Product name: Now Foods, Pycnogenol, 30 mg, 60 Veg Capsules
Quantity: 60 Count, 0.05 kg, 5.1 x 5.1 x 10.4 cm
Categories: Now Foods, Supplements, Antioxidants, Pine Bark Extract, Pycnogenol, Vegetarian, Vegan, Non Gmo, Gmp Quality Assured, Produced In A Gmp Certified Facility
Free Radical Scavenger, With 300 mg Bioflavonoids, Healthy Vascular Function, Balanced Immune Response, Pycnogenol – Horphag Research, A Dietary Supplement, Vegetarian/Vegan, Non-GMO, General Health, Family Owned Since 1968, GMP -Quality Assured, Pycnogenol is a unique combination of proanthocyanidins obtained from the bark of the French maritime pine. As a potent natural scavenger of free radicals, Pycnogenol helps to protect the body’s tissues from oxidative stress and supports a healthy, balanced immune system response to normal metabolic stress. Through response to normal metabolic stress. Through these mechanisms, Pycnogenol helps to maintain healthy eye, skin, and joint tissues. In addition, scientific studies have shown that Pycnogenol helps to maintain vascular strength and function.
In contrast, serum concentration of vasoconstrictory mediators endothelin-1 and thromboxane are lowered in response to supplementation with pycnogenol. The extract has been widely studied for the past 40 years and has more than 280 published studies and review articles ensuring safety and efficacy as an ingredient. Stress, poor diet, and lack of sleep can all contribute to sub-optimal brain function, and while diet and exercise are fantastic for boosting healthy brain function, so too is pine bark extract. Should i take pycnogenol or regular pine bark extract? The low-dose buildup effect of pycnogenol as an antiinflammatory agent would make it useful in a multinutrient format, but it may not be the most potent antiinflammatory in isolation. Our objective was to determine the effects of pine bark extract on blood pressure and other cvd risk factors in overweight and obese adults with higher-than-optimal systolic blood pressure. Clinical studies using pine bark extracts report no clinically important adverse events at doses of 150 mg daily; however, few studies evaluate safety as a primary outcome. I am taking this in combination with life extension bilberry extract, and it is working well for me.
Now Foods, Pycnogenol, 30 mg, 60 Veg Capsules: Pycnogenol, Pine Bark Extract, Antioxidants, Supplements
Despite our extensive subgroup analysis, the only suggestion of an effect was for participants with baseline systolic blood pressure of 130 mm hg or higher, among whom the mean (Sd) lipoprotein(A) level decreased by 2 Nmol/l among 37 individuals in the pine bark extract group (Baseline level, 37 nmol/l) and increased by 4 Nmol/l among 38 individuals in the placebo group (47 Nmol/l). Derived from the bark of the french maritime pine tree. A study of 58 patients with hypertension showed that 100 mg of pycnogenol daily had a positive effect on their blood pressure. The water-soluble flavonoid extract was developed, trademarked, and patented by horphag research international. As someone who is been working in the supplement industry for a very long time, i cannot advise enough only working with brands and ingredients that are deeply invested in science and production. This bottle also contains 150mg of bioflavonoids per capsule added for their synergistic antioxidant properties. Pine bark extract can be taken either with or between meals. At six months, 87 percent of those who took pycnogenol were asymptomatic, compared to almost 35 percent of controls, and had significantly better blood flow in the cochlea (A part of the inner ear that plays a key role in hearing). Mcf-7 and mcf-10 cells were plated out in culture dishes and grown in medium containing 0, 40, or 80 micrograms pycnogenol/ml culture medium.
Stafford said the researchers felt these were the types of people who would be more likely to seek out dietary supplements as an alternative therapy. The participants were randomly assigned to take either a japanese-produced pine-bark extract or a placebo. In vitro and animal studies using the standardized extract have indicated a multimodal action of pycnogenol, and several human studies have shown improvements in cognitive function after chronic administration. Although the type of rampant inflammation during a flare far-exceeds the ability of pycnogenol, it has shown some efficacy for patients in remission phases of their disease, where symptoms tend to be driven by lower-level, chronic inflammation. Supplements containing the french maritime pine bark extract pycnogenol may help protect against the effects of oxidative stress after exercise, says a new study with 20 healthy young men. Pyc is a plant-based extract derived from the bark of the french maritime pine. To summarize, we found that caffeic acid, taxifolin, ferulic acid, and m1 all bind to human erythrocytes, but only the pycnogenol metabolite m1 revealed accumulation within the cells. In this study, we tested the antioxidant and anti-inflammatory effects of a supplement, hiper health supplement (Hiper), on cytokine-induced inflammation and oxidative stress in human coronary artery endothelial cells (Hcaecs).
Thanks to extensive research into the safety and efficacy of pycnogenol, we now know that there are many health benefits that our ancestors could only suspect through trial and error applications. Pycnogenol supplementation reduced skin redness from uv rays in a trial of 21 people over 8 weeks. Several studies 8, 12, 22 reported that pine bark extract decreases blood pressure. One study found that pycnogenol may reduce the activity of the inflammatory enzymes cox1 and cox2, similar to how nsaid drugs work. More research is needed to determine which individuals with hypertension may benefit from supplementation. Nutritional supplements are not as well-regulated, (Or minimally regulated) as prescription drugs. 3 This is why supplements derived from some of these plants have been shown to have similar effects as pycnogenol. Horphag research has done 40 years of research into the safety, quality, and efficacy of this wonder extract, making it one of the most studied ingredients in the world.
Pine bark extract 95%, opc is a term describing oligomeric proanthocyanidins, a natural substance derived from the bark of certain pine trees. Pycnogenol, rich of many phytochemicals of medical value, is a commercialized nutrient supplement extracted from the bark of european coastal pine. The story goes that first nations tribes shared their ancestral wisdom with cartier and used the local pine tree bark as a decoction (E. There is insufficient evidence to support the use of pycnogenol for any of the uses listed below. Doses of pine bark extract have been studied in clinical trials, most commonly at 150 mg per day in 3 divided doses. Pine bark extract contains proanthocyanidins (Same as does pycnogenol the trade marked name for pine bark extract) which are very powerful antioxidants – up to 50 times more potent than vitamin e and 20 times more than vitamin c. Athletes can also benefit from the increase in no supported by pine bark extract, through enhanced circulation and blood flow. A study of 147 people found that pycnogenol (100 Mg/day) may improve running, push-ups, and sit-ups endurance in recreational athletes over an 8-week training program. Regulations set manufacturing standards for supplements, but that does not guarantee that they are safe or effective. This supports the idea that taking pycnogenol may help control some cardiovascular risk factors, particularly in this patient population. In theory, pine bark may lower blood pressure and blood sugar level, and these effects have also been reported in some rcts.
Now Foods Pycnogenol
Pine bark extract is gras, based on data from animal studies and clinical trials; however, few studies evaluate safety as a primary outcome. Pine bark extract is able to cross the blood barrier of the brain to provide extra protection against free radicals in the nervous system and circulatory system. Citrus bioflavinoids and vitamin c are added for their synergistic antioxidant properties. I’ve been taking pine bark (Pycnogenol) since the 90S to help me manage my adhd and nothing is more powerful and helping me concentrate and alleviate many of the negative symptoms of adhd. Studies in spontaneously hypertensive rats suggest a protective effect on microvasculature by pine bark extract thought to be due to antioxidant effects. Pycnogenol is the trade name for an extract of french maritime pine bark (Pinus pinaster). Some people taking pycnogenol may experience bad breath, upset stomach, dizziness, sores in the mouth, or headaches.
Com and it’s editors do not ensure that unforeseen side effects will not occur even at the proper dosages, and thereby does not assume liability for any side effects from supplements or practices hosted under the domain of examine. Participants were asked to refrain from changing their diet, losing weight, and beginning new dietary supplements or medications during the study. The pine tree is native to the western and southwestern mediterranean regions but has rapidly naturalized to other countries, including the united states, england, south africa, and australia. Study results showed that 18 of the 24 participants who took pycnogenol had an improvement in their vision, while no such improvements were observed in those who took the placebo. The evidence supporting supplements made from french pine bark is not convincing. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. Conclusions this pine bark extract (At a dosage of 200 mg/d) was safe but was not associated with improvement in cardiovascular disease risk factors.
Pycnogenol may increase the risk of bleeding, so it should be avoided by those with bleeding disorders, people taking blood thinning medication or supplements, or in the weeks before surgery. Importantly, all studies found that pycnogenol has to be taken at least 5 weeks before the allergy season in order to see potential benefits, with the best results in those who take it 7-8 weeks ahead. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. The most important intracellular antioxidant in the human body is glutathione (Gsh). Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. 9, 11, 12 Pine bark extract has been reported to reduce blood concentrations of endothelin, an endothelial-derived vasoconstrictor. There is additional evidence to support that pycnogenol may be helpful in other ways for people with diabetes. 16 Cardiomyopathy in diabetic rats was reduced by pine bark extract, also considered to be due to antioxidant activity, but possibly due to improved cardiac energy metabolism via observed lowered plasma glucose. Pycnogenol (Pic-noj-en-all) is an extract of french maritime pine bark (Pinus pinaster) that contains powerful nutrients called procyanidins (A group of bioflavonoids, also found in some fruit). It is included in hundreds of dietary supplements, cosmetic products and functional foods and beverages worldwide.
Remember to speak with a doctor before taking pycnogenol. The aim of this study is to investigate anticancer effect of pycnogenol in mc-3 human mucoepidermoid carcinoma (Mec) cell line. Pine bark extract is rich in plant pigments called bioflavonoids. A number of natural antioxidant ingredients also have anti-inflammatory properties, and can be used in the treatment of oxidative damage such as photoaging and perhaps even skin cancer. This may account for variations in physiologic effects among different pine bark extract preparations and among antioxidants in general. Our pure, non-gmo pycnogenol capsules feature the well-studied french maritime pine bark extract, sourced exclusively from les landes de gascogne forest which is free of pesticides and herbicides. Is available in more than 1,000 dietary supplements, multi-vitamins and health products worldwide. In addition, although there were no previous safety concerns about pine bark extract, this study contributes to evidence about the safety of pine bark extract, including it’s effect on liver function. Hiper health supplement (Hiper) was formulated using a combination of french maritime pine bark extract (Pinus pinaster, pbe), aloe vera, honey, and papain.
Of 130 randomized participants, 7 participants (4 In the pine bark extract group and 3 in the placebo group) dropped out before the 6-week data collection point, and 2 participants in the placebo group dropped out after the 6-week data collection point, for a 93,1% retention rate (Figure 1). Pine bark extract is available through other companies not using pycnogenol, except that they may use different types of pine bark and have dissimilar formulations. In a study of 61 adhd children, pycnogenol reduced hyperactivity, improved attention, and motorics after 1 month.