Product name: Thorne Research, Phosphatidyl Choline, 60 Gelcaps
Quantity: 60 Count, 0.16 kg, 6.6 x 6.6 x 12.7 cm
Categories: Thorne Research, Supplements, Phospholipids, Phosphatidylcholine, Gluten Free
Dietary Supplement, Foundational, Liver/Detox, Gluten Free, Phosphatidyl Choline (PC) has been shown in numerous studies to protect liver cells from toxin damage. PC also exhibits the potential to decrease dietary cholesterol absorption, Phosphatidylcholine is a major component of the membranes of the liver cells (hepatocytes). As such, it provides significant protection for the liver, probably because good liver health requires the ongoing replacement of old cell membranes with healthy new ones. Phosphatidylcholine has been shown in numerous studies to protect liver cells from damage from a variety of toxins, including ethanol, carbon tetrachloride, trichloroethylene (used in dry cleaning and as a degreasing solvent), and mushroom toxins. Phosphatidylcholine is an important component of the lipids that circulate in the bloodstream, and is a major constituent of bile, which is necessary to metabolize fats. Phosphatidylcholine also has the potential to decrease the absorption of dietary cholesterol, which helps maintain a normal cholesterol level, The findings from eight double-blind clinical trials and numerous other reports that have studied phosphatidylcholine indicate that it supports faster rebuilding of liver tissue and accelerated restoration of overall wellbeing.
This means that the supplementation with mpls during diseases causing cachexia could be recommended as supportive therapy to achieve stabilisation of the cachectic syndrome and therefore improve therapeutic results. Since lecithin is in everyone and not just provided by supplements, we need to know if people suffering from heart conditions have faulty lecithin metabolism. Supplementation with pc and menaquinone-4 was also tested in rats, showing a clear suppression of nodule formation (Precursors of hepatic cancer) and preneoplastic liver lesions in supplemented rats, compared to the control group. In general, most supplements containing phosphatidylserine complex often include 2 or more phosphatidyl compounds. Buchman al, awal m, jenden d, roch m, kang s-h: The effect of lecithin supplementation on plasma choline concentrations during a marathon. Eliminate dietary (Or supplemental if your diet is deficient) choline at your peril. Polyunsaturated phospholipids increase the hypolipidemic effect of lovastatin. Additionally, the phospholipids that compose the liposome shell feed the cell membranes.
Thorne Research, Phosphatidyl Choline, 60 Gelcaps: Phosphatidylcholine, Phospholipids, Supplements
In various sports activities pc supplementation has enhanced performance where exercise has depleted choline concentrations. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect. Phosphatidylserine has been demonstrated to be an effective supplement for combating exercise-induced stress and preventing the physiological deterioration that accompanies too much exercise (I. As the name suggests, this is a phospholipid (Fatty acid group) attached to a choline molecule and the combination is found throughout the body, but often supplemented with soy lecithin. People should research the supplements and the brand names before taking them. The supplement industry had to lobby the government to avoid a take-over by big pharma and the medical community for a good reason. Phosphatidylserine complex article is a comparative review between 2 phospholipid sources that are taken in supplement form to promote brain health. Lactic acid values with pc supplementation were lower in 8 out of 10 runners and time to recover was 12% shorter. It was concluded that choline was not depleted in either condition nor did choline supplementation delay fatigue. Short term oral supplementation with soy-derived ps (S-ps) has been reported to attenuate circulating cortisol concentrations, improve perceived well-being, and reduce perceived muscle soreness after exercise.
However, due to the risk of potential transfer of infectious diseases such as bovine spongiform encephalopathy (Or mad cow disease ), soy-derived ps supplements have been used as an alternative. Previous studies have also documented the effects of prenatal choline supplementation on developing brains. In another mouse study, prenatal choline supplementation helped babies born with down’s syndrome learn better and even protected the mice’s brains from alzheimer’s later in life. Recent studies with soya ps supplementation showed stress lowering effects and improvements on concentration parameters in young and healthy subjects. All the above mentioned effects were attributed to the whole pl, since the effects were not observed when supplementing ffa or the head group alone. Pc is an important supplement for liver health and has shown significant benefits to patients with hepatitis b and c. Eicosanoid messenger molecules, generated from 20-carbon fatty acids associated with membrane phospholipids, are among the major factors ensuring vessel wall homeostasis. Quickly and easy look up evidence on over 400 supplements across over 500 different health goals, outcomes, conditions, and more. If someone has high cholesterol or a history of heart disease, they should discuss the supplement with their doctor.
Ps supplementation was reported to reduce muscle damage in trained runners compared to placebo (See figure 9). Membrane phospholipids as well as their fatty acid profile are altered in tumor cells. Like the other products on this website, the liposomal structures in our supplements provide more efficient and effective delivery to the blood stream. Due to the potential transfer of infectious disease, this supplement is now considered unsuitable. Liposomal supplements contain a nutritional delivery system with rapid uptake and effective delivery into the cells. Spector sa, jackman mr, sabounjian la, sakkas c, landers dm, willis w: Effect of choline supplementation on fatigue in trained cyclists. More recently, short term oral supplementation (750 Mg per day of s-ps for 10 days) has been demonstrated to improve exercise capacity during high intensity cycling and tended to increase performance during intermittent running.
It should be noted that the research on lecithin’s effectiveness in treating these conditions is very limited or nonexistent. Were the patients on lecithin supplementation? Although phospholipids can be found in a wide variety of foods such as meat, eggs, and soy, some individuals including vegans and vegetarians may benefit from supplementation. Larger randomized controlled trials are needed to establish whether citicoline supplementation could be included in the medical treatment of glaucoma. When supplemented with pc average plasma choline levels increased during three hours of rest. Yet, a recent meta-analysis of 11 trials indicated that homocysteine lowering using b-vitamin supplementation fails to limit cognitive decline or improve cognitive performance in older adults. Ignorance is not bliss, and the vociferous defense of the supplements industry by people conned into blindly trusting their claims plays into the hands of a corrupt congress and corrupting industry money. For a higher dose version of this supplement in a liquid format, consider our optimal pc liquid. Optimal pc, by seeking health, is a specialty formula using certified non-gmo sunflower lecithin to deliver 5,200 mg of blended phospholipids.
Thorne Research Phosphatidylcholine
Com and it’s editors do not ensure that unforeseen side effects will not occur even at the proper dosages, and thereby does not assume liability for any side effects from supplements or practices hosted under the domain of examine. Chemically speaking, phospholipids are the active component in lecithin. For this reason, oral supplementation of pl carrying n-3 pufas (Which is a special characteristic of pls from marine origin) may play an important role, not only in the elderly, but also during pregnancy and infancy, where dha provision into the brain is essential for neurological development. Bodybio pc is made of pure phospholipids which automatically form liposomes in the body. There are at least three main phospholipids present in your cells and all of them are in this product. Why do studies on prenatal supplementation matter to the rest of us? Regarding studies; the same criticisms you assault the supplement industry with, can be applied to pharma lobbyists, and the fda. Soy-ps is commercially available as an oral supplement, with recommended daily doses usually ranging from 100 to 500 mg. Note: When buying supplements, look closely at the number of milligrams in each capsule, and the dosage.
The present review explores the various aspects of phytolipid complexes concerning the phospholipids, vesicles, choice of ingredients, phytolipid complexation, advantages, preparation methods, and their applications. Some doctors suggest pc supplements as part of gallstone treatment, though the supporting research is weak. Independent of supplementation with s-ps (750 Mg per day for 10 days) or placebo, downhill running induced similar increases in circulating ck activities, myoglobin concentrations, interleukin-6 concentrations and hydroperoxide concentrations. Cdp-choline (Citicoline) and choline salts, such as choline chloride and choline bitartrate, are available as supplements. Compared to placebo, cortisol levels were 30% lower (800 Mg s-ps), demonstrating that ps supplementation can lessen the severity of stress responses to exercise. Furthermore, pl supplementation was shown to be effective not only in improving alcohol related liver disease, but also after hepatic damage caused by toxins and virus infections. Our proprietary star-rating system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition.
Com does not assume liability for any actions undertaken after visiting these pages, and does not assume liability if one misuses supplements. 1,000S of dollars in doctors, tests, and er visits later, i removed all folic acid supplements from my diet (Blood work showed i had 25 ul or whatever of folic acid when the normal range was maximum of 5). Liposomes are highly efficient in terms of facilitating antioxidant delivery, and because they are prepared from natural phospholipids, they are biocompatible and nontoxic. This non-gmo, soy-free, gluten-free, dairy-free supplement made in the usa. Marine phospholipids (Mpl), carrying mainly n-3 fas, have been described to reduce inflammatory reactions by the inhibition of prostaglandins of the series-2 (Pge2). But, the conclusion that intake or supplementation of pc directly affects the risk for developing cardiovascular disease can not be drawn from this study. After just 3 weeks of ps supplementation they observed a statistically significant improvement of the physiological loss of cognition. But that never stops them from being haughty over natural supplements and medicine. Although lecithin occurs naturally in many foods, lecithin supplements are typically derived from eggs, soy, or sunflower seeds. In one double-blind study published in brain research, the offspring of pregnant mice fed supplemental choline had better memories, learned faster, and had larger brain cells compared to those fed a normal diet.
Is there really lecithin in your lecithin supplement? By becoming an examine plus member, you will have access to all of the latest nutrition research on over 300 supplements across over 500 different health goals, outcomes, conditions, and more. He has been taking it for 10 years, and in conjunction with diet, exercise, and other supplements his blood work and disease markers regularly come back looking better than mine (38 Years his junior)! It is known that folate is critical for normal embryonic development, and maternal supplementation with folic acid decreases the incidence of neural tube defects (Ntds). But now that choline is showing brain health benefits, it may turn out that both supplements are valuable. As an aside, i have studied in the field of functional nutrition/supplementation for over 40 years. If the benefits of fibrate therapy are indeed mitigated by fibrate-induced betaine deficiency, the use and safety of supplementing patients with betaine would need to be considered. Egg yolk lecithin is a more unlikely source of lecithin in dietary supplements. Prohealth has been offering some of the highest quality supplements in the industry for 32 years.
Results from experimental studies have suggested that pharmacological doses of citicoline (Cdp-choline) could enhance the metabolism of glucose and the biosynthesis of phospholipids and neurotransmitters, while limiting the degradation of phospholipids in neuronal membranes in models of ischemia and neurodegenerative diseases (Reviewed in 62). Furthermore, supplementation with ps has been described to improve cognitive, neuropsychological and daily life performance through raising glucose levels in the brain.