Source Naturals, Alpha Lipoic Acid, 50 mg, 100 Tablets

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Product name: Source Naturals, Alpha Lipoic Acid, 50 mg, 100 Tablets
Quantity: 100 Count, 0.05 kg, 4.6 x 4.6 x 8.4 cm
Categories: Source Naturals, Supplements, Antioxidants, Alpha Lipoic Acid

Dietary Supplement, Antioxidant Protection, Alpha-lipoic acid is a powerful fat-and water-soluble antioxidant. It directly recycles vitamin C and indirectly recycles vitamin E, providing additional antioxidant protection. It is also an important component in the energy production process in the cells. Alpha-lipoic acid may support the normal insulin response and healthy blood sugar levels already within the normal range.

In fact, lipoic acid has been shown to increase glucose uptake by plasma membranes through recruitment of glucose transporter-4, a mechanism shared with insulin; moreover, dihydrolipoic acid scavenges superoxide and peroxyl radicals, and facilitates vitamin-e recycling. Alpha-lipoic acid should not be used in place of medication prescribed for you by your doctor. As an antioxidant, it works throughout the body to neutralize harmful free radicals in a variety of ways. Lipoic acid (La) is a natural antioxidant which is believed to have a beneficial effect on oxidative stress parameters in relation to diseases of the cardiovascular system. Feeding acetyl-l-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. My treatments include spinal decompression, daily decompression stretches, and a few other supplements for nerve regeneration and nourishment. Previous studies have supported positive roles of antioxidant supplements on weight-loss. Alpha-lipoic acid is an organic compound found in all human cells. Although lipoic acid does not chelate the ferric ion, 97 it has been shown to form a complex with the ferrous ion.

Source Naturals, Alpha Lipoic Acid, 50 mg, 100 Tablets: Alpha Lipoic Acid, Antioxidants, Supplements

It is believed by some that alpha-lipoic acid, given in large enough doses, can counter this stress by exerting potent antioxidant activity. Ala also has antioxidant properties and thus is important for controlling free radicals. The effect of lipoic acid on eae has been evaluated in many studies. Alpha lipoic acid is an enzyme that, when applied topically on skin, is a good antioxidant. I read online that alpha lipoic acid helps stabilize your blood sugar and i noticed that i felt some energy with it during the day and my appetite was lessened. The pharmacology of the antioxidant lipoic acid. In cells, la is reduced to dihydrolipoic acid, which is generally regarded as the more bioactive form of la and the form responsible for most of the antioxidant effects and for lowering the redox activities of unbound iron and copper. Supplements that claim to contain only r-lipoic acid are usually more expensive, and information regarding their purity is not publicly available. What are the suggested uses for alpha lipoic acid? In this sense, the chronic hyperglycemia that is present in t2dm activates several unusual metabolic pathways in organisms, such as the sorbitol pathway (Or that of aldose reductase), nonenzymatic protein glycosylation, glucose autooxidation, modification of protein kinase c activity, pseudohypoxia, lipoprotein-altered metabolism, and cytokine-associated alteration. Alpha lipoic acid can lower the level of vitamin b1 (Thiamine) in the body. However, only a handful of studies have investigated alpha-lipoic acid and memory loss-related disorders.

Humans only produce alpha-lipoic acid in small amounts. While this approach would be impractical in clinical practice, it does hint at the potential benefit of alpha-lipoic acid in preventing the onset of type 2 diabetes. Alpha-lipoic acid (Ala) as a supplementation for weight loss: Results from a meta-analysis of randomized controlled trials. La supplementation significantly reduced tbars, aopp and improved tas levels in healthy subjects, while there were no significant differences in patients group. It is important to discuss safety issues with your physician before taking any new supplement or medication. In this chapter, evidence is provided to support the proposal that the thiol antioxidant lipoic acid (La) may fulfill this therapeutic need. Cytosolic and mitochondrial systems for nadh- and nadph-dependent reduction of alpha-lipoic acid. I found out about alpha lipoic acid, ala, for a book on home cures by johnny bowden which i bought for my kindle fire. Lipoic acid occurs naturally in food covalently bound to protein, whereas supplements contain unbound (Free) lipoic acid. Neuroprotection by the metabolic antioxidant alpha-linoic acis. Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement. Other antioxidants work only in water (Such as vitamin c) or fatty tissues (Such as vitamin e).

Lipoic acid is also a powerful antioxidant. It is essential for people considering taking ala supplements to talk to their doctor to see if it is right for them. Alpha-lipoic acid may benefit people with diabetes or pre-diabetic conditions by helping to maintain healthy blood sugar levels. However, there is little research exploring the long-term safety of alpha-lipoic acid, including at what point the supplement may become toxic. If you are being treated with any of the following medications, you should not use alpha-lipoic acid without first talking to your health care provider. That said, supplements can pack up to 1,000 times more alpha-lipoic acid than food sources. It has long been presumed that alpha-lipoic acid can aid in the control of glucose by increasing the speed in which the blood sugar is metabolized. Because of the potential for side effects and interactions with medications, you should take dietary supplements only under the supervision of a health care provider. Researchers believe alpha-lipoic acid helps improve insulin sensitivity. Read as much independent research as you can when you take any supplement. Researchers estimate that the addition of antioxidants by supplementation could decrease the risk of heart attack by 20-30%!

Packer and colleagues suggest that ala may also have much broader use in treating other diseases and may have general health benefits when taken as a daily supplement like other antioxidants. It also functions as an antioxidant, meaning that it helps to prevent cell damage from free radicals. More research is needed before alpha-lipoic acid can be recommended for treatment. Suggested use: As a dietary supplement, adults take one Or more tablets per day as directed by your healthcare provider. Case reports or cases series, and the studies did not achieve the minimum quality assessment score, those receiving any non-steroidal anti-inflammatory drug or ala supplements within the last month were also excluded from the study. Studies have shown that this antioxidant may help improve memory performance when taken along with l-carnitine. The use of lipoic acid is currently approved for the treatment of diabetic neuropathy in germany. Are there any known side effects of alpha lipoic acid? Alpha-lipoic acid in liver metabolism and disease. In addition, lipoic acid supplementation did not reduce the severity of multiple sclerosis symptoms, as assessed by the expanded disability status scale (Edss) scoring system (98, 99).

Source Naturals Alpha Lipoic Acid

The reduced form of la, dihydrolipoic acid (Dhla), is the active compound responsible for most of these beneficial effects. A randomized, placebo-controlled study in 52 subjects (Mean age, 30 years) with relapsing-remitting multiple sclerosis found an increase in total antioxidant capacity in blood with lipoic acid supplementation (1,200 Mg/day for 12 weeks) yet not in the activity of specific antioxidant enzymes (Superoxide dismutase and glutathione peroxidase). Other ingredients:Sorbitol, natural tropical punch flavoring, alpha lipoic acid, citric acid, natural menthol flavoring, silicon dioxide, sucralose, plant cellulose capsule. This universal solubility results in ala being able to deliver it’s powerful protective benefits throughout the entire body and why it is often referred to as the universal antioxidant. The synthesis of lipoic acid has been characterized in detail in the yeast saccharomyces cerevisiae, but not all genes involved in the process have been identified in humans. Alpha-lipoic acid is generally considered safe when taken as an oral supplement or used as a topical ointment. I am just learning about berberine and it has so many health benefits i am glad i found this supplement.

Called the universal antioxidant because it is both fat-soluble and water-soluble, lipoic acid can destroy more free radicals than most antioxidants. Alpha-lipoic acid is both water- and fat-soluble, which allows it to work in every cell or tissue in the body. Natural ala, referred to as r-lipoic acid or (R)-ala, is found in exceedingly miniscule amounts in animal and plant tissues, tightly bound to mitochondrial complexes. Alpha lipoic acid is a powerful antioxidant and, as such, is a strong protection against disease. Alpha-lipoic acid is an antioxidant also known as acetate replacing factor, ala, biletan, lipoicin, thioctan, and many other names. Honestly, what is not to like about this alpha lipoic acid? Packer, ala is more potent than vitamins c and e, and coq10, and may, in fact, be the most important antioxidant ever discovered. This systematic review and meta-analysis of randomized controlled trials (Rcts) was conducted to determine the effect of alpha-lipoic acid (Ala) supplementation on the inflammatory markers among patients with metabolic syndrome (Mets) and related disorders. Ala is also able to regenerate the reduced forms of other antioxidants, such as vitamins c and e. Among the beneficial health effects of taking ala supplements, it has been observed that the administration of ala is capable of promoting the synthesis of nitric oxide.

Because both alpha-lipoic acid and dihydrolipoic acid are antioxidants, their combined actions give them greater antioxidant potency than any other natural antioxidant now known. Lipoic acid has been found to increase glutathione concentrations in cultured cells and in the tissues of aged animals fed lipoic acid (29, 30). Alpha lipoic acid is found naturally in foods such as spinach, broccoli, tomatoes, liver, heart and animal muscle tissue. Plasma kinetics, metabolism, and urinary excretion of alpha-lipoic acid following oral administration in healthy volunteers. I definitely recommend this berberine supplement. The chemical structure of biotin is similar to that of lipoic acid, and there is some evidence that high concentrations of lipoic acid can compete with biotin for transport across cell membranes (120, 121). Foodpharmacy Blog and nine which passed testing in our voluntary quality certification program, as well as information about three supplements similar to one that passed testing. Alpha lipoic acid has so many uses, it is like magic in a bottle.

I did have the side effect of having a strange smell to my urine, but it was only a couple of times after taking the supplement.