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But how, exactly, does fish oil benefit the adhd brain? Important eicosanoids produced from epa are prostaglandins of the 3 series (Prostaglandin e 3) and leukotrienes of the 5 series (Leukotriene b 5). E, polyunsaturated fatty acids, minor compounds as volatiles, and antioxidant molecules). Although it is not clear if these findings translate to impaired immune responses in vivo, caution should be observed when considering omega-3 fatty acid supplementation in individuals with compromised immune systems. The american heart association recommends at least two servings of oily fish per week, but omega-3 fatty acids are often in short supply in our diets. Aa, which generally comprises more than 20% of the total fatty acids in cell membrane phospholipids in the skin, is converted to prostaglandins of the 2 series (Prostaglandin e 2) and leukotrienes of the 4 series (Leukotriene b 4). The absence of methylmercury in omega-3 fatty acid supplements can be explained by the fact that mercury accumulates in the muscle, rather than the fat of fish.