Product name: Now Foods, Lycopene, 10 mg, 60 Softgels
Quantity: 60 Count, 0.07 kg, 5.1 x 5.1 x 10.7 cm
Categories: Now Foods, Supplements, Antioxidants, Lycopene, Non Gmo, Gmp Quality Assured, Produced In A Gmp Certified Facility
Free Radical Scavenger, Supports Vascular Health, Natural Extract From Tomatoes, Lyc-O-Mato – Natural Lycopene Complex, A Dietary Supplement, Non-GMO, General Health, Family Owned Since 1968, GMP Quality Assured, NOW Lycopene features Lyc-O-Mato patented tomato complex with a full complement of tomato phytonutrients, including natural Lycopene. Natural Lycopene is known for its powerful free radical scavenging properties. Clinical studies indicate that Lycopene helps to support cardiovascular health and normal immune system function. In addition, Lycopene may aid in the maintenance of a healthy prostate.
As a dietary supplement, one capsule daily, preferably with a meal. Also, remember that individuals sometimes react differently to certain supplements, which can have unintended effects such as adverse reactions with medications. We were able to demonstrate a 53% improvement in ach responses post-lycopene therapy in cvd patients (Who were impaired at baseline), but not hvs. The researchers found that people who had the greatest estimated intake of lycopene had a 23% lower risk of prostate cancer compared to those with the lowest intake. There were six cohorts in the study, each receiving a different dose of lycopene (15, 30, 45, 60, 90, Or 120 mg/d). 87 Pharmacokinetic parameters of lycopene have been evaluated in humans. The three categories were combined in an attempt to cover as many variations as possible for (I) prostate cancer, (Ii) lycopene and (Iii) progression. Although there was evidence of lycopene and fatty deposits in the liver, there was no measurable liver damage. A major question, however, is whether lycopene as a dietary supplement can deliver cardiovascular benefits equivalent to tomatoes.
Now Foods, Lycopene, 10 mg, 60 Softgels: Lycopene, Antioxidants, Supplements
This information relates to an herbal, vitamin, mineral or other dietary supplement. Each type of dietary supplement or food will have a dedicated section in the summary, and new topics will be added over time. 38 As these studies did not include a control group, these effects cannot be definitely ascribed to lycopene use. Patients may be frustrated when asked to stop taking their trusted supplements. The aa genotype has been associated with more aggressive prostate cancer and with more sensitivity to antioxidants than the va or vv genotype. Many questions remain unanswered, including which patient group may be most likely to benefit from lycopene supplementation, and what are the most appropriate dose, duration and methods of supplementation. Lipid profile, antioxidant status, psa, and igf-1 were not modified by consumption of tomato pastes and lycopene. How do nutritional and hormonal status modify the bioavailability, uptake, and distribution of different isomers of lycopene? Men with a strong family history of prostate cancer should undergo genetic testing, to identify antioxidant gene mutations that may be implicated in prostate cancer. Many studies suggest that complementary and alternative medicine (Cam) use is common among prostate cancer patients, and the use of vitamins, supplements, and specific foods is frequently reported by these patients.
Not that he suggested this, he recommended a prescription vitamin pill, but the main ingredient is lycopene. This adds to the tally of chronic diseases that lycopene may help improve or prevent. Adding lycopene to medium containing the lncap human prostate adenocarcinoma cell line resulted in decreased dna synthesis and inhibition of androgen-receptor gene-element activity and expression. Overall, there seems to be a modest benefit in consuming tomato products versus taking a lycopene supplement daily on measures of oxidized ldls; however, the benefit appears to be confined to relatively healthy, nonsmoking individuals. More information is needed to assess the effects of lycopene on these conditions. Lycopene is an example of a lipid-soluble (Hydrophobic) compound with in vitro antioxidant properties that can be obtained from food or supplements. Coenzyme q 10 (Coq10), or ubiquinone, is essentially a vitamin or vitamin-like substance. We did not observe any effect of lycopene on systemic markers of inflammation (Hscrp, cytokine profile), bp, or arterial stiffness. 95, 96 The amount of lycopene in foods is assumed to be safe. Perhaps, future clinical trials should include longer duration of consistent lycopene exposure, while accounting for variations in individual absorption of carotenoids and heterogeneity of high-risk (Hgpin, atypical small acinar proliferation) and prostate cancer patient populations (Indolent vs.
No association was found between lycopene levels and prostate cancer risk. 9 In addition, human uptake of lycopene is greater from heat-processed tomato juice than from unprocessed tomato juice. I like that the separate supplements for prostrate that i was giving my dad can be found in one bottle. The review, published online july 10 in the journal of the national cancer institute, examined 81 studies of lycopene and concluded that none produced any credible evidence to support a relationship between consumption of the antioxidant either in food or dietary supplements, and the risk for prostate, lung, colorectal, gastric, breast, ovarian, endometrial or pancreatic cancer. Very little is known about the in vivo metabolism of lycopene. Consumerlab tested and reviewed popular lycopene supplements. Other lycopene products i have taken have a distinctive concentrated tomato taste and colour. Athletes and gym-goers who took antioxidant supplements to fight the extra free radicals produced by the body during exercise prevented their bodies from receiving the full health benefits of exercise. I take lycopene as a supplement for my high blood pressure.
Elimination of 1 study with wide confidence intervals revealed a significant inverse association between dietary intake as well as blood concentrations of lycopene and prostate cancer risk. They are white, not red, not sure why they are not red but i take the manufacturers at their word and swallow them, expecting all the benefits of this supplement. Do any supplements help with gum disease or periodontitis? The bioavailability of lycopene varies according to the preparation of tomatoes (Puree, ketchup etc), as well as it’s origin, size, shape, and the manner in which it is consumed (Very bioavailable in the presence of oil, for instance). Post-treatment) showed a median increase after supplementation for 174 days; however, this was not statistically significant. Consult with your physician or eye doctor before trying any vision supplements. Cis-trans isomers of lycopene and beta-carotene in human serum and tissues. Future studies should focus on men from infertile partnerships to determine not only the optimum dose and timing of lycopene both to improve sperm quality but also whether this enhances pregnancy outcome for these couples. Effects of lycopene supplementation in patients with localized prostate cancer. Research suggests that lycopene may have antioxidant benefits. I like this formula because in addition to saw palmetto, pygeum, and lycopene, it has a balanced dose of zinc and copper, which are also important for prostate health.
Now Foods Lycopene
In 1 study, lycopene inhibited human colon carcinoma, myeloid leukemia, and lymphoma cell lines in a dose-dependent manner. The lactolycopene supplement was manufactured and provided by cambridge nutraceuticals ltd. You will get results for 11 lycopene supplements – eight selected by consumerlab and three others that passed the same testing through our voluntary quality certification program. These antioxidants can be found in vitamins a, c and e, in the minerals selenium, zinc and copper, and can also be found in phytochemicals from plants, fruits and vegetables. In this prospective cohort study, an inverse association between lycopene levels and overall cancer risk was observed, suggesting that higher concentrations of lycopene may help lower cancer risk overall. Effect of tomato product consumption on the plasma status of antioxidant microconstituents and on the plasma total antioxidant capacity in healthy subjects. More research is needed to determine the effects of lycopene alone. Studies on lycopene supplementation for breast cancer prevention are lacking. It is possible that antioxidant vitamins may help to protect the macula against this deterioration and loss of vision. Conversely, there are studies that suggest caution with selenium supplement usage among males with prostate cancer.
Most importantly, further interventional studies are warranted to determine if lycopene supplementation could alter cardiovascular outcomes in at-risk populations. 34 In 997 middle-aged men, an inverse association was found between serum lycopene levels and overall cancer incidence. The evidence favors lycopene supplementation as a therapeutic strategy in lowering bp among hypertensive individuals (60, 129). Based on the results of 5 relevant studies with no substantial heterogeneity, lycopene showed no significant association with cataract risk. Early studies on breast cancer have looked for a possible link between disease risk and fruit or vegetable intake, tomato consumption, or lycopene levels, with mixed results. However, a post hoc exploratory analysis found lower psa values in men with intermediate-risk prostate cancer who consumed the tomato products and in men with the highest increases in lycopene levels. Table 2: Biological actions of lycopene in diseases s. Although generally regarded as safe, vitamin supplements may have harmful effects. Men who wish to supplement this nutrient may benefit more from a whole-food tomato concentrate than from isolated lycopene.
From a mechanistic standpoint, each aox assay provides somewhat different information relative to their action in the sense of antioxidants inhibiting formation of ros (Initiation) or impacting propagation and branching steps and thereby breaking radical chain sequences, and unfortunately, often yield incongruent results. Chronic ingestion of lycopene-rich tomato juice or lycopene supplements significantly increases plasma concentrations of lycopene and related tomato carotenoids in humans. However, among men with a family history of prostate cancer, increased lycopene consumption was associated with decreased prostate cancer risk. The duration of supplementation and follow-up ranged from six months to five years. Though antioxidant supplements are generally not recommended for a variety of reasons, the antioxidant vitamin c may benefit people with the common cold or those who smoke. In human serum,lycopene absorption influenced by lipids and lipid-soluble compounds and presence of carotenoids, vitamins, fibers, cooking temperature. Intestinal absorption of lycopene from different matrices and interactions to other carotenoids, the lipid status, and the antioxidant capacity of human plasma.
7 Processed tomato products are a better source of lycopene than fresh tomatoes, 8 with lycopene more bioavailable. Therefore, it is not possible to conclude whether there is an optimum duration of lycopene supplementation that would give the same results as those reported here without undertaking further study. Antioxidant supplements contain concentrated forms of antioxidants, which are substances that stabilize free radicals. Lycopene is a carotenoid and although there is no daily value for lycopene, dr. 15 In an 8-week, double-blind, randomized, placebo-controlled trial, lycopene supplementation decreased dna oxidative damage.