Product name: Starwest Botanicals, Milk Thistle Seed Whole, Organic, 1 lb (453.6 g)
Quantity: 1 lb, 0.54 kg, 22.1 x 17 x 2.3 cm
Categories: Starwest Botanicals, Herbs, Homeopathy, Milk Thistle Silymarin, Kosher, Certified Organic by QAI, USDA Organic
Kosher, Kosher Certified by Kosher Certification Services, Certified Organic by QAI, USDA Organic, Origin: Croatia, Milk Thistle Seeds also known by their scientific name, Silybum marianum, are truly a one of a kind herb. Milk Thistle Seed is world renowned for centuries because of a natural compound called silymarin found in it, Silybum marianum or Milk Thistle Seeds are native to the Mediterranean region and grow wild throughout the countryside’s of Europe, North America and Australia, Milk Thistle Seeds Powdercontains a flavonoid complex known as silymarin, which is the component responsible for all of the herb’s purported medical benefits.
The major constituents of silymarin are the three diastereomeric pairs, silybins a and b (Also called silibinin), isosilybins a and b, silychristin, isosilychristin, and silydianin. A well known hepatic antioxidant, silymarin, from the milk thistle (Silybum marianum), inhibits liver damage by scavenging free radicals among other mechanisms. Some experts suggest that under the theory and method of modern western medicine pharmacology, the mechanism and the curative effect of traditional chinese medicine are often difficult to illustrate. Pregnant and breastfeeding women should never take herbs or supplements unless expressly approved by their physicians. The oldest reported use of milk thistle was from the ancient greeks and romans, who used this plant as a treatment for liver ailments and snake bites. This information relates to an herbal, vitamin, mineral or other dietary supplement. In an investigation of the effect of a variety of flavonoids on the formation of dna damage, silymarin did not induce dna damage in colon (Caco-2) cells, hepatoma (Hepg2) cells, and human lymphocytes.
Starwest Botanicals, Milk Thistle Seed Whole, Organic, 1 lb (453.6 g): Milk Thistle Silymarin, Homeopathy, Herbs
In this review, we select and discuss blood glucose-lowering medicinal herbs that have the ability to modulate one or more of the pathways that regulate insulin resistance, -cell function, glp-1 homeostasis, and glucose (Re)absorption. According to research conducted by the original manufacturer and primary researcher of milk thistle extract, madaus ag of cologne, germany, this level of concentration of silymarin is required to survive degradation by gastric fluids and in order to enter into the bloodstream via the intestinal wall. If you are taking any medications or have any serious health condition please consult with a healthcare professional before using ultimate herbal health products. A preparation consisting of 150 ml of boiling water poured over 3,5 g of crushed milk thistle seed, steeped for 10 to 15 minutes, and given 3 to 4 times daily 30 minutes before meals has been suggested for digestive disorders. However, when silymarin was combined with these agents, serum indices and hepatic markers were reduced. We use a triple percolation process which creates, without heat, a more concentrated extract which contains the full-spectrum of milk thistle’s silymarin flavonoids silybin, silydianin and amp; silychristin. In traditional chinese medicine, milk thistle is referred to as da ji, while the seeds are called shui fei ji. Intense research activity has been dedicated to the identification of natural products from traditional medicine that regulate abca1 expression.
The hepatoprotectant effect of milk thistle fractions (Silymarin) is documented in other studies: These compounds can produce both a protective and curative effect on liver damage resulting from the highly toxic compounds phalloidin and alpha-amanitin (From the deathcap mushroom, a. While there are numerous other constituents with known pharmacological activity, such as quercetin, the extract of milk thistle achenes is standardized for quality control on the content of silymarin, e. The name milk thistle comes from the story of the virgin mary who was sheltering under the thorny leaves of the milk thistle while nursing baby jesus. It must contain not less than 2% of silymarin, calculated as silybin, as determined by a usp spectrophotometric assay method. Licorice, the common name for the plants that comprise the genus glycyrrhiza, is utilized as herbal medicine for a wide range of diseases. They suggest that a substance in milk thistle (Silymarin) can protect the liver from damage caused by viruses, toxins, alcohol, and certain drugs such as acetaminophen (Tylenol). 70% Of the extract weight such that a 200 mg tablet contains 140 mg of silymarin, or 200 – 400 mg per daily dose. Mucositis scores (World health organization, national cancer institute common toxicity criteria) were significantly lower in the silymarin group. Laboratory data suggest that silymarin and silybin protect the liver from damage induced by toxic chemicals.
Studies have found that silymarin reduces transcription of markers of tumor promotion and activity, inhibits transcription of tumor promoters, interferes with cell signaling, inhibits inflammatory actions, and modulates cell-cycle regulation. Because it acts on the liver, milk thistle can theoretically interact with several medications that are processed through the liver. Other substances in milk thistle have not been extensively studied. More studies are needed before it can be determined how silymarin might be used to support people undergoing cancer treatment. Because of the relative convenience, safety and efficacy, natural medicine is now increasing worldwide. This article explores 10 potential milk thistle benefits and examines whether there is any scientific evidence to support it’s use. Rare cases of milk thistle producing a laxative effect have been reported.
The use of herbs is a time-honored approach to strengthening the body and treating disease. In a double-blind, placebo-controlled trial, 50 children who were undergoing treatment for acute lymphoblastic leukemia, and who had chemotherapy-related hepatotoxicity, were randomly assigned to receive silymarin or placebo for a 4-week period. Collectively, these findings suggest that mate and probably it’s active compounds act as an antidiabetic medicine through augmentation of glp-1 production. In the eclectic medicine movement (19Th to 20th century), milk thistle was used to treat varicose veins, menstrual difficulty, and congestion in the liver, spleen, and kidneys. Naturopathic doctors must follow the principles which underlie and are determined by the practice of natural medicine. A formula composed of two or more drugs has been demonstrated as more beneficial for disease treatment, but the selection of individual herbs in the formula must be strictly guided by the principles underlying chinese herbal medicine. Ultimate herbal health limited is a member of natural products new zealand. The median time to toxicity was prolonged significantly with the silymarin-based cream (45 Vs.
Starwest Botanicals Milk Thistle Silymarin
Human research studies have shown that it is more effective to administer this herb in three or four small portions over the day than in one large daily dose. However, there are currently no human studies examining the effects of milk thistle in people with alzheimer’s or other neurological conditions like dementia and parkinson’s. The seed-like fruits (Achenes) of milk thistle are the medicinal parts of the plant. A few trials have looked at milk thistle for people with cancer. Naturopathic doctors are licensed in many areas of the world and regulated partly by law in these areas, which is quite different from various other forms of complementary and alternative medicine. It also looks at how to use milk thistle and whether there are any risks to consider. Therefore, when administrating naturopathic protocols to patients for the treatment of liver diseases, we should try our best to prevent and avoid as much as possible the negative impact of these medicines. Pregnant or breastfeeding women should not use milk thistle or licorice. Scientists think this creates a detoxifying effect, which is why it is milk thistle may be beneficial for liver problems.
In a nonrandomized observational trial of 101 women with breast cancer who had undergone breast-conserving surgery followed by radiation therapy with 50,4 gy plus a boost of 9 gy to 16 gy, a silymarin-based cream (Leviaderm) was tested in 51 women compared with panthenol-containing cream, the standard of care (Soc), which was given interventionally if local skin lesions occurred and administered to 50 women. In ovariectomized rats, treatment for 12 weeks with silymarin prevented bone loss, either through increasing formation via an effect on calcium, phosphorus, osteocalcin, and parathyroid hormone, or through direct action with estrogen receptor-beta. However, studies are mixed as to whether milk thistle improves liver function tests or quality of life for people with chronic active hepatitis b or c. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. Health canada has registered two milk thistle products in the herbs and natural products category, a liquid preparation and a capsule, and four milk thistle products in the homeopathic category, including liquid, pellet, globule, granule, and tablet formulations. Nature is an extraordinary source of antidiabetic medicines. Herbal and complementary and alternative medicine therapies for liver disease. Natural medicine is a system of therapy that administrates natural agents and their derivatives to treat human diseases. A dose of 140 mg of silymarin 3 times daily has been suggested for hepatic cirrhosis.
Currently, understanding of the mechanisms through which herbal therapies mediate t2d is evolving, and they are generally being viewed as modulating of multiple metabolic pathways. A case report from australia described a reaction to a milk thistle extract that included intermittent episodes of sweating, abdominal cramping, nausea, vomiting, diarrhea, and weakness. Specifically, silymarin has been shown to stimulate the glutathione s-transferase pathway and alter the intracellular concentration of glutathione (A potent antioxidant). Toxic effects of silymarin have not been noted clinically at a dosage of 1,200 mg/day; however, mild allergies were reported with dosages greater than 1,500 mg/day. Milk thistle is one of very few traditionally used herbs that has been widely accepted by conventional science to have significant medicinal value. In this review, the antidiabetic potential of the selected glucose-lowering herbs and their different mechanisms of action were summarized and discussed. An adverse reaction to the herbal medication milk thistle (Silybum marianum). G, alcohol and certain pharmaceutical drugs), researchers attempted to determine whether milk thistle would be helpful for patients being administered psychotropic drugs. These studies have also seen that milk thistle may be able to reduce the number of amyloid plaques in the brains of animals with alzheimer’s disease (18, 19, 20). Pharmacokinetics of silybin in bile following administration of silipide and silymarin in cholecystectomy patients.
The tincture should be bright yellow, indicating the presence of the resinous fraction which contains the silymarin. However, at least two articles in major journals have suggested that silymarin or it’s congeners may inhibit hcv. Although milk thistle has not significantly altered the course of chronic liver disease, it has reduced liver enzyme levels and demonstrated anti-inflammatory and t cell-modulating effects. Given this phytomedicine’s well established safety and it’s reasonable documentation of efficacy, future clinical use of milk thistle extract should be explored as an adjunct therapy in chemotherapy to help offset the effects of powerful and potentially hepatotoxic conventional drugs. Milk thistle preparations are usually standardized to a concentration of 70 to 80% of three flavonolignans (Silibinin, silychristin, and silydianin), collectively known as silymarin. Complementary and alternative medicine in chronic liver disease. The authors concluded that the recommended doses of milk thistle are too low to affect activity of cyp3a4 or ugt1a1 enzyme pathways. Summary initial test-tube and animal studies have shown that milk thistle has some promising characteristics that could make it useful for protecting brain function. Licorice root (Glycyrrhiza glabra): Licorice root has been used in both eastern and western medicine to treat a variety of illnesses, including liver disease.
Silybin and silymarin have been studied in the treatment of aging skin and rosacea, as well as in skin cancer prevention. Of the 170 patients, 87 received 420 mg of silymarin daily, compared with 83 placebo patients. The aim of natural medicine is to treat the cause of a disease rather than just the symptoms, like allopathic medicine often does. The standard dosage of milk thistle extract is based on a silymarin content of around 80 percent; most supplements contain anywhere from 50-500 milligrams (175 Mg is typical).