Product name: Zahler, Milk Thistle, Silybum Marianum, 60 Vegetable Capsules
Quantity: 60 Count, 0.06 kg, 9.7 x 5.1 x 5.1 cm
Categories: Zahler, Herbs, Homeopathy, Milk Thistle Silymarin, Kosher, Dairy Free, Casein Free, Soy Free
Advanced Nutrition by Zahler, Silybum Marianum, Powerful Liver Tonic, General Heath, Dietary Supplement, Feel Better, Everyday, Kosher Pareve, Dairy Free, Soy Free, Powerful Liver Tonic, The liver is essential for digestion, detoxification, blood sugar regulation and fat metabolism. Zahler’s Milk Thistle helps to support healthy liver cells and the body’s natural repair processes. It also has natural antioxidant activity.
The products on this website are herbal dietary supplements and contain no pharmaceuticals or synthetic chemical ingredients. Here are 7 science-based benefits of milk thistle. Traditional chinese medicine (Tcm) is a range of traditional medical practices originating in china that developed over several thousand years. Adding the silymarin supplement livergol to standard rheumatoid arthritis drug therapy was reported to significantly improve various disease severity parameters. We will outline below, herbs and foods which reduce fatty liver as part of the liver detox program. In test-tube and animal studies, silymarin has been shown to prevent oxidative damage to brain cells, which could help prevent mental decline (16, 17). This study also showed that silymarin does not stimulate cell growth in the hela, burkitt lymphoma, and human hepatoma cell lines.
Zahler, Milk Thistle, Silybum Marianum, 60 Vegetable Capsules: Milk Thistle Silymarin, Homeopathy, Herbs
Only at very high concentrations was cell viability affected by silymarin in hepg2 cells. Native americans use milk thistle to treat boils and other skin diseases. The german commission e recommends milk thistle use for dyspeptic complaints, toxin-induced liver damage, hepatic cirrhosis, and as a supportive therapy for chronic inflammatory liver conditions. Patients either had the silymarin gel or a placebo gel starting on the first day of radiotherapy treatment and continuing for the full 5 weeks of treatment. Findings from one of the best studies of milk thistle to date suggest it’s reputation as an antidote to liver ailments may be overstated. According to research conducted by the original manufacturer and primary researcher of milk thistle extract, madaus ag of cologne, germany, this level of concentration of silymarin is required to survive degradation by gastric fluids and in order to enter into the bloodstream via the intestinal wall. To avoid complications, always advise your doctor about any supplements or herbal remedies you are taking. Most of the silymarin is concentrated in the protein layer of the seed husk (Pericarp). Intense research activity has been dedicated to the identification of natural products from traditional medicine that regulate abca1 expression.
Other studies have investigated the use of milk thistle in patients with hyperlipidemia, diabetes, and amanita phalloides (Fr). A case report from australia described a reaction to a milk thistle extract that included intermittent episodes of sweating, abdominal cramping, nausea, vomiting, diarrhea, and weakness. There is strong preclinical evidence for silymarin’s hepatoprotective and anticarcinogenic effects, including inhibition of cancer cell growth in human prostate, skin, breast, and cervical cells. Dioscorides (Ad 40 to 90), a greek physician and botanist, was the first to describe the healing properties of milk thistle. Overall, more high-quality research is needed to define the doses and clinical effects of this fascinating herb. Studies have found that silymarin reduces transcription of markers of tumor promotion and activity, inhibits transcription of tumor promoters, interferes with cell signaling, inhibits inflammatory actions, and modulates cell-cycle regulation. Purposemilk thistle, an herbal compound, is the dietary supplement taken most frequently by patients with chronic liver disease.
Several studies have suggested that milk thistle may be beneficial for people with diabetes, most notably in those with type 2 diabetes. By clearing undigested, built up matter from the colon, an ultimate herbal detox program with a high dose of herbs will reduce the amount of re-circulating waste substances straining the liver. Research studies conducted in the laboratory have investigated the properties of silymarin or it’s isomer silybin using cell lines and animal models. Nature’s way standardized milk thistle is non-gmo project verified. The major constituents of silymarin are the three diastereomeric pairs, silybins a and b (Also called silibinin), isosilybins a and b, silychristin, isosilychristin, and silydianin. Agents used in naturopathy must exist in nature, with no chemical additives, and have undergone no or very little processing, such as herbs, nutrients, diet supplements, etc. They suggest that a substance in milk thistle (Silymarin) can protect the liver from damage caused by viruses, toxins, alcohol, and certain drugs such as acetaminophen (Tylenol). One study in breast cancer patients, looked at applying silymarin gel to the skin on the chest wall following a mastectomy and during radiotherapy treatment.
More evidence is needed to prove that milk thistle benefits human livers in the same way. The milk thistle of commerce is a standardized preparation extracted from the fruits (Seeds) of silybum marianum (L). Early colonists introduced milk thistle to north america. It found that cholesterol levels were lower in people taking milk thistle to treat diabetes than those taking a placebo. The herb has been used since greco-roman times to treat liver problems. We do not yet have enough research to know whether milk thistle may affect cancer treatments and make them more or less effective. On rare occasion, milk thistle can cause a potentially life-threatening, all-body allergy known as anaphylaxis. The most common use of milk thistle is for liver problems. Their inclusion should not be viewed as an endorsement of the content of the websites, or of any treatment or product, by the pdq integrative, alternative, and complementary therapies editorial board or the national cancer institute. Summary milk thistle extract may help protect the liver against damage caused by disease or poisoning, though more research is needed. It must contain not less than 2% of silymarin, calculated as silybin, as determined by a usp spectrophotometric assay method. Pharmacopeial grade milk thistle consists of the dried ripe fruit of s. It is not known whether milk thistle may reduce, enhance, or have no impact on the effectiveness of chemotherapy.
Zahler Milk Thistle Silymarin
Studies have also investigated the effect of silymarin on tumor initiation and promotion. Raloxifene: Coadministration of milk thistle and raloxifene may lead to 4- to 5-fold increases in raloxifene systemic exposure due to inhibition of intestinal glucuronidation by silybin a and silybin b. It also looks at how to use milk thistle and whether there are any risks to consider. In follow-up, silymarin use was associated with reduced progression of fibrosis to cirrhosis but without an impact on clinical outcome. Core tip: We discuss recent experiences in administrating natural medicines to treat liver problems, and the adverse reactions of some natural medicines. Some animal studies have shown that milk thistle could be useful for reducing the side effects of cancer treatments (26, 27, 28). The content of silymarin is calculated as silybin. To be honest i cannot tell the difference between this and the milk thistle i was buying on the uk high street – except this one is about a quarter of the price – even when that high street giant is having one of it’s regular special offer sales! After three months of treatment (525 Mg/day of silymarin), chronic hepatitis was found to be significantly improved bioptically. According to the german commission e, there are no reported side effects with milk thistle when the recommended doses are used.
Ingredients: Grain alcohol (67-77%), Distilled water and milk thistle extractives. Then, during the middle ages, milk thistle was recommended to treat liver toxicity. This indicates that silymarin has anti-inflammatory and antiviral effects in patients with chronic hepatitis c. It has been used as a medicine for over 2,000 years as milk stimulant, for liver, kidney and spleen problems, for jaundice, gall stones, and menstrual pain. In the present study, the electro homoeopathic medicines scrofoloso 5 (S5) and original research article babu et al. According to a comprehensive review of studies in the american journal of gastroenterology, milk thistle neither improves liver function nor reduces the risk of death in people with alcoholic liver disease, hepatitis b, or hepatitis c. The botanical name for milk thistle is silybum marianum (L). They suggest that a substance in milk thistle (Silymarin) can protect the liver from damage caused by viruses, toxins, alcohol, and certain drugs, such as acetaminophen. No significant adverse effects were associated with silymarin.
An older study found that milk thistle extract had a positive effect on immune response in humans. A formula composed of two or more drugs has been demonstrated as more beneficial for disease treatment, but the selection of individual herbs in the formula must be strictly guided by the principles underlying chinese herbal medicine. In patients with hepatitis c, beneficial effects have not been noted with use of silymarin. If you have liver disease, do not take any over-the-counter medication, herbs, or supplements without checking with your doctor first. Given the limited amount of human data, the use of milk thistle/ silymarin as a treatment for cancer patients cannot be recommended outside the context of well-designed clinical trials. Scientists think this creates a detoxifying effect, which is why it is milk thistle may be beneficial for liver problems. In rats with azoxymethane-induced colon cancer, dietary silymarin resulted in a reduction in the incidence and multiplicity of adenocarcinoma of the colon in a dose-dependent manner. Summary milk thistle is generally considered safe. Gaertner pharmacopeial name: Cardui mariae fructus other names: Blessed milk thistle, st. Nonsteroidal anti-inflammatory drugs (Nsaids), such as naproxen or aleve, and ibuprofen, motrin, or advil, can also damage the liver, as can some herbs and supplements. About a third of people battling hepatitis c infection say they have tried milk thistle capsules, extracts or powders, a figure that helps explain the roughly $100 million in annual sales of the products.
Zi x, feyes dk, agarwal r: Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells mda-mb 468: Induction of g1 arrest through an increase in cip1/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins. Therefore, when administrating naturopathic protocols to patients for the treatment of liver diseases, we should try our best to prevent and avoid as much as possible the negative impact of these medicines. Although there are many reports on the use of herbals for the treatment of chronic liver diseases, most treatment trials have suffered from poor scientific design, uncertainty about the required dosage of herbals, and an insufficient number of study participants. D patients were randomly assigned to the misoprostol and silymarin groups. However, it must contain not less than 1,5% silymarin, calculated as silybin with reference to the dried drug. Natural medicine is a system of therapy that administrates natural agents and their derivatives to treat human diseases.