Product name: Superior Source, Extra Strength Vitamin D3, 1,000 IU, 100 MicroLingual Instant Dissolve Tablets
Quantity: 100 Count, 0.02 kg, 4.3 x 4.3 x 8.9 cm
Categories: Superior Source, Supplements, Vitamins, Vitamin D, D3 Cholecalciferol, Non Gmo
Instant Dissolve Tablets, Dietary Supplement, GMO Free, Our Instant Dissolve MicroLingual Tablets may be small but they are full potency! Typical tablets and capsules need to be swallowed and are inefficiently absorbed in the digestive system. MicroLingual tablets dissolve immediately under the tongue heading straight into the body. Our proprietary hydrodrying process results in fewer inactive binders and fillers and a higher ratio of nutritional ingredients—hence the small size. They efficiently provide your body with the nutrients you need right now, “Less is More”, Simplicity Purity Efficiency, No pills to swallow, Place on or under the tongue, Dissolves on contact, GMO and preservative free.
Association between inflammatory bowel disease and vitamin d deficiency: A systematic review and meta-analysis. The degree of vitamin d deficiency is determined according to the 25(Oh)d levels in the blood. However, according to a recent meta-analysis, this difference between d 2 and d 3 is lost with daily administration, implying differences in the catabolism of these two vitamin d forms. Similarly, the results of the studies that evaluate the correlation between vitamin d metabolites and the gh peak after stimulus testing in ghd patients are conflicting. If using any pharmaceuticals or drugs given to you by a doctor or received with a prescription, you must consult with the doctor in question or an equally qualified health care professional prior to using any nutritional supplementation. In fortified foods and supplements, vitamin d is also available in two forms, vitamins d2 (Ergocalciferol) and d3 (Cholecalciferol), that differ in their side-chain structure only. In the epidermal strata of the skin, vitamin d production is greatest in the stratum basale (Colored red in the illustration) and stratum spinosum (Colored light brown). In recent years, research has associated low blood levels of the vitamin with higher risks of everything from heart disease, diabetes, and cancer to mood disorders and dementia. Vitamin d is a lipid-soluble vitamin with a steroidal structure that exerts numerous essential cellular and molecular functions. It’s also recommended to take vitamin d for better mental health.
Superior Source, Extra Strength Vitamin D3, 1,000 IU, 100 MicroLingual Instant Dissolve Tablets: D3 Cholecalciferol, Vitamin D, Vitamins, Supplements
14, 70- 72 The effectiveness and clinical benefits of vitamin d are significantly reduced when magnesium homeostasis in the body is not maintained. The major natural source of the vitamin is synthesis of cholecalciferol in the lower layers of skin epidermis through a chemical reaction that is dependent on sun exposure (Specifically uvb radiation). However, it is important to follow dosing instructions closely and to avoid taking multiple products that contain vitamin d (Eg, multivitamin and vitamin d). More recently, a number of trials in healthy children tested vitamin d doses at the upper levels set by the iom and with the goal of increasing serum concentrations above 30 ng/ml. A united states institute of medicine (Iom) report states: Outcomes related to cancer, cardiovascular disease and hypertension, and diabetes and metabolic syndrome, falls and physical performance, immune functioning and autoimmune disorders, infections, neuropsychological functioning, and preeclampsia could not be linked reliably with calcium or vitamin d intake and were often conflicting. Vitamin d is a fat-soluble vitamin important for bone health. Or a low vitamin d blood level could be a consequence of obesity; the vitamin is soluble in fat, so it can become sequestered inside adipose tissue.
About four million australians now suffer from a vitamin d deficiency, according to the latest abs data. The vitamin d council recommends staying in the sun for half the time it takes your skin to turn pink or red. Severe vitamin d deficiency in children causes rickets, a softening and weakening of bones, which is a rare disease in the developed world. When the manufacturing method for ergocalciferol was created, binding studies of the vitamin d receptor in rats showed equipotency between ergocalciferol and cholecalciferol. The aforementioned meta-analysis of observational studies Indicates that with the 4,7 ng/ml increase in 25-hydroxyvitamin d level obtained in the whi trial, a 7% decrease in the risk of colorectal cancer could have been expected. And some pills contain the less-accessible form of vitamin d produced by plants, called d2, not the version made by the human body, called d3, nothing about vitamin d is simple. Some studies on mice with a targeted deletion of vdr have allowed the scientific community to better understand some of the consequences of vitamin d deficiencies on the growth plate; in particular, it seems that a reduction of 1,25(Oh) 2d causes a reduction of the apoptosis of hypertrophic chondrocytes, cartilage calcification and the number and activity of chondroclasts/osteoclasts. In this capacity, vitamin d functions as a part of a control system that operates to maintain constancy of the calcium ion concentrations in the extracellular fluid against the demands of obligatory excretory losses and skeletal mineralization.
Seasonal changes in human plasma levels of 25-hydroxyvitamin d. Cholecalciferol supplementation alters gut function and improves digestibility in an underground inhabitant, the naked mole rat (Heterocephalus glaber), when fed on a carrot diet. In fact, recent studies have also shown that vitamin d, gh and igf-1 have an impact on bone and cartilage as well as they act on epiphyseal chondrocytes. Lesson of the week: Florid rickets associated with prolonged breast feeding without vitamin d supplementation. The biology and pathology of vitamin d control in bone. Vitamin d2 treatment for vitamin d deficiency and insufficiency for up to 6 years. Vitamin d deficiency remains the main cause of rickets among young infants in most countries, because breast milk is low in vitamin d and social customs and climatic conditions can prevent adequate sun exposure. About 5,000 people from the general population of new zealand were randomly assigned to receive the vitamin d boost or a placebo. You should not take more than 4,000 iu a day of vitamin d3 unless your doctor tells you otherwise. 88 Studies have suggested that magnesium could influence pth synthesis and determine the number of vitamin d receptors; therefore, a deficiency in magnesium levels may lead to diminished synthesis and secretion of pth and a reduced number of available vitamin d receptors in the target cells.
Low blood calcifediol (25-Hydroxy-vitamin d) can result from avoiding the sun. Chemically, the various forms of vitamin d are secosteroids, i. If you have a well-balanced diet, which regularly includes good sources of vitamin d, you may not need a supplement at all. (Meaning, the group receiving vitamin d supplementation did not appear to do better). In other words, much of the data does not clearly support the idea that vitamin d supplementation in a patient with low vitamin d levels reduces the risk of these diseases. I do wish you would consider doing some writing about vitamin b12 and the need for testing individuals that have lost the ability to fully utilize or uptake b12 from foods rich in b12, we have about seven members (Age 66 to 87) in our diabetes support group that need to take a vitamin b12 supplement on a daily basis. Special considerations for vitamin d in the south asian population in the uk. All of these conditions have been linked with vitamin d levels in at least one study. Only a few foods are a good source of vitamin d. What is less clear are the exact doses necessary to maintain vitamin d health or repair inadequacies, and what the evidence is upon which these official and anecdotal recommendations are made. In addition, taking a supplement that contains too much vitamin d can be toxic in rare cases. Although the research is still hazy, some people will benefit from taking vitamin d supplements, along with sufficient calcium intake, to promote their bone health.
Superior Source D3 Cholecalciferol
Adequate intake of vitamin d has shown to diminish the risk of some of the skeletal as well as nonskeletal disorders. Yet the endocrine society recommends a greater amount of supplementation for children at risk for vitamin d deficiency or low bone density mass: From 400 to 1,000 iu for children 1 year and younger, and 600-1,000 iu for all older children, adolescents, and adults. Another study of people living in hawaii found that many had lower vitamin d levels than one might expect. Does vitamin d supplementation alleviate chronic nonspecific musculoskeletal pain? A single, large dose of vitamin d given at timed intervals may be an alternative strategy. I liked the look of the bottle and the idea of vitamin k being combined with vitamin d3, my usual vitamin d3 was always an oil-based substance contained in gelatin sometimes veggie form so i must admit i was surprised by this powder substitute. Anything less than 12,5 nmol/l is considered to be a severe vitamin d deficiency. The main symptoms of vitamin d overdose which are those of hypercalcemia including anorexia, nausea, and vomiting. Serum calcium concentrations plotted against 25ohd concentrations (Left) and vitamin d intake (Right) in infants and children with vitamin d intoxication.
I went away for a short holiday and forgot to take with me my 400microgram vitamin d3 supplement tablets. Weight loss – though hypothesized that vitamin d supplementation may be an effective treatment for obesity apart from calorie restriction, one systematic review found no association of supplementation with body weight or fat mass. Urine deoxypyridinoline levels decreased by about 41% in the magnesium-supplemented group and by 5% in the control group (Without supplements). The national academy of medicine advises a vitamin d intake of 600 to 800 international units per day to achieve blood levels of 20 nanograms/milliliter of the nutrient (One of the lower recommended thresholds). In other words, if you go get your sunlight in the early morning or late afternoon, when the sun is lower in the sky, the sunlight is much less effective in prompting vitamin d production. We performed a systematic search of published randomized trials on vitamin d supplementation in subjects over 50 yr old, whatever the endpoint of interest. 1,13 One expert recommends sensible sun exposure as an important adjuvant to vitamin d supplementation; such exposure, from either sunlight or ultraviolet radiation (Tanning beds), would involve 5-30 minutes to arms and legs twice weekly between the hours of 10 am and 3 pm while wearing sunscreen on the face. This results in inadequate amounts of active vitamin d. Geographical location: People who live in northern latitudes or areas of high pollution, work night shifts, or are homebound should aim to consume vitamin d from food sources whenever possible.
Ideal form of vitamin d supports maintenance of healthy bones and teeth, cellular function and proper functioning of the immune and nervous systems. Sunlight and vitamin d: Both good for cardiovascular health. The first one, a short-term study of 3 months that involved 113 newborns, showed no case of vitamin d excess and associated hypercalcemia or hypercalciuria. The issue of sun exposure is relevant not only for people with problems absorbing or converting vitamin d; the medical literature contains many references to the relevance of sufficient sun exposure, for all ages, to vitamin d status and various disease states, of course balanced by concerns from the dermatological camp about increased risk of skin cancer. Some studies suggest that vitamin d reduces people’s risk of dying during the study periods, indicating that it may help you live longer (36, 37). Some trials did not report baseline 25-hydroxyvitamin d levels (25, 30), And we took the in-trial level in the control group as surrogate for baseline levels in both control and intervention groups. One study found that age-related declines in kidney function may require older people to ingest more vitamin d3 to maintain the same blood levels as younger people. Effect of race and genetics on vitamin d metabolism, bone and vascular health. Vitamin d supplementation, moderate sun exposure, and control of immune diseases. An ideal way to obtain vitamin d, as few foods contain vitamin d in sufficient quantity to meet daily value levels.
Exposure to the sun is not recommended as a source of vitamin d for infants and children, due to the potential long-term risks of skin cancer. Vitamin d3 (Cholecalciferol) for vitamin d deficiency: I have been struggling with arthritis-like pain for months. We found two main areas of interest: The vitamin d deficiency status in patients affected by gh deficit (Ghd) and the relationship between serum vitamin d metabolites and igf-1, although limited by some bias, from the analysis of the studies presented in the scientific literature, it is possible to hypothesize a greater frequency of hypovitaminosis d in the subjects affected by ghd, a reduced possibility of it’s correction with only substitution treatment with recombinant growth hormone (Rgh) and an improvement of igf-1 levels after supplementation treatment with vitamin d. Osteomalacia is usually present when 25-hydroxyvitamin d levels are less than about 10 ng/ml. Association between maternal serum 25-hydroxyvitamin d level and pregnancy and neonatal outcomes: Systematic review and meta-analysis of observational studies.