Product name: Solgar, Quercetin Complex with Ester-C Plus, 50 Vegetable Capsules
Quantity: 50 Count, 0.16 kg, 5.3 x 5.3 x 9.7 cm
Categories: Solgar, Supplements, Antioxidants, Quercetin, Dairy Free, Casein Free, Vegan, Kosher Parve
Since 1947, Unique Synergistic Formula, Immune Health Support, Gluten, Wheat and Dairy Free, Suitable for Vegans, Kosher Parve, Dietary Supplement, Solgar’s Quercetin Complex includes the important bioflavonoid Quercetin in a synergistic formula with Ester-C Plus and Bromelain to provide unique antioxidant protection as well as natural seasonal support. Quercetin is found in onions and other foods. It possesses antioxidant properties which help to stabilize cell membranes. Ester-C Plus provides a patented, pH neutral (non-acidic), form of vitamin C that is gentle on the stomach. Ester-C Plus offers the additional benefits of incorporating acerola berry, citrus bioflavonoids, rutin and rose hips. This formula also features bromelain, a natural enzyme derived from pineapple.
Especially the ability of quercetin to scavenge highly reactive species such as peroxynitrite and the hydroxyl radical is suggested to be involved in these possible beneficial health effects. Patients taking these supplements should talk to with their provider about whether or not to stay on the supplement during treatment. Well-known antioxidants and newcomers in sport nutrition: Coenzyme q10, quercetin, resveratrol, pterostilbene, pycnogenol and astaxanthin. In fact, the antioxidant capability of flavonoids found in laboratory studies may be irrelevant because it’s yet to be determined how well they are absorbed by the body. 8 Only a few studies have provided detailed information on adverse effects of quercetin supplements, especially for long-term treatment (More than 12 weeks) with high doses (1,000 Mg/day or more). The antioxidant capacity, determined by a ferric reducing ability of plasma (Frap) assay, has been shown to vary between apple genotype, and has been demonstrated to relate directly to the polyphenol content of the fruit. The vast majority of the studies conducted on quercetin were done with cell cultures and animals. The enhanced absorption of quercetin resulting from combining it with green tea may work 2 ways. Many people take antioxidants during treatment with the view that they can protect normal tissues from treatment side effects.
Solgar, Quercetin Complex with Ester-C Plus, 50 Vegetable Capsules: Quercetin, Antioxidants, Supplements
Quercetin is gaining popularity as a supplement for supporting the healthy inflammatory response and supporting athletic endurance and performance products, but what exactly is it? My husband and i both use this along with bromelain 500 mg as support for seasonal allergies (Sinus), antioxidant support along with anti-inflammatory properties for muscle pain. The patients were administered with curcumin 480 mg and quercetin 20 mg orally 3 times a day for mean of 6 months. It has also been reported in rat that higher concentrations of quercetin cause nerve cell damage with equal chances of apoptosis and necrosis. Impact of sirtuin-1 expression on h3k56 acetylation and oxidative stress: A double-blind randomized controlled trial with resveratrol supplementation. When asked to list your medications, include all vitamins, supplements, and over the counter medications. Vitamins c and e supplementation had no significant effect on any of the studied parameters. For example, many in vitro experiments use concentrations of antioxidants that are much higher (Sometimes orders of magnitude greater) than those that are likely to be found in vivo after oral ingestion. Both fish oil and omega-3 fatty acid supplements may lower the ability of your platelets to work, which can cause bleeding.
This chapter focuses on experimental studies supporting the anticancer, cardioprotective, and neuroprotective effects of quercetin. Within this time span, 45 days were dedicated to examining the effects of the intake of a beverage rich in polyphenols (One serving: 200 Ml per day) supplemented in their diet. In the present report, we show that quercetin inhibits frtl-5 cell growth and inhibits function by apparently specifically down-regulating the expression of nis gene and function. Each liquid supplement contained green tea (300Mg), vitamin c (150Mg), vitamin e (50Mg), caffeine (45Mg), niacin (25Mg), taurine (9Mg), vitamin b6 (2,5Mg) vitamin b2 (2,1Mg), vitamin b1 (1,9Mg), and vitamin b12 (0,008Mg). Generally, the term quercetin should be used to describe the aglycone only; however, the name is occasionally used to refer to quercetin-type molecules, including it’s glycosides in research and the supplement industry. Analytical techniques for the identification of quercetin have been described. The supplement should also provide information on the enzyme activity such as 2,400 gdus per gram. Synergy between ethanol and grape polyphenols, quercetin, and resveratrol, in the inhibition of the inducible nitric oxide synthase pathway. Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. The beneficial effects of flavonoids like quercetin come from their ability to function as antioxidants inside your body. Pregnant women, breastfeeding women, and people with kidney disease should avoid quercetin.
Towards an understanding of the low bioavailability of quercetin: A study of it’s interaction with intestinal lipids. Flavonoids include flavonols (Quercetin), flavones (Luteolin), flavanones (Naringenin), anthocyanidins (Cyanidin) and isoflavones (Genistein). We focus on the most recent studies, predominantly performed in humans, reporting a definite, beneficial effect of the natural antioxidant intake associated with regular physical activity for adulthood and elderly subjects. Most research has focused on the antioxidant properties of quercetin, it’s effects on several enzyme systems, and effects on biological pathways involved in carcinogenesis, inflammation and cardiovascular diseases. The effect of antioxidant supplements on all-cause mortality was analyzed with random-effects meta-analyses and reported as relative risk (Rr) with 95% confidence intervals (Cis). 44, 46, 47 Rutin has been shown to decrease the anticoagulant effect of warfarin, and limited studies suggest quercetin similarly exhibits antiplatelet aggregation activity. The outermost layers of onions and dried, not fresh, shallots are rich in quercetin. B, inhibition of tritiated thymidine incorporation into dna by quercetin.
Summary quercetin may improve inflammation, blood pressure, exercise performance, and blood sugar control. Another found that frequent intake of quercetin-rich foods was associated with lower lung cancer risk. According to the results obtained both in vitro and in vivo, good perspectives have been opened for quercetin. Most people have heard of flavonoids, plant-based antioxidant pigments that are being touted for many alleged health benefits. Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress. Using frtl-5 cells as an in vitro model of thyroid cells, which retain all the properties of normal thyroid cells, we observed that quercetin inhibits cell growth and specifically appears to decrease the rna levels of nis gene by different mechanisms, despite it’s ability to inhibit both activities at in a similar concentration-dependent manner. Effect of resveratrol and quercetin supplementation on redox status and inflammation after exercise. You should always check with your healthcare provider before taking any supplement. Quickly and easy look up evidence on over 400 supplements across over 500 different health goals, outcomes, conditions, and more. There are not enough clinical data to rate the effectiveness of quercetin for ulcers.
To protect against exercise-induced oxidative injury, muscle cells contain complex endogenous cellular defence mechanisms (Enzymatic and non-enzymatic antioxidants) to eliminate reactive oxygen species. It also showed quercetin could protect against the toxic effect of certain metals on the nervous system. The search leading to compound with antioxidant activity has increased in the last few decades. Health effects of quercetin: From antioxidant to nutraceutical. In conclusion, these data suggest that an antioxidant supplementation with natural compounds, accompanied by a constant physical exercise session, represents a useful mean to reduce oxidative stress and to alleviate the age-related pathophysiological disorders. Antioxidants are widely used as supplements but whether they affect the health-promoting effects of exercise is unknown. This chemical diversity impacts heavily on bioavailability, metabolism, and cellular distribution of any given antioxidant; lipophilicity will predispose to accumulation in cell membranes and circulating lipoproteins, while water-soluble agents are unlikely to penetrate cell membranes without the aid of transporters. Many people being treated for cancer with radiation take supplements.
Besides the endogenous enzymatic and non-enzymatic antioxidant defenses that the human body develops to cope with the excess of free radicals produced upon oxidative stress, and besides the protective mechanisms of scavenging or detoxifying ros, blocking ros production or sequestering transition metals, the body exploits also other antioxidants which are normally supplied within the diet and which are called exogenous antioxidants (Figure 1). Analysis showed that 30km time trial time was improved by 3,1% in the group taking the combined supplement with quercetin with a 2% improvement in time over the last 5km. Both bromelain and quercetin supplements are relatively easy to find, but these products are typically sold in combination with other enzymes (E. There were no changes in concentration of 1,25(Oh)2d3 and markers of antioxidant status associated with vitamin d or quercetin supplementation. Frtl-5 cell growth inhibition by quercetin. A limitation of this study is that the study group (Us physicians) is highly educated and likely to be well-nourished, with a balanced diet; vitamin supplements might be superfluous in such a group. As such, it is an attractive target for antioxidant therapy, but the success or otherwise of proposed interventions will rely on the ability to deliver sufficient amounts of the appropriate antioxidant to the right target, which is not a trivial issue to resolve.
Studied the effect of quercetin (20 Mg) and curcumin (480 Mg) on fap in five patients and found to be effective against fap. In the majority of the literature, we find references to the benefits of prolonged supplementation with quercetin. Free radicals and antioxidants in normal physiological functions and human disease. Plasma quercetin response to 12 weeks quercetin supplementation: A randomized community clinical trial. While studies have shown that populations with high intakes of flavonoids in general have lower risk of several diseases related to inflammation,9-11 quercetin does not exist in foods alone, making it almost impossible to separate it’s effects from other flavonoids. Remember to speak with a doctor before taking quercetin supplements. Quercetin, a plant pigment is a potent antioxidant flavonoid and more specifically a flavonol, found mostly in onions, grapes, berries, cherries, broccoli, and citrus fruits. For quercetin, dosing is measured in milligrams (Mg). In rats, post-trauma administration of quercetin improves recovery of motor function after acute traumatic spinal cord injury.
Polyphenols stimulate the body to defend against free radicals, so getting lots and lots of plant polyphenol antioxidants is important. In vitro and animal studies have attempted to elucidate possible mechanisms of action for quercetin in cancer. Every batch of the quercetin supplement is independently tested prior to packaging for authenticity, potency, heavy metals, solvent residue, herbicide and pesticide residue, aflatoxins, stability, and bacteria to guarantee the highest quality supplements with each purchase. However, most human studies have looked at flavonoids in the diet, not as supplements. In summary, our data show that quercetin inhibits thyroid growth, acting, at least in part, by inhibiting pi3k/akt activity. 4 It would take approximately 100 g (3,5 Oz) of fresh red onion to be comparable to 500 mg of quercetin supplements in tablet form. Isoquercetin (Glycosylated quercetin) is more completely absorbed than the quercetin aglycone form, most probably because the carbohydrates linked to the flavonoid (Glycone) exert an important vehiculation role in the absorption due to the more hydrophilicity of the glicoside.
At oral supplemental doses of up to 1,000 mg per day taken for up to 12 weeks, no evidence of toxicity has been found; however, data on long-term safety at high doses are lacking. Then 17 men also received bromelain and papain as an add-on to enhance quercetin absorption, along with palmetto and cranberry.
Solgar, Quercetin Complex with Ester-C Plus, 50 Vegetable Capsules Product Review
OK. For pockets and allergies. best. great for allergies. For immunity, yes! will reorder. Ok. Allergy works. Expensive but effective
Excellent for treating seasonal allergies and nasal sinuses much better than bad antihistamines
best vitamin c
Love this product really helps with my allergies.
This drug was taken to strengthen the immune system after a serious inflammation of the lymph node. After antibiotic treatment! I began to drink this complex, because it was very weak. She quickly returned to her usual rhythm. But I read a lot that helps with allergies. I did not help with food allergies. Although I have been taking it a lot (more than a month). maybe I should drink longer from allergies or increase the dose?
very good will reorder
I am a teacher and work with children from 6 to 11. In the seasons of ARVI and influenza, very often, 10-15 times, got colds, often sore throat. Since our working body is the vocal cords, loaded for 5-6 hours daily, it hoarsed and sometimes lost its voice. With this quercetin and from Now food I worked without colds! There were mild symptoms that disappeared in a day or two. Saw from October to April, 1-2 capsules per day. Definitely buy and drink! God forbid we do not get sick!
I ordered my husband (he is allergic to dust, his nose and cough are constantly stuffed up). After 1 week of taking 1 tablet in the morning and evening, the symptoms of allergies decreased significantly, and then completely disappeared! Definitely recommend it! And I’ll take it myself.
I’m looking forward
Questions and Answers
Hi guys, does this product contain any GMO ingredients or residues? Thank you kindly.
Hi, I would like to know what source is the Quercetin made from? Thanks.
Does this product contain any GMO’s? Thanks.
Does this interact with Antibiotics like Augmenting?
Hi, when it comes to this medication?
Would you explain what does the daily dose depends on? In various instructions there are different recommendations of daily doze. Which one is correct?
Quote taken from the Solgar desk reference manual. Since high quality nutritional supplements shouldn’t cause allergic reactions, we strive to eliminate as many allergens from our formulas as possible. Almost all Solgar products are free from sugar, salt, starch, yeast, corn, soy, wheat, gluten and dairy products and contain no preservatives, artificial flavours or colours.
Quercetin is an antioxidant that belongs to a class of water-soluble plant substances called flavonoids, which are present in certain fruits and vegetables. Quercetin is also available in supplement form, as pills or capsules. Sometimes, quercetin is packaged with bromelain, an enzyme found in pineapples, because both are said to have anti-inflammatory properties. Other forms of quercetin include hesperidin-methyl-chalcone (HMC) or quercetin chalcone.1
It does not contain GMOs. Anti allergic. You can get it with peace of mind. I advise. I have been using it for 2 years.
I’ve been on several antibiotics over the last couple of years while taking this and not had any interactions from it. I find it to be a great product and several herbalist/naturopath friends really like it too. I have taken it while breastfeeding as well.
Quercetin is a good antioxidant.
The daily dose is usually determined by doctor’s advice. For example, the dose we used for our 8-year-old child was determined to be 1 per day with the doctor’s advice.