Product name: Country Life, P-5-P (Pyridoxal 5′ Phosphate), 50 mg, 100 Tablets
Quantity: 100 Count, 0.14 kg, 5.1 x 5.1 x 8.9 cm
Categories: Country Life, Supplements, Vitamins, Vitamin B, B6 Pyridoxine, Certified Gluten Free, Gluten Free, Kosher Parve
Established 1971, Certified Gluten-Free, Supports Energy, Supports Nervous System Health, Active Form of B6, Dietary Supplement, Kosher Parve, — Our Pledge of Integrity —, Authenticity, Cleanliness, Freshness, Consistency, Accuracy, Vitamin B6 helps metabolize lipids, carbohydrates, and proteins into energy. It also supports the function and growth of red blood cells as well as supporting the nervous and immune systems. P-5-P is a biologically active form of vitamin B6 and is utilized by the body.
A small amount of vitamin b 6 is also excreted in the feces. A vitamin b6 deficiency most often occurs when other b vitamins in the body are low, particularly vitamin b12 and folic acid. If vitamin b6 deficiency is particularly severe, convulsions may occur as a result of excessive neural stress. In some cases, as much as 1,000 mg of vitamin b6 per day (A potentially toxic level) has been used successfully. Individuals with borderline vitamin b6 concentrations or mild deficiency might have no deficiency signs or symptoms for months or even years. Deficiencies of iron, vitamin b12, and folic acid are the most common nutritional causes of anemia. Other neurologic symptoms observed in severe vitamin b 6 deficiency include irritability, depression, and confusion; additional symptoms include inflammation of the tongue, sores or ulcers of the mouth, and ulcers of the skin at the corners of the mouth. Evaluating the impact of vitamin b6 from many of these trials is challenging because these studies also included folic acid and vitamin b12 supplementation. There is some evidence that taking pyridoxine by mouth may improve pms symptoms, such as breast pain, depression, or anxiety in some women. Each nutrient in the b vitamin complex performs a unique role in maintaining proper metabolic functioning and is essential for well-being. As we stated earlier, vitamin b6 is frequently associated with other supplement products.
Country Life, P-5-P (Pyridoxal 5′ Phosphate), 50 mg, 100 Tablets: B6 Pyridoxine, Vitamin B, Vitamins, Supplements
However, using vitamin b6 to prevent or treat depression has not been shown to be effective (11, 12). Those suffering with carpal tunnel syndrome have consistently found relief in symptoms by using vitamin b 6, many find b 6 useful for tendonitis and other joint pain. I have used other brands (I worked in a health supplement store – major chain, which i will not mention) and comparably the price is very economical and it does produce results. It has been previously suggested that vitamin b6 might play a role in the prevention of pre-eclampsia and possibly preterm birth. The plp-dependent transaminases and glycogen phosphorylase provide the vitamin with it’s role in gluconeogenesis, so deprivation of vitamin b 6 results in impaired glucose tolerance. She had nerve damage in her back legs which we treated with accupuncture and vitamin b injections. It has also been proposed that vitamin b 6 could provide antioxidant effects.
Vitamin b6 is also known to reduce elevated urinary oxalate in some stone formers who are not necessarily b6 deficient. What happens if i take too much vitamin b6? In a preliminary study, 22 women with recurrent miscarriages who had elevated levels of homocysteine were treated with 15 mg per day of folic acid and 750 mg per day of vitamin b6, prior to and throughout their next pregnancy. Yet, a prospective study that followed nearly 500,000 older adults for nine years observed that the risk of esophageal and stomach cancers was lower in participants in the highest versus lowest quintile of total vitamin b 6 intakes (Median values, 2,7 mg/day vs. Taking more than 50 milligrams (Mg) of vitamin b6 a day has been linked to side-effects such as a loss of feeling in your hands and feet (Peripheral neuropathy). The participants were given either a b-vitamin complex with folic acid, b12, and b6; folic acid and b12; 40 mg b6 alone; or a placebo. In hiv-positive people with b-vitamin deficiency, the use of b-complex vitamin supplements appears to delay progression to and death from aids.
The vitamin program included large amounts of various b vitamins, as well as vitamin c and vitamin e. A three-month study in over 60 premenopausal women found that taking 50 mg of vitamin b6 daily improved pms symptoms of depression, irritability and tiredness by 69%. While commonly purchased in pill form, they are also available as an effervescent, liquid, chewable, and gummy supplement. Vitamin b6 helps the body make several neurotransmitters, chemicals that carry signals from one nerve cell to another. Research indicates that this surgery increases a person’s need for b-12, there is further evidence that many people need a multivitamin that includes b vitamins and other nutrients after this surgery, at least in the short term. Sensory neuropathy from pyridoxine abuse. E, a methionine load test), But vitamin b 6 supplementation might not be effective in decreasing fasting levels of homocysteine. 84 It is not known whether supplementing with these vitamins would help prevent miscarriages in women with normal homocysteine levels. However, only take very high doses of b vitamins under a doctor’s guidance. Muscle damage in people with this disease may cause dark urine and vitamin b6 deficiency. However, the small number of clinical trials completed to date has not shown that vitamin b6 supplementation can help prevent cancer or reduce it’s impact on mortality.
Vitamin b6 is an indispensable nutrient essential to maintaining physical and mental health, as we get older in life. For nausea and vomiting of pregnancy, the following doses of vitamin b6 have been taken by mouth: 25 Milligrams every eight hours for 72 hours; 10 milligrams of pyridoxine hcl every eight hours for five days; and 100 milligrams daily for seven days. Controlled trial of pyridoxine in the treatment of premenstrual syndrome. Really, it seems from the literature that b6 excess may now exceed the incidence of b6 deficiency, primarily because of supplementation. However, studies have not proven the effectiveness of b6 in improving brain health. Oral contraceptives can deplete the body of vitamin b6, a nutrient needed for maintenance of normal mental functioning. Penicillamine may increase vitamin b6 excretion, reduce activity, and increase the risk for vitamin b6 deficiency. These studies involved subjects who had generally been on the supplements for five to six months or less. Women on low-dose birth control taken by mouth may have lower levels of the vitamin. Specifically, the risk of having serum crp levels greater than 10 mg/l (Corresponding to high inflammatory activity) was 57% higher in individuals with vitamin b 6 intakes lower than 2 mg/day compared to those with intakes equal to and above 5 mg/day. 139 A number of other small, preliminary trials have not demonstrated an effect of either oral or injected vitamin b6 on prolactin levels, 140, 141, 142, 143, 144 and they also have reported inconsistent effects on restoring menstruation.
Country Life B6 Pyridoxine
Finally, although high doses of vitamin b 6 (Pyridoxine) have demonstrated no benefit in preventing the risk of side effects from ocs, The use of vitamin b 6 supplements may be warranted in current and past oc users. Skin inflammation or itching may be indicators of an intolerance to vitamin b6 supplements or one of their components. This is one of the most popular b vitamins to be taken on it’s own, with millions of women choosing to take it during their monthly cycle, often along with evening primrose oil. For heart disease (High homocysteine levels), 40 milligrams of vitamin b6 has been taken by mouth daily. 160 Attempts to lower homocysteine by simply changing the diet rather than by using vitamin supplements have not been successful. At nature made, we are committed to finding the perfect combination of vitamins and supplements for a healthier, more vibrant you. And do not you love when a supplement has no fillers? 46 In another trial, asthmatic adults experienced a dramatic decrease in the frequency and severity of asthma attacks while taking 50 mg of vitamin b6 twice a day. Carpal tunnel syndrome and vitamin b 6 therapy. I really think that vitamin b6 is most essential for the central nervous system. Years ago, researchers discovered that animals who were deficient in vitamin b6 could not properly process msg.
These studies suggest that vitamin b6 is effective in treating morning sickness even in durations of less than one week. High doses of nicotinamide, another form of vitamin b-3, can cause diarrhea and increased bleeding. The fortified product provided daily 130 mg of eicosapentaenoic acid and 200 mg of docosahexaenoic acid (Epa and dha, two fatty acids in fish oil), small amounts of supplemental vitamin e, folic acid, and vitamin b6, and additional amounts of oleic acid and alpha-linolenic acid. Notably, in a minority of studies of both vitamin b 12 and combinations of b vitamins that include vitamin b 12 compared with placebo, the b vitamin treatment resulted in worse performance on a small number of cognitive tests. One pathway relies on the vitamin b 12-dependent methionine synthase and the methyl donor, 5-methyl tetrahydrofolate (A folate derivative), to convert homocysteine back to methionine. Low blood levels of folic acid and vitamin b12 are also common in hiv-positive people. Adverse effects have been documented from vitamin b 6 supplements, but never from food sources. Vitamin b6 has been used in combination with niacin in the treatment of schizophrenia with some reported benefits.
Summary some observational studies suggest a link between adequate dietary intake and blood levels of vitamin b6 and a decreased risk of certain types of cancer, but more research is needed. 218 Most physicians would consider reasonable daily amounts of these nutrients for adolescents to be 15 mg of zinc, 5 to 10 mg of manganese, and 25 mg of vitamin b6, larger amounts might be used with medical supervision. Supplementing with this vitamin contributes weight loss and helps maintain body mass within a healthy range. One controlled study revealed that taking anticonvulsant drugs dramatically reduces blood levels of vitamin b6, a nutritional deficiency of vitamin b6 can lead to an increase in homocysteine blood levels, which has been associated with atherosclerosis. As such, dietary inadequacies are one of the key causes of vitamin b deficiency. However, much more research is needed to confirm whether vitamin b6 can treat or prevent these conditions. Research on vitamin b6 and breast cancer also shows an association between adequate blood levels of b6 and a decreased risk of the disease, especially in postmenopausal women.
Evidence is conflicting in support of vitamin b6 for bone protection. The effect of topical application of pyridoxine ointment on the rate of sebaceous secretion in patients with seborrheic dermatitis. Most people get enough vitamin b6 through their diet, but certain populations may be at risk for deficiency. The linus pauling institute recommends that older adults take a multivitamin/mineral supplement, which provides at least 2,0 mg of vitamin b 6 daily. A general multivitamin-mineral formula can reduce the detrimental health effects of these deficiencies. Evidence is lacking to support the use of vitamin b6 for breast pain or tenderness. Amounts of vitamin b6 used to successfully reduce reactions to sunlight have varied considerably.
Country Life, P-5-P (Pyridoxal 5′ Phosphate), 50 mg, 100 Tablets Product Review
Very good. Product ok! Activated B6. P5p. excellent product. May boost AAAD and suppprt brain health. Eat before exercise. ambiguous. P5P. It works
I like it its good
Very happy, quality price nothing to say. no negative effect, I will buy again.
This is a high quality B6 supplement which helps get rid of breast pain.
Highly efficient supplement for me. It has a very positive influence on my sleep patterns and works much better than conventional Vitamin B6.50 mg is a good dosage.
I take this in conjunction with St Johns Wort or Macuna Pruriens or D Phenyl Alanine to boost either dopamin or serotonin. But AAAD, an important brain enzyme, maybe depleted by taking the above supplements. P5P, a form of vitamin B6, may help prevent AAAD depletion but I have no proof or even strong evidence this is actually happening. I will continue to take low doses of P5P on faith.
Eat well and eat several times before fasting or exercising. It is definitely less tired.
Unfortunately, controversial for me drug. of the benefits 1. the skin really improves, the main thing is the faces, irritations disappear, the color levels out, the effect came quickly enough in 7 days 2.2. more energy 3. it becomes easier to breathe through the nose from the minuses: 1. I am hypotensive, falls off The pressure on 10 points is a lot for me, although I divided the pill into 4 parts and drank 1/4 a day.2. took mostly about arrhythmias, for some reason the opposite effect appeared – in the evenings the arrhythmia increased. I tried several times, each time the same thing (I will try again, at least for a week – I really like the effect on the skin; drink to see the improvement on the face (although this is a bonus, I drink for the joints).
Can’t help with a review as yet as haven’t finished the previous bottle – another brand- so it is still untouched!
It seems to do what it should.
Questions and Answers
It states in the description: pyridoxal 5′ phosphate 34 mg. Then it states:Pyridoxal 5′ Phosphate 50 mg. So what is it: 34mg or is it 50mg?
How soon after starting this did you notice results?
Hi, The difference in the numbers has to do with the amount of active B6 verses the amount of B6 as the phosphate. Active B6 can not be added to a formula unless it is in the phosphate form. So it is 34 mg active B6 which is actually 50 mg B6 phosphate. The label says: VITAMIN B6 (as pyridoxal 5′ phosphate) 34 mg and pyridoxal 5′ phosphate 50 mg (no B6 mentioned in the latter number) The first number describes vitamin VITAMIN B6 and the second number B6 as the phosphate. Although I have not checked, I would guess that all P-5-P products are manufactured in the manner (to contain 34 mg active B6). I hope this helps.
I never “noticed” results. I take this daily because I have faith in the overwhelming evidence that it is beneficial to do so.