that certain concentrations of lycopene and other antioxidants may protect against cognitive impairment. The carotenoid, lycopene, has been found to be low in the blood of people with atherosclerosis, particularly if they are smokers. There were also instances of fetal growth problems in women having their first child after lycopene supplementation. Conversely, there are studies that suggest caution with selenium supplement usage among males with prostate cancer.

You do not sleep better, you do not feel better, in fact, there is no physical, obvious benefits at all, other than the confidence that this is a very good antioxidant, working in the background, keeping you safe from all manner of awful diseases. Compared the bioavailability of lycopene from tomato juice, tomato paste, and a lycopene tablet, each consumed with a standardized meal. Although generally regarded as safe, vitamin supplements may have harmful effects. 102 The sponsor-funded, double-blind, randomized procomb italian multicenter trial determined that the combination of saw palmetto, lycopene, selenium (Profluss) plus tamsulosin produced significantly improved prostate symptom scores and q max (Flow) after 1 year of treatment compared with profluss or tamsulosin monotherapies in 219 men with bph/lower urinary tract symptoms. 45, Boileau tw, liao z, kim s, lemeshow s, erdman jw jr, clinton sk: Prostate carcinogenesis in n-methyl-n-nitrosourea (Nmu)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. In summary, there is promising evidence for a role for both lycopene supplementation and tomato products for improvements in systolic and diastolic bp. Recent studies emphasized the cardioprotective effects of lycopene. Until concrete evidence becomes available, patients should avoid antioxidant supplements during treatment. We hypothesised that lycopene would improve endothelial function in patients with pre-existing cvd, and separately, in healthy volunteers (Hv) also.

Natural Factors Lycopene

Tomatoes provide a number of key nutrients and phytochemicals, including lycopene, that support cardiovascular health. 7 Processed tomato products are a better source of lycopene than fresh tomatoes, 8 with lycopene more bioavailable. In plants it is considered as an important intermediate of carotenoid synthesis, but in human nutrition lycopene plays no role as provitamin a precursor due to the absence of appropriate enzymes. This adds to the tally of chronic diseases that lycopene may help improve or prevent. After just four years of beta-carotene and vitamin a supplementation, there was a 28% increase in lung cancer rates and a 17% increase in those who died. Nevertheless, we have demonstrated that subjects in the lycopene group had increased their serum lycopene levels significantly in both cvd and hv arms of our trial, suggesting natural variations in dietary intake were probably minimal in our randomised trial across both lycopene and placebo groups in both arms. I take lycopene as a supplement for my high blood pressure. Do any supplements help prevent sunburn or skin damage from sun exposure? Research has shown conflicting results of lycopene intake on ovarian cancer risk.

Although lycopene seems to be the bioactive compound of major importance, there is also the possibility of a synergistic action with other compounds in tomato, especially glycoalkaloids (Tomatine), phenolic compounds (Quercetin, kaempferol, naringenin and chlorogenic acid), salicylates and carotenoids, other than lycopene (Phytoene and phytofluene), which cannot be excluded. Supplementing mice with lycopene or beta-carotene resulted in decreased tumor growth. In a placebo-controlled, double-blind, randomized study, 199 men with localized prostate cancer were randomly assigned to either a food supplement, pomi-t, or placebo (2:1) For 6 months. A recent review included a mixed supplementation study and focused on rcts only. Most lycopene supplements come somewhere in the range of 10 to 20 mg per tablet. Researchers at the kresge eye institute in detroit investigated the effect of carotenoid-containing supplements on retinal oxidative stress and inflammation and the development of diabetic retinopathy. One small study also found that 2 mg of daily lycopene supplements during pregnancy could increase your risk of preterm labor or low birth weight. Effects of watermelon supplementation on arterial stiffness and wave reflection amplitude in postmenopausal women. Of 11 clinical trials testing the effects of lycopene supplementation (Table 11), only 1 showed improvements in tc, ldl cholesterol, and hdl cholesterol, although an increase in tgs was also reported in these postmenopausal women.

It is a powerful antioxidant that can quench singlet-oxygen free radicals twice as efficiently as beta-carotene. These newspaper stories are based on the release of a new food supplement, the active ingredient of which is lycopene, a compound found in some red-skinned fruit including tomatoes. In the supplementation en vitamines et mineraux antioxydants (Su. The present review highlights the need for more targeted research; however, at present, the available trials support consuming tomato-based foods as a first-line approach compared with lycopene supplementation, with the exception of bp management. Effect of long term supplementation of tomatoes (Cooked) on levels of antioxidant enzymes, lipid peroxidation rate, lipid profile and glycated haemoglobin in type 2 diabetes mellitus. But since taking the supplement long-term is associated with cancer, pregnant women should consult with their physician before taking beta-carotene supplements (30, 31). Study participants whose diets contained the lowest amounts of foods containing natural lutein and zeaxanthin experienced the greatest amd risk reduction from taking the daily nutritional supplement.

Gnc lycopene scores well when it come to dosage, as it’s 30 mg per capsule of lycopene is pretty solid. Mild heartburn was reported in 9 of 23 subjects, but it resolved when the study supplements were taken with food. However, oral protection from sunburn is not instantaneous; maximum effects are not reached until these antioxidants have been used for about eight to ten weeks. Lycopene is an antioxidant found originally in tomatoes that can improve cardiovascular health, prevent oxidative damage and oxidative stress, treat systemic inflammation, and has even been studied as a preventative agent against prostate cancer. In addition, treating prostate cancer cells with lycopene resulted in a significant decrease in the number of lycopene-treated cells in the s phase of the cell cycle, suggesting that lycopene may lower cell proliferation by altering cell-cycle progression. Furthermore, the molecular mechanisms behind the actions of lycopene on human rpe cells, and the potential beneficial effects of lycopene in the prevention and treatment of age-related macular degeneration and proliferative vitreoretinopathy, are discussed. Some evidence suggests that diets high in lycopene may reduce the risk of certain cancers and have heart-health benefits, such as lowering cholesterol. Little is known with regard to the biology of dietary lycopene in the human body.

Tomato consumption and plasma lycopene concentration in people aged 65 y and over in a british national survey.