Product name: Solgar, Milk Thistle Herb Extract, 150 Vegetable Capsules
Quantity: 150 Count, 0.32 kg, 7.1 x 7.1 x 12.7 cm
Categories: Solgar, Herbs, Homeopathy, Milk Thistle Silymarin, Dairy Free, Casein Free, Vegetarian, Kosher Parve
PhytO2X System, Since 1947, Standardized, Full Potency, (Silybum Marianum), Herbal Supplement, Gluten, Wheat and Dairy Free, Suitable for Vegetarians, Kosher Parve, Solgar’s Standardized Full Potency (SFP) Herbs are developed through a unique process that integrates the ideologies of both traditional herbalism and standardized herbal technology. To ensure consistent and reliable phytonutrient levels, we isolate a controlled amount of these important active plant compounds. Then we blend these enhanced, “standardized” compounds with all of the components that occur naturally in the whole raw herb. The result is a potent, premium-quality standardized herbal extract with all of the synergistic and beneficial qualities found in nature.
We will outline below, herbs and foods which reduce fatty liver as part of the liver detox program. However, studies are mixed as to whether milk thistle improves liver function tests or quality of life for people with chronic active hepatitis b or c. Due to it’s antioxidant and anti-inflammatory effects, milk thistle may be a useful supplement for people with acne. An additional useful source for information on some otc supplements and herbs is the national library of medicine. First, because they are much less regulated than prescription medicines, the make-up, amount of active ingredients, and strength of different supplements can vary quite a bit between brands or suppliers, or over time from a single supplier, though certification by the us pharmacopeial convention, a non-governmental group, provides some reassurance about the contents of otc supplements and herbs. Purposemilk thistle, an herbal compound, is the dietary supplement taken most frequently by patients with chronic liver disease. The german commission e recommends milk thistle use for dyspeptic complaints, toxin-induced liver damage, hepatic cirrhosis, and as a supportive therapy for chronic inflammatory liver conditions. The name milk thistle comes from the story of the virgin mary who was sheltering under the thorny leaves of the milk thistle while nursing baby jesus.
Solgar, Milk Thistle Herb Extract, 150 Vegetable Capsules: Milk Thistle Silymarin, Homeopathy, Herbs
Most of the silymarin is concentrated in the protein layer of the seed husk (Pericarp). This article highlights the current practice and recommended improvement of natural medicines in the treatment of liver diseases and gives some specific examples to emphasize the prevention and management of adverse reactions of the natural agents and suggests that natural medicine should be cautiously used to treat liver problems. Some evidence exists about the positive impact of these milk thistle compounds on bone density in rats and mice that have undergone ovariectomy. Health canada has registered two milk thistle products in the herbs and natural products category, a liquid preparation and a capsule, and four milk thistle products in the homeopathic category, including liquid, pellet, globule, granule, and tablet formulations. In a study of rats receiving ethanol during specific weeks of the gestational period, coadministration of silymarin with ethanol resulted in no deficits in spatial working memory in rats on postnatal day 60, suggesting silymarin provided a protective effect against alcohol-induced learning issues. Because of the relative convenience, safety and efficacy, natural medicine is now increasing worldwide. However, when silymarin was combined with these agents, serum indices and hepatic markers were reduced.
When reported, side effects for milk thistle are generally gut disturbances like diarrhea, nausea or bloating. In a multicenter, double-blind, placebo-controlled trial, 154 patients with chronic hepatitis c and elevated alt levels who were unsuccessfully treated with interferon, silymarin 420 mg or 700 mg 3 times daily for 24 weeks did not significantly reduce alt levels. More research needs to be carried out before a definitive list of milk thistle benefits can be confirmed. The effect of silymarin on capecitabine-induced hand-foot syndrome was evaluated in 40 patients with gi cancer in a double-blind, randomized, placebo-controlled trial. In ovariectomized rats, treatment for 12 weeks with silymarin prevented bone loss, either through increasing formation via an effect on calcium, phosphorus, osteocalcin, and parathyroid hormone, or through direct action with estrogen receptor-beta. There are no guidelines directing the appropriate use of milk thistle. Alternatively, this may be related to the effect of silymarin on detoxification systems. In a double-blind, placebo-controlled trial, 50 children who were undergoing treatment for acute lymphoblastic leukemia, and who had chemotherapy -related hepatotoxicity, were randomly assigned to receive silymarin or placebo for a 4-week period. Studies have shown improvements in liver function in people with liver diseases who have taken a milk thistle supplement, suggesting it could help reduce liver inflammation and liver damage.
But now more evidence has come in: In a careful, double-blinded study financed by the national institutes of health, researchers at the university of north carolina found that milk thistle had no real effect on people with chronic hepatitis c. In traditional chinese medicine, milk thistle is referred to as da ji, while the seeds are called shui fei ji. A focus on chinese traditional medicine in hepatitis c virus. The commission e approved the internal use of crude milk thistle fruit preparations for dyspeptic complaints. The chinese herb bupleurum has anti-inflammatory properties and has been used historically to treat liver disorders. The use of herbs is a time-honored approach to strengthening the body and treating disease. Results: In traditional medicine, silybum marianum has been introduced as harshfe barry and uses for the treatment of liver, gallbladder, and skin diseases, swelling, and strengthening digestion; today, in many studies, the effects of this plant have been studied, and properties, such as treatment of liver, kidney, and skin diseases, blood glucose control and lipid metabolism, strengthening the immune system and it’s anticancer effects have been proven. Testing methods for the content of silymarin components is being set up at the food development centre in portage la prairie. Although more research is needed on how it works, milk thistle is thought to reduce damage to the liver caused by free radicals, which are produced when your liver metabolizes toxic substances.
As with any medicinal herb crop, quality control is essential to achieve a good selling price, particularly in the face of the anticipated intense competition in the next few years. Although it is possible that milk thistle may play a part in treating liver disease and some types of cancer there is currently not enough evidence for this. Talk to your doctor before taking any herb or supplement if you have liver disease. 70% Of the extract weight such that a 200 mg tablet contains 140 mg of silymarin, or 200 – 400 mg per daily dose. Although the therapeutic effect of herbs is beneficial, side effects must be treated with the greatest possible care. To avoid complications, always advise your doctor about any supplements or herbal remedies you are taking. Therefore, the main challenge of this review is to discuss the diverse molecular mechanisms for silymarin antiproliferative and apoptotic effects; most of them largely studied in various types of cancers so far. An adverse reaction to the herbal medication milk thistle (Silybum marianum). Summary milk thistle is generally considered safe. People with acne often experience improvement when they increase the efficiency of their liver with an herbal cleanse.
Solgar Milk Thistle Silymarin
Sixty women in the psychiatric ward of an italian hospital were selected for the trial, all having been treated with either phenothiazines and/or butyrophenones for at least five years. In a pilot, randomized, double-blind, placebo-controlled clinical trial, hospitalized patients receiving cisplatin were administered placebo or oral silymarin 420 mg/day in 3 divided doses starting 1 to 2 days prior to cisplatin initiation and continuing through the end of 3 cycles of 21-day chemotherapy. One study in breast cancer patients, looked at applying silymarin gel to the skin on the chest wall following a mastectomy and during radiotherapy treatment. The event was not an accident, but the inevitable result of western medicine physicians administrating chinese medicine without applying the underlying principles of traditional chinese medicine theory in japan. You will see very noticeable differences in your health when you pay attention to the foods and herbs that benefit your liver. Then, during the middle ages, milk thistle was recommended to treat liver toxicity. It has been used as a medicine for over 2,000 years as milk stimulant, for liver, kidney and spleen problems, for jaundice, gall stones, and menstrual pain. Chinese medicinal herbs for asymptomatic carriers of hepatitis b. Complementary and alternative medicine in chronic liver disease. The exceptional benefits of milk thistle are due to it’s antioxidant properties, which help to optimize health and well being.
According to the survey, people with hepatitis c reported fewer symptoms and a somewhat better quality of life when taking milk thistle despite having no measurable change in viral activity or liver inflammation. If you have cirrhosis, your doctor will use caution when prescribing medications because many medicines cause complications in people with liver disease. Many of the medical and scientific terms used in this summary are hypertext linked (At first use in each section) to the nci dictionary of cancer terms, which is oriented toward nonexperts. The active constituents of this herb such as flavonoids and caffeoylquinic acid may be responsible for this effect. Summary initial test-tube and animal studies have shown that milk thistle has some promising characteristics that could make it useful for protecting brain function. Given the limited amount of human data, the use of milk thistle/ silymarin as a treatment for cancer patients cannot be recommended outside the context of well-designed clinical trials. Given the limited amount of human data, the use of milk thistle/silymarin as a treatment for cancer patients cannot be recommended outside the context of well-designed clinical trials. Different parts of the milk thistle plant may be used to treat various health conditions. Patients in a phase i pharmacokinetics study for the evaluation of absorption characteristics and determination of effective doses received increasing oral doses of silymarin.
More studies are needed before it can be determined how silymarin might be used to support people undergoing cancer treatment. A study on mice found milk thistle extract helped to reduce insulin resistance. The ancient greek and romans used milk thistle for snake bites. Ten randomized trials have been reported in patients with hepatitis or cirrhosis, and one randomized trial has reported the use of silymarin as a prophylaxis to iatrogenic hepatic toxicity. Although many of these studies have produced encouraging results, none of the findings have been replicated in human clinical trials. Laboratory data suggest that silymarin and silybin protect the liver from damage induced by toxic chemicals. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. One source suggests daily doses of 12 to 15 g of dry fruits for dyspepsia and disorders of the biliary system, while an extract containing 200 to 400 mg/day of silymarin is considered effective in various liver disorders. In follow-up, silymarin use was associated with reduced progression of fibrosis to cirrhosis but without an impact on clinical outcome.
Neopterin, a marker of cellular immune system activation, and tnf-alpha were decreased in both groups after silymarin therapy, whereas production of interferon-gamma and il-4 were increased. Other studies have investigated the use of milk thistle in patients with hyperlipidemia, diabetes, and amanita phalloides (Fr). Silybin and silymarin have been studied in the treatment of aging skin and rosacea, as well as in skin cancer prevention. There are mixed data regarding milk thistle’s ability to exert inhibitory or inductive activity on cytochrome p450 (Cyp-450) 1a2, 2c19, 2d6, 2e1, and 3a4, as well as p-glycoprotein. Analysis of characteristics of traditional chinese medicine and western medicine clinical use in patients with viral hepatitis based on real world hospital information system data. Milk thistle may have estrogen-like effects, so people with hormone-sensitive conditions should use this herb with caution. But are there any proven health benefits of milk thistle? This article explores 10 potential milk thistle benefits and examines whether there is any scientific evidence to support it’s use.
The active ingredients in milk thistle are a group of plant compounds collectively known as silymarin.