Product name: Solgar, No-Flush Niacin, 500 mg, 250 Vegetable Capsules
Quantity: 250 Count, 0.41 kg, 7.4 x 7.4 x 13.7 cm
Categories: Solgar, Supplements, Vitamins, Vitamin B, B3 Niacin, Dairy Free, Casein Free, Vegetarian, Kosher Parve
Since 1947, (Inositol Hexanicotinate), Cardiovascular Support, Supports Energy Metabolism, Gluten, Wheat and Dairy Free, Suitable for Vegetarians, Kosher Parve, Dietary Supplement, Niacin/ Vitamin B3, is a water-soluble vitamin and is part of the B Complex. It is required for the metabolism of carbohydrates and protein into energy. Niacin supports cardiovascular health. The unique, inositol-bound niacin in this formula allows for a gentle, no-flush delivery of niacin to the body.
Mild niacin deficiency can be caused by digestive problems that decreases the amount of vitamin b 3 (Niacin) or tryptophan that your body absorbs. I then read that flush niacin would be more effective. I am not a doctor and am only providing my experience with this supplement. Some people use niacin or niacinamide for acne, leprosy, attention deficit-hyperactivity disorder (Adhd), memory loss, arthritis, preventing premenstrual headache, improving digestion, protecting against toxins and pollutants, reducing the effects of aging, lowering blood pressure, improving circulation, promoting relaxation, improving orgasm, and preventing cataracts. A: Niaspan (Extended release niacin) is a prescription medication that can be used to reduce triglycerides (A fat-like substance) and cholesterol levels in the body. Because of possible side effects, anyone taking such high amounts of niacin and vitamin b6 must do so only under the care of a doctor. Some niacin products are fda-approved prescription products for treating high cholesterol. Studies show that the benefits to lowering bad cholesterol with the ih form of niacin are not nearly as effective as free-from niacin. Effects of niacin on the incidence of new onset diabetes and cardiovascular events in patients with normoglycaemia and impaired fasting glucose.
Solgar, No-Flush Niacin, 500 mg, 250 Vegetable Capsules: B3 Niacin, Vitamin B, Vitamins, Supplements
On this basis, those who eat a well-balanced diet will tend to consume enough niacin in their food. New developments in the use of niacin for treatment of hyperlipidemia: New considerations in the use of an old drug. Current uk guidelines advise everyone to consider taking a vitamin d supplement during winter. In particular, the activation of parp enzymes (Artds) by oxidative damage to dna could be responsible for inducing niacin/nad depletion (See function). Skin texture and skin barrier function may benefit from consistent ceramide supplementation. The niacin form of vitamin b3 has been reported to be effective in relieving menstrual cramps in 87% of a group of women taking 200 mg of niacin per day throughout the menstrual cycle. Older people taking 3 mg of vitamin b2 and 40 mg of vitamin b3 per day were partly protected against cataracts in one trial. It is also important to monitor your b vitamin intake if you follow a diet that does not include meat or fish as some b vitamins, such as b12, are found predominantly in meat and fish. Nicotine patch (Transdermal nicotine) niacin can sometimes cause flushing and dizziness.
Several thousand tons of niacin are manufactured each year, starting from 3-methylpyridine. Low-dose aspirin and ibuprofen reduce the cutaneous reactions following niacin administration. My b vitamins smell and make my urine smell bad. There are potential side-effects of niacin therapy, including an uncomfortable flushing sensation, dermatitis (Skin inflammation), heartburn, aggravation of peptic ulcers, increased blood sugar, increased panic and anxiety, and elevation of liver enzymes, which may indicate damage to liver cells. So you need niacin to produce nadh to transfer the energy from the food you eat into a type of energy your body can use. Varying cost and free nicotinic acid content in over-the-counter niacin preparations for dyslipidemia. In a preliminary trial, some schizophrenic patients continued a course of vitamins (4 To 10 grams of niacin or niacinamide, 4 grams of vitamin c, and 50 mg or more of vitamin b6) after being discharged from the hospital, while another group of patients discontinued the vitamins upon discharge. Finally, other populations at risk for niacin deficiency include dialysis patients, cancer patients (36, 37), Individuals suffering from chronic alcoholism, And people with hiv (See hiv/aids below). And you get niacin from eating certain foods including beef, chicken, tuna, sunflower seeds, salmon, green peas, turkey, and mushrooms.
Cleary concluded that alcoholism might be a manifestation of niacin deficiency in some people and recommended that alcoholics consider supplementation with 500 mg of niacin per day. Niacin is referred to as vitamin b 3 because it was the third of the b vitamins to be discovered. But when adding niacin to their supplement stack, most experience a reduction in blood pressure. Severe reversible hyperglycemia as a consequence of niacin therapy. Tolerable upper intake levels for vitamins and minerals (Pdf). What we like: A highly reputable manufacturer that makes supplements for those with multiple sensitivities. Since other actions of niacin lower heart disease risk, the importance of this finding is unclear. For that reason, if you have diabetes, you should take niacin only under the direction of your doctor, and you should be carefully monitored for high blood sugar. Inositol hexaniacinate: A safer alternative to niacin.
For more specific information regarding extended-release niacin dosage and appropriate titration to a therapeutic level, speak with your physician. At high doses, niacin might help people with heart disease because of it’s beneficial effects on clotting. The authors attribute this protection to niacin’s anti-inflammatory and anti-angiogenic effects. Niacin is used to treat or prevent a deficiency of the vitamin. The b vitamins are a family of water-soluable nutrients that play an important role in almost every biochemical process that occurs in the body. Many doctors advise against self-medicating with niacin and suggest that in many cases supplementation is not needed. When taken as a supplement, niacin is often found in combination with other b vitamins. While one study noted an increase in blood flow in subjects on medication who were given additional niacin, other studies do not find an interaction with niacin and blood flow. People with diabetes who take niacin should check their blood sugar carefully. Large doses of niacin may cause increased blood sugar levels, liver damage, peptic ulcers, and skin rashes. One study reported that niacin supplementation decreased the risk of ultraviolet light (Uv)-induced skin cancers in mice, despite the fact that mice convert tryptophan to nad more efficiently than rats and humans and thus do not get severely deficient. But only about 2% of dietary tryptophan is converted to niacin.
Solgar B3 Niacin
Niacin might have an additive effect when you take blood pressure drugs, herbs or supplements. High levels of niacin are also included in our b50 complex and b100 complex. It is important to talk with your physician regarding taking niacin. A phase iii, randomized, double-blind, placebo-controlled trial in 386 subjects with a history of nonmelanoma skin cancer recently examined the effect of daily nicotinamide supplementation (1 G) for 12 months on skin cancer recurrence at three-month intervals over an 18-month period. I highly recommend taking it on evenings when at home otherwise if taking niacin in the morning you might have to explain everyone at the office why you look like a cooked lobster! Niacin, also called nicotinic acid, is a b vitamin (Vitamin b3) used in vitamin supplements and in combination with prescription drugs. There is also some concern that consuming alcohol with niacin might increase the chance of having liver damage. The mainstay of the orthomolecular approach to schizophrenia is niacin or niacinamide (Vitamin b3) in high amounts.
The therapeutic effects of niacin are partly mediated through the activation of g protein-coupled receptors, including niacin receptor 1 (Niacr1) and niacin receptor 2 (Niacr2) which are highly expressed in adipose tissue, spleen, immune cells, and keratinocytes, but not in other expected organs such as liver, kidney, heart or intestine. A pooled analysis of two large us prospective cohort studies that followed 41,808 men and 72,308 women for up to 26 years suggested that higher versus lower intake of niacin (From diet and supplements) might be protective against squamous-cell carcinoma but not against basal-cell carcinoma and melanoma. High doses of niacinamide may damage the liver or kidneys and make liver disease or kidney disease worse. Some doctors recommend inositol hexaniacinate (A special form of vitamin b3) as an alternative to niacin. This lack of niacin may also be observed in pandemic deficiency diseases, which are caused by a lack of five crucial vitamins (Niacin, vitamin c, thiamin, vitamin d, and vitamin a) and are usually found in areas of widespread poverty and malnutrition. Overall, the addition of nicotinic acid supplementation (Dose range not specified) to statin therapy taken for a mean of 33 months (With a broad range of 6 to 60 months) did not lead to significant reductions in rates of all-cause or cardiovascular mortality, myocardial infarction, or stroke. In a preliminary trial, 60 mg per day of vitamin b6 resulted in symptomatic improvement in only 5% of schizophrenic patients after four weeks.
Directions: As a dietary supplement, take 250 mg to 500 mg (3/16 Tsp) daily with meals, or as directed by a physician. And when combined with niacin it may increase this muscle wasting problem. Niacin rdas for adults are based on niacin metabolite excretion data. The recommended dose of niacin varies according to the type of capsules or tablets you are using, and the condition being treated. Furthermore, even much lower doses of niacin than the usual dose given to improve cholesterol levels (100 Mg versus 1,000 mg or more) may provide a similar benefit. Medications that can harm the liver (Hepatotoxic drugs) niacin might harm the liver. Comes in two principal forms: Niacin (Nicotinic acid) and niacinamide (Nicotinamide). Vitamin b3 foods which foods are the best sources of niacin? Side effects associated with niacinamide include upset stomach, excessive gas, dizziness, and mouth pain. For this reason, people who consume corn as tortillas or hominy are not at risk of niacin deficiency. Because pellagra represents severe deficiency, the food and nutrition board (Fnb) of the us institute of medicine chose to use the excretion of niacin metabolites as an indicator of niacin nutritional status rather than symptoms of pellagra. This might reduce the effectiveness of niacin.
As a supplement, niacin may help lower cholesterol, ease arthritis and boost brain function, among other benefits. Megavitamin b-3 therapy for schizophrenia. However, the low doses of aspirin most commonly used for niacin-related flushing do not seem to be a problem. Therefore, if tolerable, ir niacin might be a good and cost-effective choice, especially if you use the prescription version or a reliable non-prescription version. For more information on niacin, visit // for more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.