Source Naturals, Vitamin D-3, 10,000 IU, 120 Softgels

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Product name: Source Naturals, Vitamin D-3, 10,000 IU, 120 Softgels
Quantity: 120 Count, 0.05 kg, 7.6 x 4.3 x 4.3 cm
Categories: Source Naturals, Supplements, Vitamins, Vitamin D, D3 Cholecalciferol

Dietary Supplement, For Bone and Immune Health, Sunlight is the source of life on Earth, but we may not be away of all the ways it benefits us. Our bodies manufacture vitamin D-3 when the skin is exposed to UV radiation from sunlight, but the ability to do so decreases as we age. Vitamin D-3 helps maintain healthy calcium and phosphorus levels in the body for strong bones, it supports muscle strength in older adults and it also plays an active role in a healthy immune response. Vitamin D-3 (cholecalciferol) is the optimal form of vitamin D. It is the form of vitamin D that the body manufactures in sunlight, and the form most efficient for the body’s needs.

The cure came not from sunshine itself, but from vitamin d, an essential chemical that the body makes in the presence of uv light. The role of vitamin d in reducing cancer risk and progression. When the active form of vitamin d binds to this receptor, it turns genes on or off, leading to changes in your cells. In fortified foods and supplements, vitamin d is also available in two forms, vitamins d2 (Ergocalciferol) and d3 (Cholecalciferol), that differ in their side-chain structure only. Animal studies and a limited number of observations from human cases offer insight into alterations in vitamin d metabolism during states of intoxication (37, 38, 41, 42). Summary evidence suggests that vitamin d works with magnesium and vitamins a and k to promote health. Vitamin d3 may be more than three times as effective in raising concentrations of vitamin d in the bloodstream and maintaining those levels for a longer time. Therefore, health providers should encourage patients to regularly exercise, maintain a healthy weight, eat healthfully, and take daily supplements, dr. Additional vitamins: Some d3 supplements include vitamin k, which is believed to work with d to help regulate calcium (Vitamin d helps your body absorb calcium). Doctor said the wife was very low on vitamin d and suggested vitamin d pills but we went for this instead. To see the full set of research information and references for vitamin d. Although tentative data link low levels of vitamin d to asthma, evidence to support a beneficial effect on asthmatics from supplementation is inconclusive.

Source Naturals, Vitamin D-3, 10,000 IU, 120 Softgels: D3 Cholecalciferol, Vitamin D, Vitamins, Supplements

One microgram of vitamin d is equal to 40 iu. Governmental regulatory agencies stipulate for the food and dietary supplement industries certain health claims as allowable as statements on packaging. The current article is part of the vitamin d and oral health project at the school of dentistry at the university of rwanda college of medicine and health sciences through rwanda human resources for health program in collaboration with harvard university. Future considerations not addressed specifically by studies in this review include: Vitamin d doses to prevent the winter decline of serum 25(Oh)d; Vitamin d supplementation in healthy, nonelderly adult populations; and The duration of the serum 25(Oh)d increase following supplementation. People with granulomatous disorders and some lymphomas may be more likely to develop hypercalcemia and hyperphosphatemia when serum 25(Oh)d levels rise above 30 ng/ml; supplementation with 400 iu d3 daily may be adequate to maintain vitamin d status and avoid adverse effects in this population. Tibial bone responses to 6-month calcium and vitamin d supplementation in young male jockeys: A randomised controlled trial. Rickets has been mostly eliminated from western countries because of the fortification of some foods with vitamin d.

To evaluate the effect of intervention on serum 25-hydroxyvitamin d levels, trials had to report serum levels at some point during the trial for the control and the intervention groups separately. Therefore, for consistency, trials were stratified by baseline vitamin d sufficiency for observing vitamin d3 supplementation effects on serum 25(Oh)d. British doctor edward mellanby noticed dogs that were fed cod liver oil did not develop rickets and concluded vitamin a, or a closely associated factor, could prevent the disease. The evidence for other health effects of vitamin d supplementation in the general population is inconsistent. The benefits of vitamin d supplementation are restricted to a small group of patients, but the use of vitamin d is often extrapolated inappropriately to a much larger group of patients. The latest research, however, shows that 1,25-dihyroxy vitamin d3 deficiency is linked to a surprising number of other health conditions such as depression, back pain, cancer, both insulin resistance and pre-eclampsia during pregnancy, impaired immunity and macular degeneration. Of note, most dosing is in terms of international units, or iu (1 Iu is the equivalent of 25 ng of vitamin d).

Stability of vitamin d in foodstuffs during cooking. Vitamin d supplementation for women during pregnancy. Low serum vitamin d levels and tuberculosis: A systematic review and meta-analysis. Recent studies show that people who are overweight may have higher levels of vitamin d. Does it matter when you take the vitamin d i. Had severe vitamin d deficiency which caused my calcium levels to decline – this gave me back pain, restless legs, knee pain, weakness and depression. Maternal vitamin d deficiency may cause overt bone disease from before birth and impairment of bone quality after birth. Produced in response to sunlight hitting your skin, vitamin d helps keep your immune system in top shape. He called it vitamin d because it was the fourth vitamin to be named. Influence of vitamin d mushroom powder supplementation on exercise-induced muscle damage in vitamin d insufficient high school athletes. Many animals synthesize vitamin d 3 from 7-dehydrocholesterol, and many fungi synthesize vitamin d 2 from ergosterol. The best way to tell if you need to supplement with vitamin d is to get a blood test from your doctor. Prevalence of vitamin d inadequacy in athletes: A systematic-review and meta-analysis.

Assessment of vitamin d concentration in non-supplemented professional athletes and healthy adults during the winter months in the uk: Implications for skeletal muscle function. Also, for your skin to synthesize vitamin d, you need to be exposed to uvb radiation. Although this syndrome is rare, it exemplifies the role of genotype on vitamin d metabolism and response to supplementation. Vitamin d supplementation, moderate sun exposure, and control of immune diseases. Cholecalciferol supplementation alters gut function and improves digestibility in an underground inhabitant, the naked mole rat (Heterocephalus glaber), when fed on a carrot diet. If you are active and healthy, you are unlikely to benefit from testing, you can just take a supplement as recommended. Foodpharmacy Blog and it’s editors do not advocate nutritional supplementation over proper medical advice or treatment and this sentiment will never be expressed through pages hosted under examine. Unlike cholecalciferol, which is typically only available as a maximum dose of 5,000 units per capsule or tablet, ergocalciferol is available as a monster 50,000 unit dose. The amount of sunlight needed to synthesize adequate amounts of vitamin d varies, depending upon the person’s age, skin color, sun exposure, and underlying medical problems. Finally, vitamin d deficiency is linked to a reduced life expectancy (27, 28, 29).

Source Naturals D3 Cholecalciferol

55, 78- 81 Although most osteoporosis treatment and prevention research has been centered around increased calcium and vitamin d intake, a study 82 has shown that persons who consumed the highest amount of magnesium (420 Mg for males and 320 mg for females) had higher bone density and lower risk of osteoporosis (Figure 3). I do wish you would consider doing some writing about vitamin b12 and the need for testing individuals that have lost the ability to fully utilize or uptake b12 from foods rich in b12, we have about seven members (Age 66 to 87) in our diabetes support group that need to take a vitamin b12 supplement on a daily basis. An optimal therapeutic dose of vitamin d must balance these potential negative impacts on bone mineralization. We made a second search in the reference lists of five recent systematic reviews of randomized trials with oral intake or i am injection of vitamin d supplements in caucasian 50-yr-old subjects. Evaluation, treatment, and prevention of vitamin d deficiency: An endocrine society clinical practice guideline. More recently, a number of trials in healthy children tested vitamin d doses at the upper levels set by the iom and with the goal of increasing serum concentrations above 30 ng/ml. Serum calcium concentrations plotted against 25ohd concentrations (Left) and vitamin d intake (Right) in infants and children with vitamin d intoxication.

We suggest vitamin d3 when possible, rather than vitamin d2, because vitamin d3 is the naturally occurring form of the vitamin and it may raise vitamin d levels more effectively. Oily fish like salmon, codfish, mackerel, and blue fish are great natural sources of vitamin d. 88 Studies have suggested that magnesium could influence pth synthesis and determine the number of vitamin d receptors; therefore, a deficiency in magnesium levels may lead to diminished synthesis and secretion of pth and a reduced number of available vitamin d receptors in the target cells. Additional studies are needed to determine the potential fracture risk posed by high-dose vitamin d, particularly in patients at risk for fractures and osteoporotic changes. Consuming the rda of magnesium may be more effective in preventing bone thinning than vitamin d, as magnesium potentiates vitamin d activities, possibly by increasing it’s absorption and endogenous activation. The skin uses the energy of uvb to convert 7-dehydrocholesterol into vitamin d3, even individuals, who venture out into the sun often and use suntan lotion, may be deficient in vitamin d3, furthermore, as we age, we are less equipped to produce sufficient quantities of this vital nutrient. I also discuss a reduction in vitamin d supplementation if a patient has a blood level greater than 50 ng/ml. In the epidermal strata of the skin, vitamin d production is greatest in the stratum basale (Colored red in the illustration) and stratum spinosum (Colored light brown).

Abundant sunshine and vitamin d deficiency. As vitamin d can be synthesized in adequate amounts by most mammals exposed to sufficient sunlight, it is not an essential dietary factor, although not technically a vitamin. This systematic review demonstrated the consistent efficacy and safety of single, large, oral doses of vitamin d in adults. Geographical location: People who live in northern latitudes or areas of high pollution, work night shifts, or are homebound should aim to consume vitamin d from food sources whenever possible. Extra vitamin d offered no heart protection (Sn: 12/8/18, P. Inexpensive vitamin d could potentially slash 30 percent of the income from the billion dollar cancer and cardiac industries alone. Similarly, in adults, vitamin d deficiency manifests as osteomalacia, or softening of the bones. Vitamin d supplements were sometimes administered as weekly or monthly doses, principally in trials that used vitamin d2 in subjects over 79 yr old. The effects of season-long vitamin d supplementation on collegiate swimmers and divers.

We first performed graphical exploration of data and then an investigation of variability of changes in 25-hydroxyvitamin d levels due to doses, type of vitamin d, calcium supplementation, 25-hydroxyvitamin d baseline values, gender, mean age, type of population, length of follow-up, country, and publication year through meta-analytic methods. Studies show that vitamin d may ease symptoms in people with clinical depression. Concomitant use of calcium supplements in the whi trial may have contributed to reduced adherence to vitamin d supplementation. For vitamin d deficiency: I was feeling fine until i was diagnosed with vitamin d deficiency (4,6). But for people with darker skin, (Meaning trying to get vitamin d from the sun during a lunch break is all but impossible). Older people who are confined indoors may have vitamin d deficiency even at this intake level. Safety data of high vitamin d doses in older children and adolescents are quite limited.