Product name: Nature’s Bounty, Milk Thistle, 1000 mg, 50 Rapid Release Softgels
Quantity: 50 Count, 0.07 kg, 5.1 x 5.1 x 10.7 cm
Categories: Nature’s Bounty, Herbs, Homeopathy, Milk Thistle Silymarin, Laboratory Tested
Concentrated Health, Herbal Health, Herbal Supplement, Guaranteed Quality, Laboratory Tested, Over 40 years of Trusted Quality, At Nature’s Bounty, we are committed to your health. For over 40 years we have been making trusted products, backed by science, and made with only the purest ingredients. guaranteed. So you can get the most out of life every day.
Based on safety and their multiple targeting actions, herbal therapies are potent therapeutic means in t2d. People with ragweed allergies may be more likely than others to be allergic to milk thistle. When reported, side effects for milk thistle are generally gut disturbances like diarrhea, nausea or bloating. Constituents of note: Silymarin is the well-known component in the seeds, believed to play the major role in the action of milk thistle. Conclusion: The results of this study showed that some of the properties of milk thistle, such as protection and the treatment of liver diseases, treatment of skin disorders, and anticancer effects that have been proven in recent studies are referred to in traditional medicine texts; therefore, it seems that traditional medicine combinations can be useful in modern medical interventions. However, there are currently no human studies examining the effects of milk thistle in people with alzheimer’s or other neurological conditions like dementia and parkinson’s. Ultimate herbal health products comply with the dietary supplement laws in new zealand. The active constituent of milk thistle is silymarin, which is a complex mixture of flavonoids and flavonoid derivatives, the flavonolignans. The active constituents of this herb such as flavonoids and caffeoylquinic acid may be responsible for this effect. Other substances in milk thistle have not been extensively studied.
Nature’s Bounty, Milk Thistle, 1000 mg, 50 Rapid Release Softgels: Milk Thistle Silymarin, Homeopathy, Herbs
However, at least two articles in major journals have suggested that silymarin or it’s congeners may inhibit hcv. Powdered milk thistle can be made into a tea. The use of a medicinal herb, alone or in combination with other herbs, can be thought of as a type of combination therapy because of the complexity of the phytochemicals and bioactivities in the plant. Several in vitro studies have explored anticancer effects of milk thistle extracts. Dry extract 40-70:1 (W/w), 70-80% silymarin: Swallow one capsule containing 100-200 mg of silymarin, twice daily in the morning and evening. These three herbs are just the beginning. Cordyceps (Cordyceps sinensis): Is a type of mushroom used in traditional chinese medicine to support the liver. We use a triple percolation process which creates, without heat, a more concentrated extract which contains the full-spectrum of milk thistle’s silymarin flavonoids silybin, silydianin and amp; silychristin. Ultimate herbal health products should not be used by pregnant or nursing women, by children under 12, or by anyone with a serious medical condition. So people with a history of hormone-sensitive conditions should use milk thistle with caution. Gluten-free and vegetarian: Our standardized milk thistle is gluten free and vegetarian, made with plant-derived capsules. More than 60 natural compounds from traditional medicine, especially traditional chinese medicine (Tcm), are reported to regulate abca1 expression in different in vitro and in vivo models (Such as cholesterol efflux and atherosclerotic animal models).
It’s naturally present in the seeds at 1 to 5%, but standardized extracts and formulations are often concentrated, so they contain 70 to 80% silymarin. Though studies in the lab have shown that milk thistle may protect and promote the growth of liver cells, clinical trials have been mixed at best, and many of the studies have not been well designed. In the eclectic medicine movement (19Th to 20th century), milk thistle was used to treat varicose veins, menstrual difficulty, and congestion in the liver, spleen, and kidneys. Most clinical trials of milk thistle have been conducted in patients with either hepatitis or cirrhosis. Sjw is a flowering herb that may have antidepressant properties; it is commonly used in europe, particularly in germany. A case report from australia described a reaction to a milk thistle extract that included intermittent episodes of sweating, abdominal cramping, nausea, vomiting, diarrhea, and weakness. It’s seeds are used as a chinese herbal medicine for pain, gastrointestinal diseases, and others. The effects of silymarin in some early studies suggest that it might be helpful in preventing liver inflammation or liver cancer.
If there has been kidney damage to your pet because of an infection milk thistle has been show to greatly decrease the amount of time it takes your pet to heal. The hepatoprotectant effect of milk thistle fractions (Silymarin) is documented in other studies: These compounds can produce both a protective and curative effect on liver damage resulting from the highly toxic compounds phalloidin and alpha-amanitin (From the deathcap mushroom, a. In vitro studies show that silymarin decreases the components of the cytochrome p450 enzyme system, which is involved in the clearance of certain chemotherapy drugs. An adverse reaction to the herbal medication milk thistle (Silybum marianum). To be honest i cannot tell the difference between this and the milk thistle i was buying on the uk high street – except this one is about a quarter of the price – even when that high street giant is having one of it’s regular special offer sales! To find a holistic or homeopathic vet near you or to find one who will do phone consultations, visit the academy of veterinary homeopathy. Caution and close monitoring is warranted if using these agents concomitantly with milk thistle. Complementary and alternative medicine in chronic liver disease. According to the survey, people with hepatitis c reported fewer symptoms and a somewhat better quality of life when taking milk thistle despite having no measurable change in viral activity or liver inflammation.
More clinical trials of rigorous methodology, using standardized and well-defined products and dosages, are needed to evaluate the potential of silymarin against liver toxicity, chronic liver disease, and human cancers. You can find milk thistle in most health food stores or health sections of your local grocery store. Complementary and alternative medicine in hepatology: Review of the evidence of efficacy. The ancient greek and romans used milk thistle for snake bites. Mechanisms underlying herbal therapies using antidiabetic plants and phytocompounds. Silymarin/ silybum (Milk thistle) milk thistle heals hepatitis, cirrhosis and reverses liver damage. I detoxed for heavy metals about 10 years ago to get rid of osteoporosis and use products like milk thistle to keep my liver detoxed. German pharmacopeial grade milk thistle also consists of the ripe fruit with the pappus removed. One study investigated the effects of silymarin on the pharmacokinetics of irinotecan. Although it is possible that milk thistle may play a part in treating liver disease and some types of cancer there is currently not enough evidence for this. In an investigation of the effect of a variety of flavonoids on the formation of dna damage, silymarin did not induce dna damage in colon (Caco-2) cells, hepatoma (Hepg2) cells, and human lymphocytes. Patients either had the silymarin gel or a placebo gel starting on the first day of radiotherapy treatment and continuing for the full 5 weeks of treatment.
Nature’s Bounty Milk Thistle Silymarin
In a pilot, randomized, double-blind, placebo-controlled clinical trial, hospitalized patients receiving cisplatin were administered placebo or oral silymarin 420 mg/day in 3 divided doses starting 1 to 2 days prior to cisplatin initiation and continuing through the end of 3 cycles of 21-day chemotherapy. Its herbal remedy is known as milk thistle extract. However, studies on the milk thistle’s effectiveness in treating liver disorders have yielded mixed results. Studies have shown improvements in liver function in people with liver diseases who have taken a milk thistle supplement, suggesting it could help reduce liver inflammation and liver damage. Researchers have found that milk thistle can actually prevent or reduce medication induced liver damage. While there are numerous other constituents with known pharmacological activity, such as quercetin, the extract of milk thistle achenes is standardized for quality control on the content of silymarin, e. Interestingly, one study found that people with acne who took 210 milligrams of silymarin per day for 8 weeks experienced a 53% decrease in acne lesions. Additionally, varicocelized rats receiving silymarin had higher testosterone levels and a larger percentage of sperm with nuclear maturity compared with varicocelized rats not receiving treatment. Mature seeds, which have the highest level of silymarin, are found in seed heads showing abundant silvery white fluff (Pappus).
This indicates that silymarin has anti-inflammatory and antiviral effects in patients with chronic hepatitis c. She recalled taking milk thistle for headaches and liver cleansing for about 2 months. Toxic effects of silymarin have not been noted clinically at a dosage of 1,200 mg/day; however, mild allergies have been reported with dosages greater than 1,500 mg/day. The active ingredients in milk thistle are a group of plant compounds collectively known as silymarin. Mucositis scores (World health organization, national cancer institute common toxicity criteria) were significantly lower in the silymarin group. The tincture should be bright yellow, indicating the presence of the resinous fraction which contains the silymarin. Milk thistle is an herbal remedy derived from the milk thistle plant, also known as silybum marianum. The use of herbs is a time-honored approach to strengthening the body and treating disease. One study in breast cancer patients, looked at applying silymarin gel to the skin on the chest wall following a mastectomy and during radiotherapy treatment. The standard dosage of milk thistle extract is based on a silymarin content of around 80 percent; most supplements contain anywhere from 50-500 milligrams (175 Mg is typical).
It has been used as a medicine for over 2,000 years as milk stimulant, for liver, kidney and spleen problems, for jaundice, gall stones, and menstrual pain. While moderate use of milk thistle is very safe, there is some experimental evidence to suggest that long-term ingestion of very high dosages of milk thistle will eventually suppress liver function. Poisoning suggests that silymarin has been shown to be an effective drug in the treatment of this mushroom poisoning. To avoid complications, always advise your doctor about any supplements or herbal remedies you are taking. Raloxifene: Coadministration of milk thistle and raloxifene may lead to 4- to 5-fold increases in raloxifene systemic exposure due to inhibition of intestinal glucuronidation by silybin a and silybin b. Alternatively, this may be related to the effect of silymarin on detoxification systems. Simeprevir: Concomitant use of simeprevir with milk thistle may result in increased plasma concentrations of simeprevir. A statistical analysis showed a difference between got and bilirubin values in the silymarin and placebo groups, with a regression of gpt values in favor of silymarin.
At the end of radiation therapy, 23,5% of the women in the silymarin-based study group developed no skin reactions compared with 2% of the women in the soc group, while grade 3 toxicity occurred in only 2% of women in the silymarin-based group and in 28% of women in the soc group. (B) the selected plants and compounds exert their antihyperglycemic effect through targeting one single mechanism (Insulin resistance (Type 1 herbs), -cell function (Type 2 herbs), glp-1 (Type 3 herbs), or glucose (Re)absorption (Type 4 herbs)) or multiple mechanisms.