Product name: Solgar, Milk Thistle, 250 Vegetable Capsules
Quantity: 250 Count, 0.43 kg, 14.7 x 7.9 x 7.9 cm
Categories: Solgar, Herbs, Homeopathy, Milk Thistle Silymarin, Vegetarian, Dairy Free, Casein Free
Since 1947, (Silybum Marianum), Dietary Supplement, Suitable for Vegetarians, Gluten, Wheat and Dairy Free, K-Parve, Full Potency Herbs, Solgar’s Full Potency Herbs include traditional herbal extracts in a base of active raw herbs to ensure that the full benefits are derived from the herbs. These products combine the advantages of both raw herbs and their active principles in the form of dry extracts. Our herbal formulas are specially prepared to include all the naturally occurring, synergistic constituents of the herb and not just selected, isolated, active phytochemicals. Solgar’s herbal products offer the highest quality, purest herbs available worldwide.
It is always a good idea to speak to a healthcare professional before starting to use milk thistle or any other supplement, as it may interact with other medications or conditions. Evidences for antiosteoporotic and selective estrogen receptor modulator activity of silymarin compared with ethinylestradiol in ovariectomized rats. In fact, a survey funded by the national institutes of health reported that 23 percent of 1,145 people with hepatitis c used herbal supplements, with milk thistle being by far the most common. This study also showed that silymarin does not stimulate cell growth in the hela, burkitt lymphoma, and human hepatoma cell lines. On rare occasion, milk thistle can cause a potentially life-threatening, all-body allergy known as anaphylaxis. Added text to state that the impact of silymarin and it’s components on signaling pathways have been investigated in several studies; in in vitro and in vivo studies utilizing the sk-mel-5 melanoma cell line, silybin significantly inhibited growth through it’s direct binding with mek1/2 and ribosomal s6 kinase-2, resulting in the inhibition of catalytic kinase activities (Cited lee et al. One study in breast cancer patients, looked at applying silymarin gel to the skin on the chest wall following a mastectomy and during radiotherapy treatment.
Solgar, Milk Thistle, 250 Vegetable Capsules: Milk Thistle Silymarin, Homeopathy, Herbs
More research is needed to confirm these results and the safety of milk thistle for breastfeeding mothers (38, 39, 40). Many of the medical and scientific terms used in this summary are hypertext linked (At first use in each section) to the nci dictionary of cancer terms, which is oriented toward nonexperts. Further research on humans is needed to identify what benefits a person can expect from applying milk thistle to their skin. Specifically, silymarin has been shown to stimulate the glutathione s-transferase pathway and alter the intracellular concentration of glutathione (A potent antioxidant). If drinking milk thistle tea, it is best to limit intake to 6 cups a day. To be honest i cannot tell the difference between this and the milk thistle i was buying on the uk high street – except this one is about a quarter of the price – even when that high street giant is having one of it’s regular special offer sales! This suggests milk thistle may be beneficial for those looking to lose weight. But are there any proven health benefits of milk thistle? Fewer chemotherapy dose reductions were observed in the silymarin group compared with the placebo group; however, the difference was not significant. The use of silymarin in the treatment of liver diseases.
As an antioxidant, silymarin provides support for quenching free radicals, thus protecting against lipid peroxidation. Complementary and alternative medicine in hepatology: Review of the evidence of efficacy. Most clinical trials of milk thistle have been conducted in patients with either hepatitis or cirrhosis. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. A formula composed of two or more drugs has been demonstrated as more beneficial for disease treatment, but the selection of individual herbs in the formula must be strictly guided by the principles underlying chinese herbal medicine. One reported effect of milk thistle is that it can boost breast milk production in lactating mothers. Use of milk thistle or it’s active components as adjunctive therapy to prevent chemotoxicities associated with chemotherapy and/or radiation has been studied. Silybin and silymarin have been studied in the treatment of aging skin and rosacea, as well as in skin cancer prevention. More research on humans is needed to confirm the effects of milk thistle on cognition. Chinese herbal medicine and interferon in the treatment of chronic hepatitis b: A meta-analysis of randomized, controlled trials.
But now more evidence has come in: In a careful, double-blinded study financed by the national institutes of health, researchers at the university of north carolina found that milk thistle had no real effect on people with chronic hepatitis c. Toxic effects of silymarin have not been noted clinically at a dosage of 1,200 mg/day; however, mild allergies have been reported with dosages greater than 1,500 mg/day. This cancer information summary provides an overview of the use of milk thistle as a treatment and adjunct agent for people with cancer. A primary use for silymarin is in the treatment of liver damage due to ingestion of alcohol. Agents used in naturopathy must exist in nature, with no chemical additives, and have undergone no or very little processing, such as herbs, nutrients, diet supplements, etc. One of the most common uses of milk thistle is to treat liver problems. A survey of chinese herbal ingredients with liver protection activities. The tincture should be bright yellow, indicating the presence of the resinous fraction which contains the silymarin. The researchers found that the silymarin gel reduced the severity of the radiodermatitis and delayed it’s occurence after 5 weeks of application.
More research is needed to see if silymarin benefits asthma symptoms in humans. Although natural medicine is beneficial and safe, physicians should pay close attention to the potential side-effects of the naturopathic agents, which lead to liver injury, interstitial pneumonia and acute respiratory failure. Rare cases of milk thistle producing a laxative effect have been reported. According to the german commission e, there are no reported side effects with milk thistle when the recommended doses are used. In laboratory studies, silymarin has been found to stabilize cell membranes, thus preventing toxic chemicals from entering the cell. Zhao j, agarwal r: Tissue distribution of silibinin, the major active constituent of silymarin, in mice and it’s association with enhancement of phase ii enzymes: Implications in cancer chemoprevention. People who are allergic to ragweed may have an allergic reaction to milk thistle. Of the 170 patients, 87 received 420 mg of silymarin daily, compared with 83 placebo patients. Natural medicine is a holistic approach to treat liver diseases. You can also purchase milk thistle products online.
Solgar Milk Thistle Silymarin
No significant adverse effects were associated with silymarin. In a study of rats receiving ethanol during specific weeks of the gestational period, coadministration of silymarin with ethanol resulted in no deficits in spatial working memory in rats on postnatal day 60, suggesting silymarin provided a protective effect against alcohol-induced learning issues. At present, there is not enough scientific data to say whether milk thistle can help the liver or not. This article highlights the current practice and recommended improvement of natural medicines in the treatment of liver diseases and gives some specific examples to emphasize the prevention and management of adverse reactions of the natural agents and suggests that natural medicine should be cautiously used to treat liver problems. Do not use ultimate herbal health products if you are allergic to any of the ingredients. One study investigated the effects of silymarin on the pharmacokinetics of irinotecan. Conclusion: The results of this study showed that some of the properties of milk thistle, such as protection and the treatment of liver diseases, treatment of skin disorders, and anticancer effects that have been proven in recent studies are referred to in traditional medicine texts; therefore, it seems that traditional medicine combinations can be useful in modern medical interventions. An early study from finland found that a four-week course of silymarin supplements lowered key liver enzymes in people with subacute disease, suggesting the liver was functioning more normally.
The commission e approved the internal use of crude milk thistle fruit preparations for dyspeptic complaints. Here are 7 science-based benefits of milk thistle. A number of companies on the internet claim that milk thistle can help to detoxify and protect your liver. The active ingredient in milk thistle is silymarin. The active ingredient in milk thistle can help to reduce inflammation. Mucositis scores (World health organization, national cancer institute common toxicity criteria) were significantly lower in the silymarin group. Summary in animals, milk thistle has been shown to stimulate bone mineralization. In vitro and animal studies suggest potentially beneficial effects with milk thistle in pregnancy.
Summary one study has shown that people taking milk thistle supplements experienced a decrease in the number of acne lesions on their body. Most important of all, these medicines should be given only by physicians (I. Some people are advised to be cautious when taking milk thistle. Sjw is a flowering herb that may have antidepressant properties; it is commonly used in europe, particularly in germany. Many people also use cam therapies that may help boost your immune function, and help make you feel stronger and less tired while taking conventional medications, including herbal and vitamin supplements, homeopathy, acupuncture, and massage therapy. The active ingredient in milk thistle, silymarin, acts as an antioxidant by reducing free radical production. The products on this website are herbal dietary supplements and contain no pharmaceuticals or synthetic chemical ingredients. In a clinical trial of patients with prostate cancer and rising prostate-specific antigen (Psa) levels following radical prostatectomy or radiotherapy, a dietary supplement containing silymarin, soy, isoflavones, lycopene, and antioxidants delayed psa progression; however, because the product contained several ingredients, outcomes cannot be attributed to any single ingredient.
In an investigation of the effect of a variety of flavonoids on the formation of dna damage, silymarin did not induce dna damage in colon (Caco-2) cells, hepatoma (Hepg2) cells, and human lymphocytes. Share on pinterest milk thistle tea may help to prevent bone loss caused by a lack of estrogen. Neopterin, a marker of cellular immune system activation, and tnf-alpha were decreased in both groups after silymarin therapy, whereas production of interferon-gamma and il-4 were increased. Milk thistle extract by herb pharm is prepared with a unique double-extraction process that maximizes it’s broad-spectrum silymarin content. Naturopathy also utilizes evidence-based medicine and modern scientific research to combine conventional and complementary and alternative medicine to treat the diseases. Powdered milk thistle can be made into a tea. Ultimate herbal health products comply with the dietary supplement laws in new zealand. The british herbalist culpepper reported milk thistle to be effective for relieving obstructions of the liver.
Purposemilk thistle, an herbal compound, is the dietary supplement taken most frequently by patients with chronic liver disease. One source suggests daily doses of 12 to 15 g of dry fruits for dyspepsia and disorders of the biliary system, while an extract containing 200 to 400 mg/day of silymarin is considered effective in various liver disorders.