Product name: Now Foods, Lycopene, 20 mg, 50 Softgels
Quantity: 50 Count, 0.07 kg, 8.9 x 4.8 x 4.8 cm
Categories: Now Foods, Supplements, Antioxidants, Lycopene, Non Gmo, Gmp Quality Assured, Produced In A Gmp Certified Facility
Free Radical Scavenger, Supports Vascular Health, Natural Extract From Tomatoes, Lyc-O-Mato – Natural Lycopene Complex, A Dietary Supplement, Non-GMO, General Health, Family Owned Since 1968, GMP Quality Assured, NOW Lycopene features Lyc-O-Mato, patented tomato complex with a full complement of tomato phytonutrients, including natural Lycopene. Natural Lycopene is known for its powerful free radical scavenging properties. Clinical studies indicate that Lycopene helps to support cardiovascular health and normal immune system function. In addition, Lycopene may aid in the maintenance of a healthy prostate.
The body utilizes lycopene in supplements about as easily as that in food. Lycopene is still needed in my diet (I’m italian and could die without it) so i went with this supplement. One trial reported a cancer-related hemorrhage in a patient taking lycopene, but causality was unclear. There was no significant difference at week 12 between the lactolycopene and placebo treatment arms for any of the semen quality parameters measured (P values not shown in table, all exceed 0,05; ns). 1 These studies suggest that the lycopene present in tomato juice is poorly absorbed. Future cardiovascular disease prevention strategies might include lycopene-enriched products, lycopene supplementation and new combinations including lycopene. Most of the studies considered only tomatoes and tomato products as lycopene source. Lycopene supplementation improves endothelial function in cvd patients on optimal secondary prevention, but not in hvs. Many studies suggest that complementary and alternative medicine (Cam) use is common among prostate cancer patients, and the use of vitamins, supplements, and specific foods is frequently reported by these patients. Lycopene is a particularly good supplement choice for men, because they are obviously at risk for prostate cancer, and in addition, men have a higher rate of cardiovascular disease than women. Higher dietary levels of antioxidant vitamins and minerals may reduce the risk of progression of age-related macular degeneration (Amd).
Now Foods, Lycopene, 20 mg, 50 Softgels: Lycopene, Antioxidants, Supplements
Selenium supplementation was well tolerated in many clinical trials. Epidemiological studies have demonstrated that populations with high intake of dietary lycopene have lower risk of prostate cancer. Lycopene bioavailability in supplemental form has not been as extensively studied and remains an important area for research. The antioxidative power of lycopene may prevent prostate cancer. However, there are so many potential causes for these conditions that it is impossible to definitively associate them with a lycopene deficiency. Small studies suggest that lycopene supplements may be helpful in men with prostate cancer and for male infertility. I take lycopene as a supplement for my high blood pressure. Although lycopene is believed to have antioxidant benefits, research has found mixed results in this area. Plasma lycopene increased from baseline to the end of treatment in all treatment groups, with the greatest increase observed in the 45 mg lycopene-supplemented arm. For example, a cup of fresh strawberries contains about 80 mg of vitamin c, a nutrient classified as having high antioxidant activity. Pooled data as well as subgroup analysis (Ie, study design, smoking history, alcohol consumption, gender, geographical location) revealed no significant association between consumption of lycopene and the risk of colorectal cancer.
Foods and supplements are sources, which provide vitamin c intake while that from foods only is referred to as dietary vitamin c. The mechanisms underlying this effect are unclear but may be partly due to a high antioxidant component of the diet. However, taking antioxidant supplements in high amounts can do just the opposite. Clinical trials evaluating isoflavones, soy supplements, and soy products (Refer to table 4 and table 5) for treating localized prostate cancer before radical prostatectomy have used window-of-opportunity trial designs (From biopsy to prostatectomy). Zyflamend and the additional dietary supplements were well tolerated by the patients, and no serious adverse events occurred. In addition, treating prostate cancer cells with lycopene resulted in a significant decrease in the number of lycopene-treated cells in the s phase of the cell cycle, suggesting that lycopene may lower cell proliferation by altering cell-cycle progression. The increase in serum lycopene in associated with the reduction in prostate-specific antigen(Psa)and a decrease in tumor size shown with daily lycopene supplementation. High-quality studies on the use of lycopene supplementation for kidney disorders or kidney cancer are lacking. Early research has found inconsistent results for using lycopene to prevent high blood pressure in pregnancy. Lycopene antioxidant and biological effects and it’s bioavailability in the human.
Cambridge nutraceuticals ltd funded half of the running costs for this trial and also provided the lactolycopene and placebo treatments free of charge. However, there is not enough evidence to say that lycopene provides such health benefits. Large amounts of the carotenoid lycopene have been shown to increase the activity of natural killer cells in the elderly. Comparison of lycopene and tomato effects on biomarkers of oxidative stress in vitamin e deficient rats. Several studies have examined the role of dietary factors and data from randomized controlled trials suggest that oral antioxidant therapy can improve some sperm parameters. Secondary outcomes included forearm responses to sodium nitroprusside (Snp; measuring vascular smooth muscle sensitivity) and n g-monomethyl-l-arginine (L-nmma; measuring basal no synthase activity) infusion, arterial stiffness, blood pressure, serum lycopene concentrations, and safety and tolerability parameters. Research has looked at lycopene levels in the body or focused on tomatoes or tomato-based products, rather than on lycopene supplements. Health benefits of lycopene supplementation have been proposed for a variety of health conditions and here we examine whether it can help improve sperm quality. Potentiation of the retinoic acid-induced differentiation of hl-60 cells by lycopene. Several studies have shown that antioxidants through diet help people’s immune systems, protect against free radicals, and lower the risk of developing cancer and heart disease.
The ability of antioxidants to combat free radicals strengthens the immune system to identify and fight toxins. Additional research of lycopene alone is needed to draw conclusions. The authors reported no statistically significant association between selenium supplement use and biochemical recurrence, cardiovascular disease mortality, or overall mortality. In the united states, it is sold as a dietary supplement, usually as 50-mg tablets. This article looks at the health benefits and top food sources of lycopene. Once inside the enterocyte, lycopene is packaged with other dietary lipids into chylomicrons and released into the lymphatic system for transport to the liver. It did not find that antioxidant supplements of vitamin e or selenium, alone or in combination, protected against dementia compared with a placebo. Men who wish to supplement this nutrient may benefit more from a whole-food tomato concentrate than from isolated lycopene. A multicenter 10-country european trial also showed that lycopene can reduce the risk of myocardial infarction. I take this along with a few other supplements for prostate health and blood flow, such as jarrow’s acetyl-l-carnitine arginate and alpha lipoic acid, vitamin d3, and thorne’s basic b as well as additional p5p (Aka methylated vitamin b6). When asked to list your medications, include all vitamins, supplements, and over the counter medications.
Now Foods Lycopene
Athletes and gym-goers who took antioxidant supplements to fight the extra free radicals produced by the body during exercise prevented their bodies from receiving the full health benefits of exercise. In an unblinded, controlled trial, lycopene supplementation, but not tomato juice, effectively increased the body’s lycopene stores. 15 The researchers evaluated the blood enzymatic antioxidant system, including glutathione and selenium concentrations. The duration of supplementation and follow-up ranged from nine months to six years; one trial followed up beyond two years. We noted a small decrease in diastolic bp in lycopene treated cvd patients that was not significant when placebo corrected. Overall, a varied and balanced diet that includes antioxidant-rich foods and drinks (E. This systematic review was undertaken to evaluate existing evidence for a protective effect of lycopene/tomato-based supplementation on post-diagnostic progression of prostate cancer in order to provide evidence-based recommendations for prostate cancer patients and their clinicians. Lycopene has a chemopreventive effect against prostate cancer but it’s role in prostate cancer progression is unknown; many patients increase their intake of lycopene, although there are no evidence-based guidelines to suggest an effect.
Compliance with the intervention was good and similar in both treatment arms, with median compliance of 97,6% and 94,3% in the placebo and lactolycopene arms, respectively (Table 1). We were able to demonstrate a 53% improvement in ach responses post-lycopene therapy in cvd patients (Who were impaired at baseline), but not hvs. As of the last update, we found no reported interactions between this supplement and medicines. In 1 study, lycopene inhibited human colon carcinoma, myeloid leukemia, and lymphoma cell lines in a dose-dependent manner. Two other studies reported no differences in bp after lycopene supplementation at similar doses and duration (74, 130). Effect of long term supplementation of tomatoes (Cooked) on levels of antioxidant enzymes, lipid peroxidation rate, lipid profile and glycated haemoglobin in type 2 diabetes mellitus. Indeed, future research that is well designed, clinically focused, mechanistically revealing, and relevant to human intake will undoubtedly add to the growing body of knowledge unveiling the promise of tomatoes and/or lycopene supplementation as an integral component of a heart-healthy diet. The study found that both people who were healthy and those with diseases taking beta-carotene and vitamin e supplements had a higher rate of death. Due to the lack of a beta ring in the chemical structure of lycopene, it is not a vitamin a precursor. Some studies on tomato intake, lycopene levels, and disease risk suggest benefit with lycopene intake.
Summary diets rich in the antioxidant lycopene may help prevent the development of prostate cancer. Some people have developed allergic skin reactions such as rashes from lycopene. There is no basis, the authors write, for manufacturers to make health claims for lycopene as a food ingredient or a dietary supplement, and they said claims about the effect of tomatoes on prostate, ovarian, gastric and pancreatic cancer should be qualified by noting that such assertions are unlikely, uncertain or lacking in scientific evidence. Since antioxidants neutralize free radicals, taking antioxidant supplements have been speculated to decrease the risk of developing or dying from cancer. Studies suggest that vitamin c’s antioxidant mechanisms may help to prevent cancer in several ways. However, it was unclear from that particular study which of the antioxidants exerted the effects seen due to the mixed nature of the active intervention. Although beneficial, lycopene is not considered an essential nutrient for humans.
Unlike other fruits and vegetables, where nutritional content such as vitamin c is diminished upon cooking, processing of tomatoes increases the concentration of bioavailable lycopene. Not that he suggested this, he recommended a prescription vitamin pill, but the main ingredient is lycopene.