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Best Organic Pine Bark Extract Products

Now Foods, Pycnogenol, 30 mg, 150 Veg Capsules

Now Foods, Pycnogenol, 30 mg, 150 Veg Capsules Review

$26.70

Pine bark extract is used to reduce the risk and severity of heart disease, strokes, high cholesterol, and circulation problems. Research has shown that taking pycnogenol daily for 2 months can prevent or reduce the symptoms of retinal disease caused by diseases such as diabetes and atherosclerosis. No side effects due to supplementation were observed; tolerability was optimal. Pine bark extract is gras, based on data from animal studies and clinical trials; however, few studies evaluate safety as a primary outcome. Confusion previously arose when grape seed extract was marketed as containing pycnogenol. The antioxidant properties of pycnogenol support the maintenance of healthy retinal capillaries and better vision. If you have too many free radicals in your system and not enough antioxidants to counterbalance them, your cells can become damaged through oxidization.


Planetary Herbals, Full Spectrum, Pine Bark Extract, 150 mg, 60 Tablets

Planetary Herbals, Full Spectrum, Pine Bark Extract, 150 mg, 60 Tablets Review

$11.50

Pinus morrisonicola hayata, usually called taiwan five-leaf pine (5Lp), is an endemic species in taiwan and is traditionally used to relieve hypertension symptoms and improve cardiovascular function. Research suggests that taking a standardized extract of maritime pine bark by mouth for 3-12 months improves mental function and memory in adults of all ages. The water-soluble flavonoid extract was developed, trademarked, and patented by horphag research international. Inhibition of cox-1 and cox-2 activity by plasma of human volunteers after ingestion of french maritime pine bark extract (Pycnogenol). Participants were queried about their use of dietary supplements and medications at screening and were asked to report any changes. Taking a standardized extract of maritime pine bark by mouth does not seem to help adhd symptoms in adults. There is absolutely no application of pesticides during the growing of the pine trees or toxic solvents during the manufacture of the french maritime pine bark extract, therefore it does not contain any pesticide or solvents. Early research shows that taking a standardized extract of maritime pine bark can decrease ringing in the ears and overall s…


Now Foods, Pycnogenol, 100 mg, 60 Veg Capsules

Now Foods, Pycnogenol, 100 mg, 60 Veg Capsules Review

$28.10

Confusion previously arose when grape seed extract was marketed as containing pycnogenol. Evidence supports the use of dietary supplements such as fish oil for treating and preventing cvd, but rigorous evidence of efficacy and safety is lacking for most supplements. If you have trouble finding a supplier you trust, many of the active ingredients of pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. One critical point with plant extracts is always the bioavailability of their constituents. In contrast, we evaluated the effects of pine bark extract as a solitary therapy, a design more likely to isolate the effect of pine bark extract. Moreover, pycnogenol reduces serum levels of low-density lipoproteins (Ldl) cholesterol and increases high-density lipoproteins (Hdl) cholesterol. Following our a priori primary analysis plan, the effect of pine bark extract on the primary outcome, 12-week blood pressure change, was examined using a regression model with 12-week blood pressure change as the dependent variable and with baseline blood pressure as a covariate. These observations suggest an advantageous risk-benefit ratio for pyc…


Country Life, Pycnogenol, 100 mg, 30 Veggie Caps

Country Life, Pycnogenol, 100 mg, 30 Veggie Caps Review

$33.10

While tinnitus decreased in both groups, the decrease was more significant in those taking pycnogenol. It is an antioxidant, acts as an anti-inflammatory, selectively binds to collagen and elastin, and aids in the production of endothelial nitric oxide. The primary hypothesis was that pine bark extract would lower blood pressure in a population of overweight and obese participants with baseline prehypertension or hypertension. By becoming an examine plus member, you will have access to all of the latest nutrition research on over 300 supplements across over 500 different health goals, outcomes, conditions, and more. Of the flavonoids tested, good protection in the retina was found at 10(-5) M for epigallocatechin gallate (50%) And at 50 ng/ml for pycnogenol (61%) And catechin (52%). A trial of children with adhd found that pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing dna damage. The extract has been used for anemia, inflammation, and cardiovascular conditions. In rodent studies, pine bark extract showed antioxidant effects and improved insulin resistance and hyperglycemia. The results demonstrated a beneficial effect of pycno…


Natural Factors, Pycnogenol, 25 mg, 60 Vegetarian Capsules

Natural Factors, Pycnogenol, 25 mg, 60 Vegetarian Capsules Review

$15.70

The primary hypothesis was that pine bark extract would lower blood pressure in a population of overweight and obese participants with baseline prehypertension or hypertension. Densiflora bark extract could be a new agent for preventing age-related nuclear cataract. Laboratory evidence suggests that certain specialty dietary supplements have antiinflammatory properties, though evidence in humans remains limited. I have listed the daily dosage recommendations for common applications of pycnogenol, but it is better to consult with your doctor to get more information about the dosage that is right for you taking into account your medical history. Reactive oxygen species (Ros) production, lipid peroxidation, reduction of antioxidant enzymes, crystalline proteolysis, and apoptosis are considered factors that contribute to pathogenesis of age-related nuclear cataract. The strength of this study is that it is the first meta-analysis to assess the potential role of arginine supplements in ed compared with placebo or no treatment. It is a natural source of several antioxidants including proanthocyanidins, which are also found in wine, grapes, apples, cocoa, tea, nuts, and some berries.


Source Naturals, Pycnogenol Supreme, 60 Tablets

Source Naturals, Pycnogenol Supreme, 60 Tablets Review

$24.90

The ingredient is a combination of procyanidins, bioflavonoids and organic acids extracted from the bark of the maritime pine. However, increased platelet reactivity yielding aggregation 2 hours after smoking was prevented by 500 mg aspirin or 100 mg pycnogenol in 22 german heavy smokers. This clustering was in agreement with the atlantic, mediterranean and north african structuration of maritime pine established from terpene data. One critical point with plant extracts is always the bioavailability of their constituents. Investigators and all study staff were blinded to treatment assignment until all study results were collected, at which time the study sponsor revealed which tablet, a or b, contained pine bark extract. This dosage was selected based on the midrange of administration in past studies and the opc content of this pine bark extract compared with other formulations. Studies published to date about the supplement have notable methodological limitations. Pyc also participates in the cellular antioxidant network as indicated by it’s ability to regenerate the ascorbyl radical and to protect endogenous vitamin e and glutathione from oxidative stress.


Source Naturals, Pycnogenol, 100 mg, 60 Tablets

Source Naturals, Pycnogenol, 100 mg, 60 Tablets Review

$42.90

Pine bark extract is generally recognized as safe (Gras) based on data from animal studies and clinical trials; however, few studies evaluate safety as a primary outcome. Pycnogenol (Procyanidins extracted from the bark of pinus maritima aiton) is a potent free radical scavenger. These data begin to provide the basis for the conceptual understanding of the biological activity of pycnogenol and possibly other polyphenolic compounds as therapeutic agents in various human disorders. The extract has been widely studied for the past 40 years and has more than 420 published studies and review articles ensuring safety and efficacy as an ingredient. Debate on antioxidants: Some studies suggest efficacy while others question safety. Without any treatment (Placebo) the retinopathy progressively worsened during the trial and the visual acuity significantly decreased; on the contrary, the pycnogenol-treated patients showed no deterioration of retinal function and a significant recovery of visual acuity was also obtained. It used a rigorous randomized controlled trial method, while most other studies of pine bark extract were open label and lacked clear data collection techniques. In this st…


Allergy Research Group, Pycnogenol 100, 30 Vegetarian Capsules

Allergy Research Group, Pycnogenol 100, 30 Vegetarian Capsules Review

$45.00

In a randomized clinical trial, liu et al 8 found that participants with hypertension taking pine bark extract (100 Mg/d) required lower doses of nifedipine to obtain normal blood pressure but did not test the effect of pine bark extract in the absence of conventional medications. Pine bark extract is generally well tolerated, with occasional minor gastric discomfort, dizziness, nausea, and headache. In a study of 76 people with allergic asthma, pycnogenol (100 Mg/day) added to conventional corticosteroid inhalers for 6 months helped 55% of them reduce inhaler use frequency and dosage. In conclusion, our results demonstrate the anti-inflammatory and antioxidant potential of hiper containing the natural products, pbe, honey, aloe vera, and papain. Pyc also participates in the cellular antioxidant network as indicated by it’s ability to regenerate the ascorbyl radical and to protect endogenous vitamin e and glutathione from oxidative stress. After two weeks of supplementation with pycnogenol, results revealed blood flow increased in response to acetylcholine stimulation by 42 percent. In a study of 61 adhd children, pycnogenol reduced hyperactivity, improved attention, and motoric…


Solgar, Pycnogenol, 30 mg, 30 Vegetable Capsules

Solgar, Pycnogenol, 30 mg, 30 Vegetable Capsules Review

$12.40

Pycnogenol contains active ingredients that can also be found in peanut skin, grape seed, and witch hazel bark. Research has shown that taking pycnogenol daily for 2 months can prevent or reduce the symptoms of retinal disease caused by diseases such as diabetes and atherosclerosis. We chose a population at risk of developing cvd and not taking antihypertensive medications who would be likely to seek dietary supplements as an alternative therapy. Damage caused by free radicals can be minimized by taking antioxidant supplements of key nutrients such as pine bark extract. Approximately 60% of patients treated with pycnogenol(R) experienced a complete disappearance of edema (The most rapidly disappearing symptom) and pain at the end of the treatment, while almost all the patients reported a reduction in leg heaviness which disappeared in approximately 33% of patients. Our objective was to determine the effects of pine bark extract on blood pressure and other cvd risk factors in overweight and obese adults with higher-than-optimal systolic blood pressure. There is growing interest in the biologic activities of plant extracts such as that obtained from the bark of the french maritime…


Solgar, Pycnogenol, 100 mg, 30 Vegetable Capsules

Solgar, Pycnogenol, 100 mg, 30 Vegetable Capsules Review

$34.80

The most important intracellular antioxidant in the human body is glutathione (Gsh). In light of this, the antioxidant mechanisms of pyc are discussed below. These results demonstrate flavonoids participate in the cellular antioxidant network and suggest that pycnogenol may play an important role in the protection of endothelium from oxidative stress induced by reactive nitrogen species. This information relates to an herbal, vitamin, mineral or other dietary supplement. In addition, pycnogenol can help maintain your skin elasticity and hydration and slow the aging process. In the pine bark extract group, there was 1 hospitalization and no emergency department visits. Pine bark extract has been studied in a small clinical trial for pain in the third trimester of pregnancy at a dose of 30 mg/day; however, this should not be regarded as evidence of safety. The study used a randomized, placebo-controlled, double-blind clinical trial design and achieved a sample size larger than most previous studies of pine bark extract.


Life Extension, VenoFlow, 30 Vegetarian Capsules

Life Extension, VenoFlow, 30 Vegetarian Capsules Review

$34.90

And since their primary function is to capture free radicals, these plantioxidants free up vitamin c, so it can perform it’s many other vital functions. In some cases, however, identifying the exact product is difficult, as both grape seed and pine bark opcs, or their combination, have at various times been sold under the same name. Pariza says such debates are common in the field of antioxidants. The original research on sterols and sterolins was based on an extract of the hypoxis plant or african potato. Rhodiola rosea extract, adaptogen for physical and mental stamina. Ayurvedic herb forskohlii extract, forslean forskolin supplements. Suma from brazil, pfaffia paniculata herb supplement. Goji juice, goji berry extract supplement, potent antioxidant protection. A daily low intake of less than one-third of the rda for several of the b vitamins (B1, b2 and b6) and vitamin c, even when other vitamins are supplemented in the diet, may lead to a significant decrease in vo2max and the anaerobic threshold in less than four weeks. Skullcap herb supplement, skullcap extract liquid. Natural carob powder and concentrate supplement. Since the extracts are able to inhibit the breakdown of …


Now Foods, Pycnogenol, 30 mg, 60 Veg Capsules

Now Foods, Pycnogenol, 30 mg, 60 Veg Capsules Review

$12.10

In contrast, serum concentration of vasoconstrictory mediators endothelin-1 and thromboxane are lowered in response to supplementation with pycnogenol. The extract has been widely studied for the past 40 years and has more than 280 published studies and review articles ensuring safety and efficacy as an ingredient. Stress, poor diet, and lack of sleep can all contribute to sub-optimal brain function, and while diet and exercise are fantastic for boosting healthy brain function, so too is pine bark extract. Should i take pycnogenol or regular pine bark extract? The low-dose buildup effect of pycnogenol as an antiinflammatory agent would make it useful in a multinutrient format, but it may not be the most potent antiinflammatory in isolation. Our objective was to determine the effects of pine bark extract on blood pressure and other cvd risk factors in overweight and obese adults with higher-than-optimal systolic blood pressure. Clinical studies using pine bark extracts report no clinically important adverse events at doses of 150 mg daily; however, few studies evaluate safety as a primary outcome. I am taking this in combination with life extension bilberry extract, and it is wor…


Nature’s Way, Pycnogenol, Pine Bark Extract, 50 mg, 30 Tablets

Nature's Way, Pycnogenol, Pine Bark Extract, 50 mg, 30 Tablets Review

$12.90

The extract properties were analyzed using wst-1, lowry, and cell migration assays as well as immunofluorescence staining. In vitro and animal studies using the standardized extract have indicated a multimodal action of pycnogenol, and several human studies have shown improvements in cognitive function after chronic administration. Early empirical usage of pine bark is explained through the observation that the natural pine-bark antioxidants that protect against free oxygen radicals also possess anti-inflammatory activity. We previously reported that pycnogenol prevents vascular endothelial cells from injury induced by an organic oxidant t-butyl hydroperoxide. It is the largest study to date of pine bark extract and cvd risk factors. The adverse events and adverse effects questionnaire asked about symptoms commonly reported in past studies of pine bark extract, hospital and emergency department visits, new diagnoses, and changes in existing diagnoses. Consistent with our recruitment of a population with blood pressures above the normal (120/80 Mm hg) range, the mean (Sd) blood pressures at baseline were 132,6 (10,9)/78,6 (7,9) Mm hg for the pine bark extract group and 133,2 (10,…


Now Foods, Pine Bark Extract, 240 mg, 90 Veg Capsules

Now Foods, Pine Bark Extract, 240 mg, 90 Veg Capsules Review

$10.50

Also, 50 mg of the same extract has been used twice daily for 6 months. Thus, enos is closely involved in the renoprotective effects of ge, strongly suggesting that ge supplements are useful as a prophylactic treatment for the development of ischemic aki. Reactive oxygen species (Ros) production, lipid peroxidation, reduction of antioxidant enzymes, crystalline proteolysis, and apoptosis are considered factors that contribute to pathogenesis of age-related nuclear cataract. Pyg has been suggested to protect tissues from oxidative stress-related damage in diabetes due to it’s strong antioxidant activity. This is the first report about positive cellular effects of a dietary supplement on key catabolic and inflammatory markers in patients with severe oa. Radiata bark extract effectively inhibits anaphylaxis-like reactions. As a member of the flavonoid family, opcs have established free radical scavenging and antioxidant activity. Probiotic complex, zinc, and coenzyme q10 (Coq10) are recognized dietary supplements with an anti-inflammatory role.


Life Extension, Pycnogenol, French Maritime Pine Bark Extract, 100 mg, 60 Vegetarian Capsules

Life Extension, Pycnogenol, French Maritime Pine Bark Extract, 100 mg, 60 Vegetarian Capsules Review

$45.60

In this study, we determined the effects of pycnogenol on (A) oxidative burst of macrophages, (B) oxidation of plasma low density lipoprotein (Ldl), and (C) hydroxyl radical-induced breakage of plasmid dna. Although the study design was weak, other studies demonstrating that pycnogenol has a relaxing effect on intestinal smooth muscle tissue lends some increased confidence that it may also be effective as a treatment for ibs. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. We identified nine trials involving 549 participants who received pycnogenol supplementation ranging from 150 mg/d to 200 mg/d. No side effects due to supplementation were observed; tolerability was optimal. Received research grants from horphag research, the producer of pycnogenol, within the past five years. That said, there are some instances where this extract may possibly be effective.


Now Foods, Pycnogenol, 60 mg, 50 Veg Capsules

Now Foods, Pycnogenol, 60 mg, 50 Veg Capsules Review

$17.80

The mixed results suggest that pycnogenol blood-pressure lowering effects may be dependent on the underlying cause of hypertension. In vitro studies suggest pine bark extract exhibits a number of beneficial effects, including inhibition of lipid accumulation in adipocytes, stimulation of lipolysis, and increased glucose uptake. Pycnogenol supplementation reduced skin redness from uv rays in a trial of 21 people over 8 weeks. In addition to the antioxidant activity, pycnogenol enhances production of vasodilatory endothelial nitric oxide and prostacyclin. Antidiabetic effect of pycnogenol french maritime pine bark extract in patients with diabetes type ii. Early empirical usage of pine bark is explained through the observation that the natural pine-bark antioxidants that protect against free oxygen radicals also possess anti-inflammatory activity. This may account for variations in physiologic effects among different pine bark extract preparations and among antioxidants in general. To evaluate the efficacy and safety of orally administered grape seed proanthocyanidin extract (Gspe) in patients with non-proliferative diabetic retinopathy (Npdr). Consistent with our recruitment of a…


Source Naturals, Pine Bark Extract, 60 Tablets

Source Naturals, Pine Bark Extract, 60 Tablets Review

$5.80

A trial of children with adhd found that pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing dna damage. Early research suggests that taking a standardized extract of maritime pine bark by mouth reduces symptoms of sle in some patients. These data suggest that interactions between the major constituents of this supplement combination are unlikely and therefore could be investigated to manage patients with osteoarthritis without significant concerns for possible pharmacokinetic interactions. We therefore propose that proanthocyanidins are superior antioxidants as compared to flavon(Ol)s proper, whose quinones are more likely to redox-cycle and act as prooxidants. The most important intracellular antioxidant in the human body is glutathione (Gsh). There were no subgroups for whom intake of pine bark extract affected cardiovascular disease risk factors. This information relates to an herbal, vitamin, mineral or other dietary supplement. In this study, the needle extract of 5lp was fractionated and analyzed by lc/ms/ms to search for possible antihypertensive candidates. Pycnogenol is a patented extract of the french maritime pine bark (…


Natural Factors, Pycnogenol, 25 mg, 60 Vegetarian Capsules

Natural Factors, Pycnogenol, 25 mg, 60 Vegetarian Capsules Review

$15.70

These data suggest that interactions between the major constituents of this supplement combination are unlikely and therefore could be investigated to manage patients with osteoarthritis without significant concerns for possible pharmacokinetic interactions. This is how i know that this product works as well as branded pycnogenol because i truly felt the difference without it. In rodent studies, pine bark extract showed antioxidant effects and improved insulin resistance and hyperglycemia. All five studies reported subjective improvements in cvi-related symptoms in the pycnogenol treatment groups. The aim of this study was to explore in a pilot trial whether supplementation with french maritime pine bark extract pycnogenol could alleviate side effects and improve patient’s quality of life. A study of 58 patients with hypertension showed that 100 mg of pycnogenol daily had a positive effect on their blood pressure. 9 By administering a combined daily dose of pine bark extract, 480 mg, and vitamin c, 240 mg, to 24 healthy subjects in an open-label preevaluation and postevaluation, shand et al 12 found a significant decrease of 7 mm hg in the mean systolic blood pressure at 6 weeks…


Source Naturals, Pycnogenol Supreme, 30 Tablets

Source Naturals, Pycnogenol Supreme, 30 Tablets Review

$12.90

I’ve been using pycnogenol for a couple of years now for tinnitus. In a study of 61 adhd children, pycnogenol reduced hyperactivity, improved attention, and motorics after 1 month. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. These data suggest that interactions between the major constituents of this supplement combination are unlikely and therefore could be investigated to manage patients with osteoarthritis without significant concerns for possible pharmacokinetic interactions. There is absolutely no application of pesticides during the growing of the pine trees or toxic solvents during the manufacture of the french maritime pine bark extract, therefore it does not contain any pesticide or solvents. For 12 weeks, participants took either the pine bark extract or a placebo. Pine bark was significantly more effective than the placebo in all these aspects. Pine bark has been used as a food source in emergencies.


California Gold Nutrition, French Maritime Pine Bark Extract, Oligopin, Antioxidant Polyphenol, 100 mg, 60 Veggie Caps

California Gold Nutrition, French Maritime Pine Bark Extract, Oligopin, Antioxidant Polyphenol, 100 mg, 60 Veggie Caps Review

$18.80

In this study, we determined the effects of pycnogenol on (A) oxidative burst of macrophages, (B) oxidation of plasma low density lipoprotein (Ldl), and (C) hydroxyl radical-induced breakage of plasmid dna. The proprietary extract comes from the bark of the french maritime pine tree pinas pinaster, which grows on the coast of southwest france. A trial of 84 people found that both pycnogenol oral supplements and creams (0,5%) May prevent hemorrhoids from bleeding during acute attacks after 7 days. Since grape extract (Ge) contains oligomeric proanthocyanidins and numerous polyphenols, dietary ge supplements may exert protective effects against various diseases. This is the best antioxidant i have ever used! You may also be interested in taking an eye health supplement. Radiata bark extract effectively inhibits anaphylaxis-like reactions. 2, 3, 5 The pharmacokinetics of maritime pine bark extract constituents have been studied in human volunteers. Pine bark extract has been studied for multiple conditions including diabetic retinopathy and ulceration, tinnitus, hemorrhoids, hyperpigmentation in melasma, menopausal symptoms, motion sickness, traveler’s thrombosis, control of inflam…


Nutricology, Pycnogenol 100, 30 Vegetarian Capsules

Nutricology, Pycnogenol 100, 30 Vegetarian Capsules Review

$33.70

In addition to main stream medical treatments, there is increasing popularity in using natural compounds for their intrinsic anti-inflammatory and antioxidant properties. Without any treatment (Placebo) the retinopathy progressively worsened during the trial and the visual acuity significantly decreased; on the contrary, the pycnogenol-treated patients showed no deterioration of retinal function and a significant recovery of visual acuity was also obtained. In conclusion, our results demonstrate the anti-inflammatory and antioxidant potential of hiper containing the natural products, pbe, honey, aloe vera, and papain. The adverse events and adverse effects questionnaire asked about symptoms commonly reported in past studies of pine bark extract, hospital and emergency department visits, new diagnoses, and changes in existing diagnoses. Currently pycnogenol is available in a number of forms, as a dietary supplement, a powder or cream that is often used in cosmetics, a multi-vitamin, and other health products such as health drinks. Doses of pine bark extract have been studied in clinical trials, most commonly at 150 mg per day in 3 divided doses. You are using anticoagulant and/or…


Country Life, Grape Complete, Includes Pine Bark, 90 Veggie Caps

Country Life, Grape Complete, Includes Pine Bark, 90 Veggie Caps Review

$20.20

French maritime pine bark pinus pinaster ait. It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa. In vitro evaluation of the anti-digestion and antioxidant effects of grape seed procyanidins according to their degrees of polymerization. Masquelier termed the active ingredients of the pine bark pycnogenols, which today are referred to in the scientific community as oligomeric proanthocyanidins, or opcs. Trials of pine bark extract have shown decreases in ldl-c level, 6, 23 while equal numbers of trials, including ours, reported no significant benefits of pine bark extract on ldl-c level. Results herein revealed the considerable potential of grape seeds, a by-product of the vinification process, as a valuable inexpensive source of high added value of nutritionally beneficial compounds – polyphenol and tocol antioxidants and macro- and microelements for use as feed additives in animal nutrition. There were five cases of dvts or superficial thrombosis in the placebo group, as compared to none in the opc group, a difference that was statistically significant. Grape seed extract …